دورية أكاديمية
Bioprinting a Synthetic Smectic Clay for Orthopedic Applications.
| العنوان: | Bioprinting a Synthetic Smectic Clay for Orthopedic Applications. |
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| المؤلفون: | Afewerki S; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.; Harvard-MIT Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Magalhães LSSM; LIMAV Interdisciplinary Laboratory for Advanced Materials, Department of Materials Engineering, UFPI-Federal University of Piauí, Teresina, PI, 64049-550, Brazil., Silva ADR; Air Force Academy, Pirassununga, São Paulo, 13631-972, Brazil., Stocco TD; Faculty of Medical Sciences, State University of Campinas, Rua Tessália Vieira de Camargo, 126. Cidade Universitária Zeferino Vaz. Campinas, São Paulo, 13083-887, Brazil.; Faculty of Physiotherapy, Santo Amaro University, São Paulo, 04829-300, Brazil., Silva Filho EC; LIMAV Interdisciplinary Laboratory for Advanced Materials, Department of Materials Engineering, UFPI-Federal University of Piauí, Teresina, PI, 64049-550, Brazil., Marciano FR; Scientifical and Technological Institute, Brasil University, 08230-030, Itaquera, São Paulo, Brazil., Lobo AO; LIMAV Interdisciplinary Laboratory for Advanced Materials, Department of Materials Engineering, UFPI-Federal University of Piauí, Teresina, PI, 64049-550, Brazil. |
| المصدر: | Advanced healthcare materials [Adv Healthc Mater] 2019 Jul; Vol. 8 (13), pp. e1900158. Date of Electronic Publication: 2019 Apr 08. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101581613 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2192-2659 (Electronic) Linking ISSN: 21922640 NLM ISO Abbreviation: Adv Healthc Mater Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Weinheim : Wiley-VCH, 2012- |
| مواضيع طبية MeSH: | Bioprinting/*methods , Musculoskeletal Diseases/*therapy , Silicates/*therapeutic use, Biocompatible Materials/chemistry ; Biocompatible Materials/therapeutic use ; Bone Substitutes/chemistry ; Bone Substitutes/therapeutic use ; Humans ; Musculoskeletal Diseases/pathology ; Nanoparticles/chemistry ; Printing, Three-Dimensional ; Silicates/chemistry ; Tissue Engineering ; Tissue Scaffolds/chemistry |
| مستخلص: | Bioprinting technology has emerged as an important approach to bone and cartilage tissue engineering applications, because it allows the printing of scaffolds loaded with various components, such as cells, growth factors, or drugs. In this context, the bone has a very complex architecture containing highly vascularized and calcified tissues, while cartilage is avascular and has low cellularity and few nutrients. Owing to this complexity, the repair and regeneration of these tissues are highly challenging. Identification of the appropriate biomaterial and fabrication technologies can provide sustainable solutions to this challenge. Here, nanosized Laponite ® (Laponite is a trademark of the company BYK Additives Ltd.) has shown to be a promising material due to its unique properties such as excellent biocompatibility, facile gel formation, shear-thinning property (reversible physical crosslinking), high specific surface area, degrade into nontoxic products, and with osteoinductive properties. Even though Laponite and Laponite-based composite for 3D bioprinting application are considered as soft gels, they may therefore not be thought exhibiting sufficient mechanical strength for orthopedic applications. However, through the merging with suitable composite and, also by incorporation of crosslinking step, desired mechanical strength for orthopedic application can be obtained. In this review, recent advances and future perspective of bioprinting Laponite and Laponite composites for orthopedic applications are highlighted. (© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.) |
| معلومات مُعتمدة: | 303752/2017-3 International National Council for Scientific and Technological Development; 304133/2017-5 International National Council for Scientific and Technological Development; Serra-1709-19479 International Serrapilheira Institute; International Sweden-America Foundation; International Olle Engkvist byggmästare Foundation; International National Council for Scientific and Technological Development |
| فهرسة مساهمة: | Keywords: bioprinters; bones; cartilage; synthetic smectic clays; tissue engineering |
| المشرفين على المادة: | 0 (Biocompatible Materials) 0 (Bone Substitutes) 0 (Silicates) D703131383 (laponite) |
| تواريخ الأحداث: | Date Created: 20190409 Date Completed: 20200812 Latest Revision: 20200812 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1002/adhm.201900158 |
| PMID: | 30957992 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2192-2659 |
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| DOI: | 10.1002/adhm.201900158 |