دورية أكاديمية
The role of marine omega-3 in human neurodevelopment, including Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder - a review.
| العنوان: | The role of marine omega-3 in human neurodevelopment, including Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder - a review. |
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| المؤلفون: | Martins BP; Department of Clinical Neurosciences and Mental Health, Medical Psychology, Faculty of Medicine, University of Porto, Porto, Portugal., Bandarra NM; Department of Sea and Marine Resources, Portuguese Institute for the Sea and Atmosphere (IPMA, IP), Lisbon, Portugal., Figueiredo-Braga M; Department of Clinical Neurosciences and Mental Health, Medical Psychology, Faculty of Medicine, University of Porto, Porto, Portugal.; Research Group: Metabolism, Nutrition & Endocrinology, i3S Instituto de Investigação e Inovação em Saúde, Porto, Portugal. |
| المصدر: | Critical reviews in food science and nutrition [Crit Rev Food Sci Nutr] 2020; Vol. 60 (9), pp. 1431-1446. Date of Electronic Publication: 2019 Mar 18. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Group Country of Publication: United States NLM ID: 8914818 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-7852 (Electronic) Linking ISSN: 10408398 NLM ISO Abbreviation: Crit Rev Food Sci Nutr Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Philadelphia, PA : Taylor & Francis Group Original Publication: Boca Raton, Fla. : CRC Press, c1980- |
| مواضيع طبية MeSH: | Attention Deficit Disorder with Hyperactivity/*metabolism , Autism Spectrum Disorder/*metabolism , Fatty Acids, Omega-3/*metabolism, Docosahexaenoic Acids/metabolism ; Fatty Acids, Omega-6/metabolism ; Female ; Humans ; Pregnancy |
| مستخلص: | Autism Spectrum Disorders (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) are two increasingly prevalent neurodevelopmental disorders. This rise may be associated with a higher dietary intake of n-6 polyunsaturated fatty acids (PUFAs) and lower of n-3 PUFAs. Docosahexaenoic acid (DHA), a key nutritional n-3 PUFA, is crucial for an optimal offspring's neurodevelopment through the last trimester of pregnancy. Recently, lower DHA levels have been reported in children with ASD and ADHD. The present review summarizes the main research achievements concerning the effect of DHA in children neurodevelopment, in order to elicit its role in the prevention and mitigation of ASD and ADHD. As main finding, a low DHA supply seems to negatively affect childhood neurodevelopment in specific conditions and increase the risk and the severity of ASD or ADHD. Higher DHA status at birth was associated with better childhood neurodevelopmental, but controversial results found in prenatal supplementation raised the hypothesis that the benefits of DHA may be influenced by other factors as socio-economic background and life-style. In conclusion, an optimal DHA provision through maternal diet or breastfeed may promote some neuronal protection in specific offspring's populations, suggesting that DHA may act as a modifiable risk factor for ASD and ADHD. |
| فهرسة مساهمة: | Keywords: Neurodevelopment; docosahexaenoic acid; lactation; maternal seafood intake; n-3 Polyunsaturated Fatty Acids; pregnancy |
| المشرفين على المادة: | 0 (Fatty Acids, Omega-3) 0 (Fatty Acids, Omega-6) 25167-62-8 (Docosahexaenoic Acids) |
| تواريخ الأحداث: | Date Created: 20190319 Date Completed: 20200422 Latest Revision: 20200422 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1080/10408398.2019.1573800 |
| PMID: | 30880398 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1549-7852 |
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| DOI: | 10.1080/10408398.2019.1573800 |