دورية أكاديمية
More Than 25 Years Together: Basis for a Long-Lifespan Kidney Transplant.
العنوان: | More Than 25 Years Together: Basis for a Long-Lifespan Kidney Transplant. |
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المؤلفون: | Díaz LS; Nephrology Department, HUCA, Oviedo, Spain. Electronic address: lucia.sobrino@gmail.com., Fraile MG; Nephrology Department, HUCA, Oviedo, Spain; Red Investigación Renal (REDINREN), Madrid, Spain., López ACA; Nephrology Department, HUCA, Oviedo, Spain., Fernández MLS; Nephrology Department, HUCA, Oviedo, Spain; Red Investigación Renal (REDINREN), Madrid, Spain., Cano NR; Nephrology Department, HUCA, Oviedo, Spain., Díaz-Corte C; Nephrology Department, HUCA, Oviedo, Spain; Red Investigación Renal (REDINREN), Madrid, Spain. |
المصدر: | Transplantation proceedings [Transplant Proc] 2019 Mar; Vol. 51 (2), pp. 334-336. Date of Electronic Publication: 2018 Oct 28. |
نوع المنشور: | Journal Article; Observational Study |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 0243532 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2623 (Electronic) Linking ISSN: 00411345 NLM ISO Abbreviation: Transplant Proc Subsets: MEDLINE |
أسماء مطبوعة: | Publication: New York, N.Y. : Elsevier Science Inc. Original Publication: New York Stratton. |
مواضيع طبية MeSH: | Histocompatibility* , Tissue Donors*, Graft Survival/*physiology , Kidney Transplantation/*methods, Adolescent ; Adult ; Child ; Female ; Graft Rejection/physiopathology ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Young Adult |
مستخلص: | Patients with graft survival for 20 years or more are not uncommon; they are called ultralong kidney recipients. It is interesting to know if there are patterns in donors and recipients that could be reproduced. A retrospective cohort with 22 adult patients with a kidney renal transplant performed more than 25 years ago is analyzed. The mean of age of the donors was 24 years (median, 21 years); 82% were men and the cause of death was mainly acute traumatic brain injury. Recipients had a mean age of 34 years (median, 36 years) at the time of transplant; the most common underlying renal disease was glomerular, without evidence of recurrence. A total of 16 patients had compatibility in HLA II (1 in 11 cases; 2 in 5 cases). Only 6 patients have had any episode of acute rejection; 3 of them have developed antibodies class I, but no donor-specific antibodies. In this retrospective cohort, increases in donor age are associated with poor renal function. The mean creatinine is 1.43 mg/dL (range, 0.97-2.14 mg/dL) and mean proteinuria is 653.43 mg/g (range, 55-3722 mg/g). The characteristics common in ultralong kidney recipients are young male donors, a shortage of episodes of rejection, and good HLA compatibility, especially in class II antigens. (Copyright © 2018 Elsevier Inc. All rights reserved.) |
تواريخ الأحداث: | Date Created: 20190319 Date Completed: 20190514 Latest Revision: 20190514 |
رمز التحديث: | 20231215 |
DOI: | 10.1016/j.transproceed.2018.10.007 |
PMID: | 30879535 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1873-2623 |
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DOI: | 10.1016/j.transproceed.2018.10.007 |