دورية أكاديمية
[Chemiluminescence of human neutrophils as affected by opportunistic microbes].
| العنوان: | [Chemiluminescence of human neutrophils as affected by opportunistic microbes]. |
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| عنوان ترانسليتريتد: | Khemiliuminestsentsiia neĭtrofilov cheloveka pod deĭstviem uslovno-patogennykh mikrobov. |
| المؤلفون: | Belotskiĭ SM, Filiukova OB, Pashutin SB, Dikovskaia ES, Bazanova EB |
| المصدر: | Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 1986 Mar (3), pp. 89-92. |
| نوع المنشور: | Comparative Study; Journal Article |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: FBUN T︠S︡NII Ėpidemiologii Rospotrebnadzora Country of Publication: Russia (Federation) NLM ID: 0415217 Publication Model: Print Cited Medium: Print ISSN: 0372-9311 (Print) Linking ISSN: 03729311 NLM ISO Abbreviation: Zh Mikrobiol Epidemiol Immunobiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2018, no. 4 (ii︠u︡lʹ-avgust)- >: Moskva : FBUN T︠S︡NII Ėpidemiologii Rospotrebnadzora Original Publication: Moskva : Izd-vo "Medit︠s︡ina" |
| مواضيع طبية MeSH: | Luminescent Measurements*, Escherichia coli/*immunology , Neutrophils/*immunology , Pseudomonas aeruginosa/*immunology , Staphylococcus aureus/*immunology, Antigens, Bacterial/immunology ; Erythrocytes/immunology ; Humans ; Hydrogen Peroxide/metabolism ; Opsonin Proteins/immunology ; Time Factors |
| مستخلص: | Chemoluminescence of neutrophils obtained from 24 healthy donors in response to Staphylococcus aureus Cowan, Pseudomonas aeruginosa and Escherichia coli preopsonized with 5% fresh autologous serum or with pooled normal sera was studied. Chemoluminescent response to S. aureus was most pronounced in comparison with that to the other microbes. Neutrophils from most of the donors showed chemiluminescent response of medium intensity, their stimulation index (SI) being 10-12; neutrophils from some donors showed low response (their SI not exceeding 10), and some donors provided highly responsive neutrophils (their SI exceeding 20). Neutrophils from the latter group of donors retained their high SI over the longest period of time (60 minutes and more). Experiments made under the conditions of preopsonization with pooled normal sera indicated that differences in the response of neutrophils were linked with the individual features of these cells. Low response to P. aeruginosa and E. coli was, possibly, due to the antiphagocytic activity of these microorganisms. Differences in the response of neutrophils to antigens of opportunistic microbes, as well as in the dependence of this response from serum factors, may finally determine the result of the interaction between host defence factors and microorganisms at the infection atrium. |
| المشرفين على المادة: | 0 (Antigens, Bacterial) 0 (Opsonin Proteins) BBX060AN9V (Hydrogen Peroxide) |
| تواريخ الأحداث: | Date Created: 19860301 Date Completed: 19860618 Latest Revision: 20201209 |
| رمز التحديث: | 20221213 |
| PMID: | 3085413 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0372-9311 |
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