دورية أكاديمية
أعرض في EDS

Combined effect of conventional antimicrobials with essential oils and their main components against resistant Streptococcus suis strains.

التفاصيل البيبلوغرافية
العنوان: Combined effect of conventional antimicrobials with essential oils and their main components against resistant Streptococcus suis strains.
المؤلفون: de Aguiar FC; Departamento de Sanidad Animal, Universidad de Córdoba, International Excellence Agrifood Campus 'CeiA3', Córdoba, Spain., Solarte AL; Departamento de Sanidad Animal, Universidad de Córdoba, International Excellence Agrifood Campus 'CeiA3', Córdoba, Spain.; Medicine Faculty, University Cooperative of Colombia, Pasto, Colombia., Tarradas C; Departamento de Sanidad Animal, Universidad de Córdoba, International Excellence Agrifood Campus 'CeiA3', Córdoba, Spain., Gómez-Gascón L; Departamento de Sanidad Animal, Universidad de Córdoba, International Excellence Agrifood Campus 'CeiA3', Córdoba, Spain., Astorga R; Departamento de Sanidad Animal, Universidad de Córdoba, International Excellence Agrifood Campus 'CeiA3', Córdoba, Spain., Maldonado A; Departamento de Sanidad Animal, Universidad de Córdoba, International Excellence Agrifood Campus 'CeiA3', Córdoba, Spain., Huerta B; Departamento de Sanidad Animal, Universidad de Córdoba, International Excellence Agrifood Campus 'CeiA3', Córdoba, Spain.
المصدر: Letters in applied microbiology [Lett Appl Microbiol] 2019 Jun; Vol. 68 (6), pp. 562-572. Date of Electronic Publication: 2019 Apr 25.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 8510094 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1472-765X (Electronic) Linking ISSN: 02668254 NLM ISO Abbreviation: Lett Appl Microbiol Subsets: MEDLINE
أسماء مطبوعة: Publication: 2023- : Oxford : Oxford University Press
Original Publication: Oxford, UK : Published for the Society for Applied Bacteriology by Blackwell Scientific Publications, [c1985-
مواضيع طبية MeSH: Acrolein/*analogs & derivatives , Anti-Bacterial Agents/*pharmacology , Monoterpenes/*pharmacology , Oils, Volatile/*pharmacology , Streptococcus suis/*drug effects , Swine Diseases/*drug therapy , Thymol/*pharmacology, Acrolein/pharmacology ; Animals ; Cinnamomum zeylanicum/chemistry ; Cymenes ; Drug Resistance, Multiple, Bacterial ; Microbial Sensitivity Tests ; Origanum/chemistry ; Streptococcus suis/growth & development ; Swine ; Swine Diseases/microbiology ; Thymus Plant/chemistry
مستخلص: Streptococcus suis is a major swine pathogen. Different strategies to reduce the antimicrobial resistance to conventional antimicrobials (AMBs) have been proposed, including the combined use with essential oils (EOs). The objective of this work was to evaluate the effectiveness of the combination of cinnamon, oregano, common thyme and red thyme EOs and their main components (cinnamaldehyde, carvacrol and thymol) with conventional AMBs (oxytetracycline, trimethoprim-sulfamethoxazole, gentamicin and penicillin) against field resistant S. suis strains. The checkerboard method was used to assess the interaction, by the fractional inhibitory concentration index (FIC index ) determination. All the AMBs showed synergistic (FIC index  ≤ 0·5) or additive (0·5 < FIC index  ≤ 1) effect with at least one of the four essential oils. In general, the combination of the AMBs with the EOs showed better results than combination the AMBs with the main components, although no antagonist effects were detected in any case. The results obtained would support the combined use of AMBs agents with EOs for the treatment of S. suis. SIGNIFICANCE AND IMPACT OF THE STUDY: Streptococcus suis is an important pig pathogen and a zoonosis. Control is based on antimicrobials; however, there is pressure to reduce the use of antimicrobials and new products or combination therapies are of considerable interest. We have evaluated the combined interaction of four essential oils or their main components with conventional antimicrobials against resistant S. suis strains. A positive interaction between gentamicin and oxytetracycline with cinnamon, oregano or thyme was observed, suggesting that a combination of conventional antimicrobials with EOs is a promising alternative for the control of S. suis infections.
(© 2019 The Society for Applied Microbiology.)
فهرسة مساهمة: Keywords: Streptococcus suis; antimicrobial interactions; conventional antimicrobials; essential oils; main components
المشرفين على المادة: 0 (Anti-Bacterial Agents)
0 (Cymenes)
0 (Monoterpenes)
0 (Oils, Volatile)
3J50XA376E (Thymol)
7864XYD3JJ (Acrolein)
9B1J4V995Q (carvacrol)
SR60A3XG0F (cinnamaldehyde)
تواريخ الأحداث: Date Created: 20190313 Date Completed: 20190701 Latest Revision: 20210702
رمز التحديث: 20221213
DOI: 10.1111/lam.13151
PMID: 30861569
قاعدة البيانات: MEDLINE
الوصف
تدمد:1472-765X
DOI:10.1111/lam.13151