دورية أكاديمية
أعرض في EDS

Peripheral neuropathy induced by drinking water contaminated with low-dose arsenic in Myanmar.

التفاصيل البيبلوغرافية
العنوان: Peripheral neuropathy induced by drinking water contaminated with low-dose arsenic in Myanmar.
المؤلفون: Mochizuki H; Division of Neurology, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan. mochizuki-h@umin.net., Phyu KP; Department of Medical Research, Ministry of Health and Sports, Yangon, Myanmar., Aung MN; Department of Medical Research, Ministry of Health and Sports, Yangon, Myanmar., Zin PW; Department of Medical Research, Ministry of Health and Sports, Yangon, Myanmar., Yano Y; Center for International Relations, University of Miyazaki, Miyazaki, Japan., Myint MZ; Department of Neurology, Yangon General Hospital, Yangon, Myanmar., Thit WM; Department of Neurology, Yangon General Hospital, Yangon, Myanmar., Yamamoto Y; Department of Public Health, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan., Hishikawa Y; Department of Anatomy, Histochemistry and Cell Biology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan., Thant KZ; Department of Medical Research, Ministry of Health and Sports, Yangon, Myanmar., Maruyama M; Department of Applied Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan., Kuroda Y; Department of Public Health, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
المصدر: Environmental health and preventive medicine [Environ Health Prev Med] 2019 Apr 23; Vol. 24 (1), pp. 23. Date of Electronic Publication: 2019 Apr 23.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Japanese Society for Hygiene Country of Publication: Japan NLM ID: 9609642 Publication Model: Electronic Cited Medium: Internet ISSN: 1347-4715 (Electronic) Linking ISSN: 1342078X NLM ISO Abbreviation: Environ Health Prev Med Subsets: MEDLINE
أسماء مطبوعة: Publication: 2022- : [Kyoto, Japan] : Japanese Society for Hygiene
Original Publication: Sapporo, Japan : Japanese Society for Hygiene, c1996-
مواضيع طبية MeSH: Arsenic/*toxicity , Dietary Exposure/*adverse effects , Drinking Water/*adverse effects , Drinking Water/*chemistry , Peripheral Nervous System Diseases/*chemically induced , Water Pollutants, Chemical/*toxicity, Adolescent ; Adult ; Arsenic/analysis ; Cross-Sectional Studies ; Dose-Response Relationship, Drug ; Female ; Groundwater/chemistry ; Humans ; Male ; Middle Aged ; Myanmar/epidemiology ; Peripheral Nervous System Diseases/epidemiology ; Peripheral Nervous System Diseases/physiopathology ; Sensation Disorders/chemically induced ; Sensation Disorders/epidemiology ; Sensation Disorders/physiopathology ; Water Pollutants, Chemical/analysis ; Young Adult
مستخلص: Background: More than 140 million people drink arsenic-contaminated groundwater. It is unknown how much arsenic exposure is necessary to cause neurological impairment. Here, we evaluate the relationship between neurological impairments and the arsenic concentration in drinking water (ACDW).
Participants and Methods: A cross-sectional study design was employed. We performed medical examinations of 1867 residents in seven villages in the Thabaung township in Myanmar. Medical examinations consisted of interviews regarding subjective neurological symptoms and objective neurological examinations of sensory disturbances. For subjective neurological symptoms, we ascertained the presence or absence of defects in smell, vision, taste, and hearing; the feeling of weakness; and chronic numbness or pain. For objective sensory disturbances, we examined defects in pain sensation, vibration sensation, and two-point discrimination. We analyzed the relationship between the subjective symptoms, objective sensory disturbances, and ACDW.
Results: Residents with ACDW ≥ 10 parts per billion (ppb) had experienced a "feeling of weakness" and "chronic numbness or pain" significantly more often than those with ACDW < 10 ppb. Residents with ACDW ≥ 50 ppb had three types of sensory disturbances significantly more often than those with ACDW < 50 ppb. In children, there was no significant association between symptoms or signs and ACDW.
Conclusion: Subjective symptoms, probably due to peripheral neuropathy, occurred at very low ACDW (around 10 ppb). Objective peripheral nerve disturbances of both small and large fibers occurred at low ACDW (> 50 ppb). These data suggest a threshold for the occurrence of peripheral neuropathy due to arsenic exposure, and indicate that the arsenic concentration in drinking water should be less than 10 ppb to ensure human health.
References: Am J Epidemiol. 2000 Mar 15;151(6):554-65. (PMID: 10733037)
J Toxicol Clin Toxicol. 2001;39(7):683-700. (PMID: 11778666)
J Environ Sci Health A Tox Hazard Subst Environ Eng. 2003 Jan;38(1):87-113. (PMID: 12635821)
J Environ Sci Health A Tox Hazard Subst Environ Eng. 2003 Jan;38(1):165-83. (PMID: 12635825)
Sci Total Environ. 2003 Sep 1;313(1-3):213-26. (PMID: 12922072)
Psychol Bull. 1960 Jul;57:318-28. (PMID: 14440422)
Toxicol Appl Pharmacol. 2004 Aug 1;198(3):243-52. (PMID: 15276403)
Am J Public Health. 2004 Nov;94(11):1936-7. (PMID: 15514231)
J Epidemiol. 2006 Sep;16(5):207-13. (PMID: 16951540)
Epidemiology. 2007 Jan;18(1):44-51. (PMID: 17149142)
J Health Popul Nutr. 2006 Sep;24(3):277-81. (PMID: 17366769)
Environ Health Perspect. 2007 Feb;115(2):285-9. (PMID: 17384779)
Environ Health Perspect. 2007 Apr;115(4):648-52. (PMID: 17450238)
Indian J Med Res. 2008 Oct;128(4):436-47. (PMID: 19106439)
Leuk Res. 2010 Mar;34(3):403-5. (PMID: 19733394)
Int J Diabetes Dev Ctries. 2008 Jul;28(3):71-8. (PMID: 19902038)
Environ Health. 2011 Jul 08;10:64. (PMID: 21740555)
Kaohsiung J Med Sci. 2011 Sep;27(9):360-70. (PMID: 21914522)
JAMA. 2013 Nov 27;310(20):2191-4. (PMID: 24141714)
Sci Total Environ. 2014 Apr 15;478:21-4. (PMID: 24530581)
Ann Glob Health. 2014 Jul-Aug;80(4):303-14. (PMID: 25459332)
Ecotoxicol Environ Saf. 2015 Feb;112:247-70. (PMID: 25463877)
Environ Res. 2015 Feb;137:329-37. (PMID: 25601736)
Interdiscip Toxicol. 2014 Jun;7(2):60-72. (PMID: 26109881)
Environ Sci Technol. 2016 Apr 5;50(7):3521-9. (PMID: 26788939)
J Neurol Sci. 2016 Feb 15;361:39-42. (PMID: 26810514)
Environ Sci Pollut Res Int. 2016 May;23(10):9492-504. (PMID: 26838039)
J Cell Biochem. 2018 Jan;119(1):157-184. (PMID: 28643849)
Environ Health Prev Med. 2017 May 11;22(1):45. (PMID: 29165156)
Arch Environ Contam Toxicol. 2018 Nov;75(4):521-529. (PMID: 29974180)
J Neurol Sci. 2019 Mar 15;398:2-3. (PMID: 30658225)
Sci Total Environ. 1983 Jul;29(1-2):171-5. (PMID: 6612324)
معلومات مُعتمدة: 18K10052 JSPS KAKENHI
فهرسة مساهمة: Keywords: Arsenic; Groundwater; Peripheral neuropathy; Pollution; Sensory disturbance
المشرفين على المادة: 0 (Drinking Water)
0 (Water Pollutants, Chemical)
N712M78A8G (Arsenic)
تواريخ الأحداث: Date Created: 20190425 Date Completed: 20190909 Latest Revision: 20200225
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC6480850
DOI: 10.1186/s12199-019-0781-0
PMID: 31014238
قاعدة البيانات: MEDLINE
الوصف
تدمد:1347-4715
DOI:10.1186/s12199-019-0781-0