دورية أكاديمية
(Re)organisation of the somatosensory system after early brain lesion: A lateralization index fMRI study.
| العنوان: | (Re)organisation of the somatosensory system after early brain lesion: A lateralization index fMRI study. |
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| المؤلفون: | Lemée JM; Département de neurochirurgie, CHU Angers, 49933 Angers, France. Electronic address: lemee.jmichel@wanadoo.fr., Chinier E; Département de médecine physique et de réadaptions, CHU Angers-Capucins, 49933 Angers, France., Ali P; Département de médecine physique et de réadaptions, CHU Angers-Capucins, 49933 Angers, France; EA7315, laboratoire Angevin de recherche en ingénierie des systèmes (LARIS), université d'Angers, 49000 Angers, France., Labriffe M; Département de radiologie, CHU Angers, 49933 Angers, France., Ter Minassian A; EA7315, laboratoire Angevin de recherche en ingénierie des systèmes (LARIS), université d'Angers, 49000 Angers, France; Pôle d'anesthésie réanimation, CHU Angers, 49933 Angers, France., Dinomais M; Département de médecine physique et de réadaptions, CHU Angers-Capucins, 49933 Angers, France; EA7315, laboratoire Angevin de recherche en ingénierie des systèmes (LARIS), université d'Angers, 49000 Angers, France. |
| المصدر: | Annals of physical and rehabilitation medicine [Ann Phys Rehabil Med] 2020 Oct; Vol. 63 (5), pp. 416-421. Date of Electronic Publication: 2019 Feb 27. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Masson Country of Publication: Netherlands NLM ID: 101502773 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1877-0665 (Electronic) Linking ISSN: 18770657 NLM ISO Abbreviation: Ann Phys Rehabil Med Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam : Elsevier Masson |
| مواضيع طبية MeSH: | Cerebral Palsy* , Magnetic Resonance Imaging*, Cerebral Cortex ; Humans ; Somatosensory Cortex/diagnostic imaging |
| مستخلص: | Objective: To evaluate the relationship between neural (re)organization of the somatosensory cortex and impairment of sensory function (2-point discrimination [2PD]) in individuals with unilateral cerebral palsy. Methods: We included 21 individuals with unilateral cerebral palsy. 2PD thresholds were evaluated on thumb pads, and activation of the somatosensory cortex was recorded by functional MRI (fMRI) during passive movements of the affected hand. A lateralization index (LI) was calculated for the primary sensory (S1) and secondary sensory (S2) cortices and the correlation between the LI and 2PD thresholds was analysed. Results: We found a significant negative correlation between the 2PD thresholds and the S2 LI (r=-0.5, one-tailed P-value=0.01) and a trend towards a negative correlation with the S1 LI (r=-0.4, one-tailed P-value=0.05). Conclusion: High levels of activation in the contralesional hemisphere were associated with high levels of sensory impairment in individuals with unilateral cerebral palsy. The interhemispheric (re)organization of the somatosensory system may not effectively compensate for somatosensory impairment. (Copyright © 2019 Elsevier Masson SAS. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Brain lesion; Cerebral palsy; Functional MRI; Lateralization index; Plasticity; Sensory function |
| تواريخ الأحداث: | Date Created: 20190303 Date Completed: 20211125 Latest Revision: 20211125 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.rehab.2019.02.001 |
| PMID: | 30825646 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1877-0665 |
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| DOI: | 10.1016/j.rehab.2019.02.001 |