دورية أكاديمية
An Asymmetric Opening of HIV-1 Envelope Mediates Antibody-Dependent Cellular Cytotoxicity.
العنوان: | An Asymmetric Opening of HIV-1 Envelope Mediates Antibody-Dependent Cellular Cytotoxicity. |
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المؤلفون: | Alsahafi N; Centre de Recherche du CHUM, Montreal, QC, Canada; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada., Bakouche N; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, USA., Kazemi M; Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia., Richard J; Centre de Recherche du CHUM, Montreal, QC, Canada; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada., Ding S; Centre de Recherche du CHUM, Montreal, QC, Canada; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada., Bhattacharyya S; Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia., Das D; Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia., Anand SP; Centre de Recherche du CHUM, Montreal, QC, Canada; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada., Prévost J; Centre de Recherche du CHUM, Montreal, QC, Canada; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada., Tolbert WD; Infectious Diseases Division, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Lu H; Aaron Diamond AIDS Research Center, Affiliate of The Rockefeller University, New York, NY, USA., Medjahed H; Centre de Recherche du CHUM, Montreal, QC, Canada., Gendron-Lepage G; Centre de Recherche du CHUM, Montreal, QC, Canada., Ortega Delgado GG; Centre de Recherche du CHUM, Montreal, QC, Canada., Kirk S; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104-6323, USA., Melillo B; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104-6323, USA., Mothes W; Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06536, USA., Sodroski J; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Smith AB 3rd; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104-6323, USA., Kaufmann DE; Centre de Recherche du CHUM, Montreal, QC, Canada; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada; Department of Medicine, Université de Montréal, Montreal, QC, Canada; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA., Wu X; Aaron Diamond AIDS Research Center, Affiliate of The Rockefeller University, New York, NY, USA., Pazgier M; Infectious Diseases Division, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Rouiller I; Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia. Electronic address: isabelle.rouiller@unimelb.edu.au., Finzi A; Centre de Recherche du CHUM, Montreal, QC, Canada; Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, QC, Canada. Electronic address: andres.finzi@umontreal.ca., Munro JB; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, USA. Electronic address: james.munro@tufts.edu. |
المصدر: | Cell host & microbe [Cell Host Microbe] 2019 Apr 10; Vol. 25 (4), pp. 578-587.e5. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Cell Press Country of Publication: United States NLM ID: 101302316 Publication Model: Print Cited Medium: Internet ISSN: 1934-6069 (Electronic) Linking ISSN: 19313128 NLM ISO Abbreviation: Cell Host Microbe Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Cambridge, Mass. : Cell Press |
مواضيع طبية MeSH: | Antibody-Dependent Cell Cytotoxicity*, CD4-Positive T-Lymphocytes/*virology , HIV Antibodies/*immunology , HIV-1/*immunology , env Gene Products, Human Immunodeficiency Virus/*immunology, CD4 Antigens/metabolism ; Cells, Cultured ; Humans ; Protein Binding ; Protein Conformation ; env Gene Products, Human Immunodeficiency Virus/chemistry |
مستخلص: | The HIV-1 envelope glycoprotein (Env) (gp120-gp41) (Copyright © 2019 Elsevier Inc. All rights reserved.) |
التعليقات: | Comment in: Cell Host Microbe. 2019 Jun 12;25(6):767-768. doi: 10.1016/j.chom.2019.05.009. (PMID: 31194935) |
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معلومات مُعتمدة: | UM1 AI100663 United States AI NIAID NIH HHS; R01 AI129769 United States AI NIAID NIH HHS; P01 GM056550 United States GM NIGMS NIH HHS; HHSN261200800001C United States CA NCI NIH HHS; R01 AI124982 United States AI NIAID NIH HHS; R01 AI122953 United States AI NIAID NIH HHS; R01 AI116274 United States AI NIAID NIH HHS; HHSN261200800001E United States CA NCI NIH HHS; K22 AI116262 United States AI NIAID NIH HHS |
فهرسة مساهمة: | Keywords: 17b; A32; ADCC; CD4i Abs; HIV-1; State 2A; cryo-EM; envelope glycoproteins; smFRET |
المشرفين على المادة: | 0 (CD4 Antigens) 0 (HIV Antibodies) 0 (env Gene Products, Human Immunodeficiency Virus) |
تواريخ الأحداث: | Date Created: 20190412 Date Completed: 20191121 Latest Revision: 20240615 |
رمز التحديث: | 20240615 |
مُعرف محوري في PubMed: | PMC6592637 |
DOI: | 10.1016/j.chom.2019.03.002 |
PMID: | 30974085 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1934-6069 |
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DOI: | 10.1016/j.chom.2019.03.002 |