دورية أكاديمية
Repeat breast-conserving therapy for ipsilateral breast cancer recurrence: A systematic review.
| العنوان: | Repeat breast-conserving therapy for ipsilateral breast cancer recurrence: A systematic review. |
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| المؤلفون: | Walstra CJEF; Department of Surgery, Catharina Hospital Eindhoven, the Netherlands. Electronic address: coco-walstra@live.nl., Schipper RJ; Department of Surgery, Catharina Hospital Eindhoven, the Netherlands., Poodt IGM; Department of Surgery, Catharina Hospital Eindhoven, the Netherlands., van Riet YE; Department of Surgery, Catharina Hospital Eindhoven, the Netherlands., Voogd AC; Department of Epidemiology, Maastricht University Medical Center, Maastricht, the Netherlands; Department of Research, Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, the Netherlands; GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, the Netherlands., van der Sangen MJC; Department of Radiotherapy, Catharina Hospital Eindhoven, the Netherlands., Nieuwenhuijzen GAP; Department of Surgery, Catharina Hospital Eindhoven, the Netherlands. |
| المصدر: | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology [Eur J Surg Oncol] 2019 Aug; Vol. 45 (8), pp. 1317-1327. Date of Electronic Publication: 2019 Feb 10. |
| نوع المنشور: | Journal Article; Systematic Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 8504356 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2157 (Electronic) Linking ISSN: 07487983 NLM ISO Abbreviation: Eur J Surg Oncol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Original Publication: London ; New York : Academic Press, [1985- |
| مواضيع طبية MeSH: | Breast Neoplasms/*surgery , Mastectomy, Segmental/*methods , Neoplasm Recurrence, Local/*mortality , Neoplasm Recurrence, Local/*surgery , Reoperation/*methods , Salvage Therapy/*methods, Adult ; Aged ; Breast Neoplasms/mortality ; Breast Neoplasms/pathology ; Disease-Free Survival ; Female ; Humans ; Mastectomy, Segmental/adverse effects ; Middle Aged ; Neoplasm Invasiveness/pathology ; Neoplasm Recurrence, Local/pathology ; Neoplasm Recurrence, Local/radiotherapy ; Neoplasm Staging ; Prognosis ; Radiotherapy, Adjuvant ; Reoperation/mortality ; Risk Assessment ; Salvage Therapy/mortality ; Survival Analysis ; Treatment Outcome |
| مستخلص: | The standard of care for patients with an ipsilateral breast tumour recurrence (IBTR) after breast-conserving therapy (BCT) is a salvage mastectomy. However, there is growing interest in the feasibility of repeat BCT for these patients. This systematic review contains the latest insights on BCT options for patients with an IBTR after initial BCT. A PubMed literature search was performed for articles on BCT options for IBTR after primary lumpectomy followed by radiotherapy. Weighted estimates were calculated for 5- and 10-year local control, distant metastasis-free and overall survival rates. Secondary outcomes were toxicity, cosmesis and quality of life. In total, 34 studies were eligible for analysis, of which 5 reported on repeat breast-conserving surgery (BCS) alone, 10 with mixed populations (BCS ± RT and/or mastectomy), 18 on repeat BCS followed by re-irradiation (whole-breast or partial) and one on quality of life. The weighted estimates for 5-year overall survival for repeat BCS and repeat BCS followed by reirradiation were 77% and 87%, respectively. Five-year local control was 76% for repeat BCS alone and 89% for repeat BCS followed by re-irradiation. Grade III-IV toxicity rates after re-irradiation varied from 0 to 21%, whereas the cosmesis was excellent-good in 29-100% of patients and unacceptable in 0-18%. Repeat BCS followed by re-irradiation, with either whole breast or partial breast re-irradiation, seems a feasible alternative to mastectomy in case of IBTR, in selected patients. Toxicity rates are low and the cosmetic outcome is good, but the size and follow-up of the published patient series is limited. (Copyright © 2019 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Breast-conserving therapy; IBTR; Recurrent breast cancer; Repeat breast irradiation; Repeat breast-conserving therapy |
| تواريخ الأحداث: | Date Created: 20190224 Date Completed: 20200611 Latest Revision: 20200611 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.ejso.2019.02.008 |
| PMID: | 30795956 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1532-2157 |
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| DOI: | 10.1016/j.ejso.2019.02.008 |