دورية أكاديمية
Synchronous gallbladder adenocarcinoma and gastric gastrointestinal stromal tumor: Case report and literature review.
| العنوان: | Synchronous gallbladder adenocarcinoma and gastric gastrointestinal stromal tumor: Case report and literature review. |
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| المؤلفون: | Peitl Gregório PH; Division of General Surgery, Hospital Israelita Albert Einstein, São Paulo, Brazil. Electronic address: phpgregorio@gmail.com., Takemura LS; Division of General Surgery, Hospital Israelita Albert Einstein, São Paulo, Brazil. Electronic address: lucas.takemura@einstein.br., Vilela Galvão AL; Division of General Surgery, Hospital Israelita Albert Einstein, São Paulo, Brazil. Electronic address: andre.vilela@einstein.br., Gagliotti GC; Division of General Surgery, Hospital Israelita Albert Einstein, São Paulo, Brazil. Electronic address: giuliano.gagliotti@einstein.br., Leão Edelmuth RC; Division of General Surgery, Hospital Israelita Albert Einstein, São Paulo, Brazil. Electronic address: rodrigo.edelmuth@me.com., Segatelli V; Division of Pathology, Hospital Israelita Albert Einstein, São Paulo, Brazil. Electronic address: vanderlei.segatelli@einstein.br. |
| المصدر: | International journal of surgery case reports [Int J Surg Case Rep] 2019; Vol. 56, pp. 25-28. Date of Electronic Publication: 2019 Feb 13. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101529872 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2210-2612 (Print) Linking ISSN: 22102612 NLM ISO Abbreviation: Int J Surg Case Rep Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Amsterdam] : Elsevier B.V. |
| مستخلص: | Introduction: Synchronous occurrence of different types of neoplasms is not very frequent, representing around 6% of all cases of cancer. Usually there is a lack of information on how to treat these patients, especially when both types of cancers are also uncommon. No cases of synchronous gallbladder adenocarcinoma and gastric gastrointestinal stromal tumor have been published before. Presentation of Case: We present the case, management and follow-up, of a 66-year-old female with incidental diagnosis of a pT2NxMx gallbladder adenocarcinoma after elective cholecystectomy that latter, during staging, was also diagnosed with GIST. Total gastrectomy, wedge resection of the liver and lymphadenectomy were performed due to the new findings. Adjuvant chemotherapy for 36 months was indicated. After 16 months of the treatment she has no signs of recurrence. Discussion: Gastrointestinal stromal tumors (GISTs) had a turnaround in the end of the 20th century after the introduction tyrosine-kinase inhibitor to the adjuvant treatment and now the trend is to extend it up to 36 months in selected patients. Gallbladder adenocarcinoma is an uncommon cancer but the incidental diagnosis is increasing with the popularity of laparoscopic cholecystectomy and, thus, specific management should be offered for these patients, what frequently includes a complementary surgery. Although, GISTs may be associated with another synchronous tumor in 20% of the cases, the simultaneous occurrence with gallbladder cancer is incredibly rare. Conclusion: Simultaneous occurrence of gastric GIST and gallbladder adenocarcinoma has not been reported before and, thus, any information about it may help in the management of those patients. (Copyright © 2019. Published by Elsevier Ltd.) |
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| فهرسة مساهمة: | Keywords: Case report; Gallbladder adenocarcinoma; Gastrointestinal stromal tumor; Synchronous neoplasms |
| تواريخ الأحداث: | Date Created: 20190301 Latest Revision: 20200928 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC6393670 |
| DOI: | 10.1016/j.ijscr.2019.02.001 |
| PMID: | 30818158 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 2210-2612 |
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| DOI: | 10.1016/j.ijscr.2019.02.001 |