دورية أكاديمية
Prevalence of human papillomavirus, human immunodeficiency virus and other sexually transmitted infections among female sex workers in Togo: a national cross-sectional survey.
| العنوان: | Prevalence of human papillomavirus, human immunodeficiency virus and other sexually transmitted infections among female sex workers in Togo: a national cross-sectional survey. |
|---|---|
| المؤلفون: | Ferré VM; Université de Paris, IAME, INSERM, F-75018 Paris, France; AP-HP, Hôpital Bichat, DEBRC, F-75018 Paris, France., Ekouevi DK; Université de Lomé, Faculté des Sciences de la Santé, Département de Santé Publique, Lomé, Togo; Centre Africain de Recherche en Epidémiologie et en Santé Publique (CARESP), Lomé, Togo; ISPED, Université de Bordeaux & Centre INSERM U1219 - Bordeaux Population Health, Bordeaux, France., Gbeasor-Komlanvi FA; Université de Lomé, Faculté des Sciences de la Santé, Département de Santé Publique, Lomé, Togo; Centre Africain de Recherche en Epidémiologie et en Santé Publique (CARESP), Lomé, Togo., Collin G; Université de Paris, IAME, INSERM, F-75018 Paris, France; AP-HP, Hôpital Bichat, DEBRC, F-75018 Paris, France., Le Hingrat Q; Université de Paris, IAME, INSERM, F-75018 Paris, France; AP-HP, Hôpital Bichat, DEBRC, F-75018 Paris, France., Tchounga B; Programme PACCI, site ANRS, Abidjan, Cote d'Ivoire., Salou M; Université de Lomé, Centre de Biologie Moléculaire et d'Immunologie, Lomé, Togo., Descamps D; Université de Paris, IAME, INSERM, F-75018 Paris, France; AP-HP, Hôpital Bichat, DEBRC, F-75018 Paris, France., Charpentier C; Université de Paris, IAME, INSERM, F-75018 Paris, France; AP-HP, Hôpital Bichat, DEBRC, F-75018 Paris, France. Electronic address: charlotte.charpentier@aphp.fr., Dagnra AC; Université de Lomé, Centre de Biologie Moléculaire et d'Immunologie, Lomé, Togo; Programme national de lutte contre le sida et les infections sexuellement transmissibles, Lomé, Togo. |
| المصدر: | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2019 Dec; Vol. 25 (12), pp. 1560.e1-1560.e7. Date of Electronic Publication: 2019 Apr 30. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 9516420 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-0691 (Electronic) Linking ISSN: 1198743X NLM ISO Abbreviation: Clin Microbiol Infect Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2015- : London : Elsevier Original Publication: Paris : Decker Europe, c1995- |
| مواضيع طبية MeSH: | Sex Workers*, HIV/*isolation & purification , Papillomaviridae/*isolation & purification , Sexually Transmitted Diseases/*diagnosis , Sexually Transmitted Diseases/*epidemiology, Adult ; Anal Canal/microbiology ; Anal Canal/parasitology ; Anal Canal/virology ; Cervix Uteri/microbiology ; Cervix Uteri/parasitology ; Cervix Uteri/virology ; Coinfection/diagnosis ; Coinfection/epidemiology ; Cross-Sectional Studies ; Female ; HIV Infections/diagnosis ; HIV Infections/epidemiology ; Humans ; Papillomaviridae/classification ; Papillomaviridae/genetics ; Papillomavirus Infections/diagnosis ; Papillomavirus Infections/epidemiology ; Prevalence ; Serologic Tests ; Togo/epidemiology ; Young Adult |
| مستخلص: | Objectives: Sub-Saharan Africa is a region with high incidence of both human immunodeficiency virus (HIV) and cervical cancer. We conducted the first national study in Togo to assess prevalence of human papillomavirus (HPV), HIV and other sexually transmitted infections (STIs) among female sex workers (FSW). Methods: A multicentric cross-sectional study was conducted among FSW recruited in hot spots (clubs, streets) in four Togolese cities. HPV and STIs were tested from cervical and anal swabs. HIV and syphilis were screened with rapid tests. Results: In all, 310 FSW were recruited; HIV and cervical high-risk HPV (hrHPV) prevalence were 10.6% (33/310) and 32.9% (102/310), respectively. The most frequent hrHPV types were HPV58 (13.6%, 19/140), HPV35 (12.9%, 18/140), HPV31 (12.1%, 17/140) and HPV16 (10.7%, 15/140). Prevalence of hrHPV and multiple hrHPV infections showed higher rates in HIV-positive than in HIV-negative FSW (48.5% versus 31.0%, p 0.04 and 21.2% versus 9.0%, p 0.03; respectively). Prevalence of hrHPV was higher in cervical than anal swabs (34.1% versus 20.7%, p 0.0004). High-risk HPV anal infections were more frequent among HIV-positive than HIV-negative FSW (51.9% versus 17.3%, p 2 × 10 -5 ). Concomitant anal and cervical hrHPV infections were present in 43.2% (41/95) of hrHPV-positive FSW. Overall prevalence in the cervix of Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium and Trichomonas vaginalis were 4.2%, 6.1%, 5.5% and 6.5%, respectively. Conclusions: This first African study on paired cervical and anal samples showed a high prevalence of genital HPV infections with a rather high rate of concomitant HPV infections but low type concordance. We report an unusual distribution of hrHPV types. These findings highlight the critical need for implementation of a national HPV vaccination strategy. (Copyright © 2019 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Female sex workers; Human immunodeficiency virus; Human papillomavirus; Sexually transmitted infections; Togo |
| تواريخ الأحداث: | Date Created: 20190504 Date Completed: 20200325 Latest Revision: 20200325 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.cmi.2019.04.015 |
| PMID: | 31051265 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1469-0691 |
|---|---|
| DOI: | 10.1016/j.cmi.2019.04.015 |