دورية أكاديمية
Clinical Manifestations and Molecular Diagnosis of Scrub Typhus and Murine Typhus, Vietnam, 2015-2017.
| العنوان: | Clinical Manifestations and Molecular Diagnosis of Scrub Typhus and Murine Typhus, Vietnam, 2015-2017. |
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| المؤلفون: | Trung NV, Hoi LT, Dien VM, Huong DT, Hoa TM, Lien VN, Van Luan P, Lewycka SO, Choisy M, Bryant JE, Nadjm B, Rogier van Doorn H, Richards AL, Van Kinh N |
| المصدر: | Emerging infectious diseases [Emerg Infect Dis] 2019 Apr; Vol. 25 (4). |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Atlanta, GA : National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), [1995- |
| مواضيع طبية MeSH: | Scrub Typhus/*diagnosis , Scrub Typhus/*physiopathology , Typhus, Endemic Flea-Borne/*diagnosis , Typhus, Endemic Flea-Borne/*physiopathology, Adult ; Early Diagnosis ; Female ; Humans ; Male ; Middle Aged ; Pathology, Molecular ; Prospective Studies ; Scrub Typhus/epidemiology ; Serotyping ; Typhus, Endemic Flea-Borne/epidemiology ; Vietnam |
| مستخلص: | Rickettsioses are endemic to Vietnam; however, only a limited number of clinical studies have been performed on these vectorborne bacteria. We conducted a prospective hospital-based study at 2 national referral hospitals in Hanoi to describe the clinical characteristics of scrub typhus and murine typhus in northern Vietnam and to assess the diagnostic applicability of quantitative real-time PCR assays to diagnose rickettsial diseases. We enrolled 302 patients with acute undifferentiated fever and clinically suspected rickettsiosis during March 2015-March 2017. We used a standardized case report form to collect clinical information and laboratory results at the time of admission and during treatment. We confirmed scrub typhus in 103 (34.1%) patients and murine typhus in 12 (3.3%) patients. These results highlight the need for increased emphasis on training for healthcare providers for earlier recognition, prevention, and treatment of rickettsial diseases in Vietnam. |
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| معلومات مُعتمدة: | United Kingdom Wellcome Trust |
| فهرسة مساهمة: | Keywords: Scrub typhus; Vietnam; bacteria; clinical manifestations; molecular diagnosis; murine typhus; rickettsial diseases |
| تواريخ الأحداث: | Date Created: 20190319 Date Completed: 20191224 Latest Revision: 20220202 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC6433017 |
| DOI: | 10.3201/eid2504.180691 |
| PMID: | 30882318 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1080-6059 |
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| DOI: | 10.3201/eid2504.180691 |