دورية أكاديمية
Association between Early Resistive Index Measurement and Early Graft Function and Long-Term Graft Survival after Kidney Transplantation: an Evidence-based Clinical Review.
| العنوان: | Association between Early Resistive Index Measurement and Early Graft Function and Long-Term Graft Survival after Kidney Transplantation: an Evidence-based Clinical Review. |
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| المؤلفون: | Tirtayasa PMW; Division of Urology, Department of Surgery, Faculty of Medicine Universitas Udayana / Sanglah Hospital, Bali, Indonesia. wisnu.tirtayasa@gmail.com., Duarsa GWK, Situmorang GR, Yudiana IW, Santosa KB, Oka AAG, Rodjani A, Rasyid N |
| المصدر: | Acta medica Indonesiana [Acta Med Indones] 2019 Jan; Vol. 51 (1), pp. 77-85. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Indonesian Society of Internal Medicine Country of Publication: Indonesia NLM ID: 7901042 Publication Model: Print Cited Medium: Internet ISSN: 0125-9326 (Print) Linking ISSN: 01259326 NLM ISO Abbreviation: Acta Med Indones Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Jakarta, Indonesia : Indonesian Society of Internal Medicine |
| مواضيع طبية MeSH: | Graft Survival* , Kidney Transplantation* , Vascular Resistance*, Delayed Graft Function/*diagnostic imaging , Graft Rejection/*diagnostic imaging , Kidney/*diagnostic imaging, Delayed Graft Function/physiopathology ; Graft Rejection/physiopathology ; Humans ; Kidney/physiopathology ; Postoperative Complications/diagnostic imaging ; Postoperative Complications/physiopathology ; Ultrasonography, Doppler |
| مستخلص: | Background: resistive index (RI) is highly utilised to assess the graft function using Doppler ultrasonography. The RI has been shown as the best ultrasound parameter to assess kidney allograft dysfunction. Several studies have established the role of the RI as a predictor of transplant failure. However, these studies were using RI measurement in the later stages post transplantation. The present study has conducted to identify the association between early RI measurement and early graft function represented as delayed graft function (DGF) and immediate graft function (IGF), as well as long-term graft survival. Methods: an evidence-based clinical review of studies published before May 2018 was conducted from Medline, Science Direct, EMBASE and Cochrane databases. Studies on early measurement of RI whereby the primary or secondary goals of the study related to graft function and/or graft survival were included. Studies using late RI measurement and without RI value groups were excluded. The Mantzel-Haenzel method was used to analyse pooled risk ratio and 95% confidence interval, while the heterogeneity of the study was calculated through I2 value. Data analysis was performed using Review Manager 5.3. Results: nine studies with a total of 1802 patients who had undergone a kidney transplant were analysed. DGF was found in 19% (193/1015) of the low RI group and in 42.8% (337/787) of the high RI group (RR 2.04 (95% CI 1.72 - 2.41), p < 0.00001, I2 = 28%). IGF was found in 39.5% (62/157) of the low RI group and in 10.5% (28/268) of the high RI group (RR 0.26 (95% CI 0.17 - 0.40), p < 0.00001, I2 = 0%). Long-term graft survival, with follow up between 60-144 months, was found in 83% (701/845) of the low RI group and in 69.4% (395/569) of the high RI group (RR 0.82 (95% CI 0.72 - 0.93), p = 0.002, I2 = 63%). Conclusion: the results of this study emphasise the association between early measurement of RI and early graft function, and long-term graft survival. An elevated RI provides the chance of recognizing the patients with poor long-term prognosis, from the first moment after kidney transplant. |
| فهرسة مساهمة: | Keywords: graft function; kidney transplant; resistive index |
| تواريخ الأحداث: | Date Created: 20190511 Date Completed: 20191129 Latest Revision: 20191129 |
| رمز التحديث: | 20221213 |
| PMID: | 31073112 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0125-9326 |
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