دورية أكاديمية
Benzodiazepine use among older adults with schizophrenia spectrum disorder: prevalence and associated factors in a multicenter study.
| العنوان: | Benzodiazepine use among older adults with schizophrenia spectrum disorder: prevalence and associated factors in a multicenter study. |
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| المؤلفون: | Schuster JP; Old-Age Psychiatry Service, Lausanne University Hospital, Lausanne, Switzerland., Hoertel N; Department of Psychiatry, AP-HP, Western Paris University Hospitals, 92130 Issy-les-Moulineaux, France.; INSERM UMR 894, Psychiatry and Neurosciences Center, Paris, France.; Paris Descartes University, Sorbonne Paris Cité, Paris, France., von Gunten A; Old-Age Psychiatry Service, Lausanne University Hospital, Lausanne, Switzerland., Seigneurie AS; Department of Psychiatry, AP-HP, Western Paris University Hospitals, 92130 Issy-les-Moulineaux, France., Limosin F; Department of Psychiatry, AP-HP, Western Paris University Hospitals, 92130 Issy-les-Moulineaux, France.; INSERM UMR 894, Psychiatry and Neurosciences Center, Paris, France.; Paris Descartes University, Sorbonne Paris Cité, Paris, France. |
| مؤلفون مشاركون: | CSA Study group |
| المصدر: | International psychogeriatrics [Int Psychogeriatr] 2020 Apr; Vol. 32 (4), pp. 441-451. Date of Electronic Publication: 2019 May 07. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cambridge University Press Country of Publication: England NLM ID: 9007918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1741-203X (Electronic) Linking ISSN: 10416102 NLM ISO Abbreviation: Int Psychogeriatr Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2004- : Cambridge, UK : Cambridge University Press Original Publication: New York : Springer Pub. Co., c1989- |
| مواضيع طبية MeSH: | Antipsychotic Agents/*therapeutic use , Benzodiazepines/*therapeutic use , Schizophrenia/*drug therapy, Aged ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Prevalence ; Quality of Life ; Schizophrenia/epidemiology |
| مستخلص: | Objectives: Data on psychotropic medications of older patients with schizophrenia spectrum disorder are scarce. Specifically, information about the use of benzodiazepines among older patients with schizophrenia spectrum disorder is very limited. Because benzodiazepine use in older patients has been associated with many disabling side effects, its use in actual practice must be described and questioned. This study aimed at exploring the prevalence of benzodiazepine use and the clinical factors associated with such use among older patients with schizophrenia spectrum disorder. Methods/design: Data from the Cohort of individuals with Schizophrenia Aged 55 years or more (CSA) were used to examine the prevalence of benzodiazepine use among older patients with schizophrenia spectrum disorder. Demographic and clinical characteristics associated with benzodiazepine prescription were also explored. Results: The prevalence of benzodiazepine use was 29.8% of older patients with schizophrenia spectrum disorder. These patients were significantly more likely to have medical comorbidities, cognitive and social functioning impairments, to report a lifetime history of suicide attempt, to be institutionalized, and to have been hospitalized in a psychiatric service in the past year compared to those without a benzodiazepine prescription (all p<0.05). There were no between-group differences in schizophrenia severity and psychiatric comorbidity. Conclusions: Although it can be hypothesized that benzodiazepine prescription is part of a short-term therapeutic strategy toward patients with more severe trouble or comorbid disorders, our results suggest a strong link between benzodiazepine prescription and a particularly vulnerable subpopulation of older patients with schizophrenia spectrum disorder. |
| التعليقات: | Comment in: Int Psychogeriatr. 2020 Apr;32(4):419-422. (PMID: 32295671) |
| فهرسة مساهمة: | Keywords: benzodiazepines; elderly; schizophrenia; treatment |
| المشرفين على المادة: | 0 (Antipsychotic Agents) 12794-10-4 (Benzodiazepines) |
| تواريخ الأحداث: | Date Created: 20190508 Date Completed: 20210412 Latest Revision: 20210412 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1017/S1041610219000358 |
| PMID: | 31062670 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1741-203X |
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| DOI: | 10.1017/S1041610219000358 |