تقرير
Preclinical evidence for an effective therapeutic activity of FL118, a novel survivin inhibitor, in patients with relapsed/refractory multiple myeloma.
| العنوان: | Preclinical evidence for an effective therapeutic activity of FL118, a novel survivin inhibitor, in patients with relapsed/refractory multiple myeloma. |
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| المؤلفون: | Holthof LC; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., van der Horst HJ; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., van Hal-van Veen SE; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., Ruiter RWJ; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., Li F; Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center, New York, NJ USA., Buijze M; Department of Otolaryngology-Head and Neck Surgery, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., Andersen MN; Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Department of Hematology, Aarhus University Hospital, Aarhus, Denmark., Yuan H; Kuros Biosciences BV, Bilthoven, the Netherlands., de Bruijn J; Kuros Biosciences BV, Bilthoven, the Netherlands.; The School of Engineering and Materials Science, Queen Mary University of London, London, UK., van de Donk NWCJ; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., Lokhorst HM; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., Zweegman S; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., Groen RWJ; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands t.mutis@vumc.nl r.groen@vumc.nl., Mutis T; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands t.mutis@vumc.nl r.groen@vumc.nl. |
| المصدر: | Haematologica [Haematologica] 2020 Jan 31; Vol. 105 (2), pp. e80-e83. Date of Electronic Publication: 2020 Jan 31 (Print Publication: 2020). |
| نوع المنشور: | Letter; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 1999- : Pavia, Italy : Ferrata Storti Foundation Original Publication: Pavia [etc.] |
| مواضيع طبية MeSH: | Indolizines* , Multiple Myeloma*/drug therapy, Survivin/*antagonists & inhibitors, Benzodioxoles ; Humans |
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| المشرفين على المادة: | 0 (7-ethyl-7-hydroxy-10H-1,3-Dioxolo(4,5-g)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-8,11(7H,12H)-dione) 0 (Benzodioxoles) 0 (Indolizines) 0 (Survivin) |
| تواريخ الأحداث: | Date Created: 20190525 Date Completed: 20210427 Latest Revision: 20220531 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC7012462 |
| DOI: | 10.3324/haematol.2018.213314 |
| PMID: | 31123033 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1592-8721 |
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| DOI: | 10.3324/haematol.2018.213314 |