دورية أكاديمية
أعرض في EDS

Attenuated infectious laryngotracheitis virus vaccines differ in their capacity to establish latency in the trigeminal ganglia of specific pathogen free chickens following eye drop inoculation.

التفاصيل البيبلوغرافية
العنوان: Attenuated infectious laryngotracheitis virus vaccines differ in their capacity to establish latency in the trigeminal ganglia of specific pathogen free chickens following eye drop inoculation.
المؤلفون: Thilakarathne DS; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, The University of Melbourne, Parkville, Victoria, Australia., Coppo MJC; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, The University of Melbourne, Parkville, Victoria, Australia., Hartley CA; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, The University of Melbourne, Parkville, Victoria, Australia., Diaz-Méndez A; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, The University of Melbourne, Parkville, Victoria, Australia., Quinteros JA; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, The University of Melbourne, Parkville, Victoria, Australia., Fakhri O; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, The University of Melbourne, Parkville, Victoria, Australia., Vaz PK; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, The University of Melbourne, Parkville, Victoria, Australia., Devlin JM; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, The University of Melbourne, Parkville, Victoria, Australia.
المصدر: PloS one [PLoS One] 2019 Mar 28; Vol. 14 (3), pp. e0213866. Date of Electronic Publication: 2019 Mar 28 (Print Publication: 2019).
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Herpesviridae Infections/*prevention & control , Herpesvirus 1, Gallid/*immunology , Poultry Diseases/*prevention & control , Trigeminal Ganglion/*virology , Vaccines, Attenuated/*immunology, Animals ; Chickens ; DNA, Viral/analysis ; Herpesviridae Infections/virology ; Herpesvirus 1, Gallid/genetics ; Ophthalmic Solutions/chemistry ; Polymerase Chain Reaction ; Poultry Diseases/virology ; Respiratory System/virology ; Specific Pathogen-Free Organisms ; Trachea/virology ; Trigeminal Ganglion/cytology ; Vaccination/methods ; Viral Vaccines/immunology
مستخلص: Infectious laryngotracheitis (ILT) is a respiratory disease that affects chickens. It is caused by the alphaherpesvirus, infectious laryngotracheitis virus (ILTV). This virus undergoes lytic replication in the epithelial cells of the trachea and upper respiratory tract (URT) and establishes latent infection in the trigeminal ganglia (TG) and trachea. Live attenuated vaccines are widely used to control ILT. At least one of these vaccines can establish latent infections in chickens, but this has not been demonstrated for all vaccines. The aim of the current study was to determine the capacity of three commercially available vaccines (SA2, A20 and Serva) and a glycoprotein G deletion mutant vaccine candidate (ΔgG ILTV) to establish latent infection in the TG of specific pathogen free (SPF) chickens. Five groups of 7-day-old SPF chickens were eye-drop vaccinated with either one of the vaccine strains or mock-vaccinated with sterile media and followed until 20 or 21 days post-vaccination (dpv). ILTV DNA was detected at 20-21 dpv in the TG of 23/40 (57.5%) vaccinated SPF chickens (SA2 = 10/10; A20 = 6/10; Serva = 3/10; ΔgG = 4/10) by PCR, but virus could not be reactivated from TG co-cultivated with primary chicken embryo kidney cells. In the birds from which ILTV DNA was detected in the TG, ILTV DNA could not be detected in the URT or trachea of 3 birds in each of the SA2, A20 and Serva vaccinated groups, and in 4 birds in the ΔgG vaccinated group, indicating that these birds were latently infected in the absence of active lytic replication and virus shedding. Results from this study demonstrate the capacity of commercial ILTV vaccines to establish latent infections and underline their importance in the epidemiology of this disease.
Competing Interests: The authors have declared that no competing interests exist.
References: J Gen Virol. 1992 Sep;73 ( Pt 9):2415-20. (PMID: 1328497)
Avian Dis. 2010 Dec;54(4):1251-9. (PMID: 21313847)
J Virol. 1995 Mar;69(3):1389-99. (PMID: 7853471)
Avian Dis. 1969 Feb;13(1):36-45. (PMID: 4304673)
Avian Dis. 2015 Sep;59(3):394-9. (PMID: 26478158)
Avian Pathol. 2011 Aug;40(4):411-7. (PMID: 21812721)
FEMS Microbiol Rev. 2012 May;36(3):684-705. (PMID: 22150699)
Avian Pathol. 1995 Sep;24(3):373-91. (PMID: 18645796)
Bioinformatics. 2012 Jun 15;28(12):1647-9. (PMID: 22543367)
Science. 2012 Jul 13;337(6091):188. (PMID: 22798607)
Proc Natl Acad Sci U S A. 1989 Jun;86(12):4736-40. (PMID: 2543985)
PLoS One. 2015 Mar 18;10(3):e0120282. (PMID: 25785629)
Neuron. 1990 Sep;5(3):353-60. (PMID: 2169271)
Avian Pathol. 2012;41(1):99-106. (PMID: 22845327)
J Gen Virol. 2003 Dec;84(Pt 12):3343-3352. (PMID: 14645915)
Avian Dis. 2007 Dec;51(4):905-11. (PMID: 18251401)
Avian Pathol. 2006 Dec;35(6):449-53. (PMID: 17121733)
J Clin Microbiol. 1996 Jul;34(7):1666-71. (PMID: 8784566)
Virology. 2011 Mar 1;411(1):25-31. (PMID: 21232778)
J Virol. 1991 Aug;65(8):4001-5. (PMID: 1649313)
Avian Dis. 1989 Jul-Sep;33(3):524-30. (PMID: 2549940)
Virology. 1995 Jun 1;209(2):304-14. (PMID: 7778265)
Vaccine. 2007 May 4;25(18):3561-6. (PMID: 17316926)
Avian Dis. 2006 Mar;50(1):50-4. (PMID: 16617981)
J Virol. 1990 Sep;64(9):4288-95. (PMID: 2166818)
J Virol. 2005 Jan;79(2):705-16. (PMID: 15613298)
J Gen Virol. 1989 Sep;70 ( Pt 9):2501-6. (PMID: 2550578)
Avian Dis. 2009 Dec;53(4):574-7. (PMID: 20095159)
Avian Pathol. 2011 Jun;40(3):237-42. (PMID: 21711182)
Pathogens. 2017 Jun 23;6(3):. (PMID: 28644417)
J Virol. 1989 Jun;63(6):2861-5. (PMID: 2542595)
Avian Pathol. 1986;15(3):581-95. (PMID: 18766556)
J Virol Methods. 2008 Aug;151(2):188-93. (PMID: 18584884)
Trop Anim Health Prod. 2015 Aug;47(6):1101-8. (PMID: 25904510)
Infect Genet Evol. 2016 Sep;43:67-73. (PMID: 27223632)
PLoS One. 2013;8(2):e55121. (PMID: 23383306)
J Virol. 1989 Nov;63(11):4976-8. (PMID: 2552180)
J Gen Virol. 2007 Mar;88(Pt 3):732-42. (PMID: 17325345)
Arch Virol. 1991;121(1-4):213-8. (PMID: 1662039)
J Virol. 1989 Jul;63(7):2893-900. (PMID: 2542601)
Avian Dis. 1965 Feb;9(1):44-56. (PMID: 14253995)
Virology. 2009 May 25;388(1):128-36. (PMID: 19328516)
J Virol. 2011 Dec;85(23):12631-7. (PMID: 21937654)
Avian Dis. 2003 Apr-Jun;47(2):261-71. (PMID: 12887186)
J Virol. 1990 Apr;64(4):1630-8. (PMID: 2157048)
Virology. 1995 Jan 10;206(1):633-40. (PMID: 7831818)
Avian Pathol. 2009 Feb;38(1):47-53. (PMID: 19156579)
Virology. 2013 May 25;440(1):64-74. (PMID: 23537957)
Avian Pathol. 2008 Feb;37(1):83-8. (PMID: 18202954)
Avian Dis. 1991 Apr-Jun;35(2):348-55. (PMID: 1649591)
J Gen Virol. 2006 Oct;87(Pt 10):2839-47. (PMID: 16963741)
Virology. 1988 Jan;162(1):251-4. (PMID: 2827384)
J Gen Virol. 2010 Apr;91(Pt 4):847-57. (PMID: 19940061)
J Virol. 1990 Nov;64(11):5396-402. (PMID: 2170678)
J Virol. 1992 Apr;66(4):2150-6. (PMID: 1312625)
المشرفين على المادة: 0 (DNA, Viral)
0 (Ophthalmic Solutions)
0 (Vaccines, Attenuated)
0 (Viral Vaccines)
تواريخ الأحداث: Date Created: 20190329 Date Completed: 20191209 Latest Revision: 20200309
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC6438565
DOI: 10.1371/journal.pone.0213866
PMID: 30921344
قاعدة البيانات: MEDLINE
الوصف
تدمد:1932-6203
DOI:10.1371/journal.pone.0213866