تقرير
Preclinical evidence for an effective therapeutic activity of FL118, a novel survivin inhibitor, in patients with relapsed/refractory multiple myeloma.
العنوان: | Preclinical evidence for an effective therapeutic activity of FL118, a novel survivin inhibitor, in patients with relapsed/refractory multiple myeloma. |
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المؤلفون: | Holthof LC; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., van der Horst HJ; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., van Hal-van Veen SE; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., Ruiter RWJ; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., Li F; Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center, New York, NJ USA., Buijze M; Department of Otolaryngology-Head and Neck Surgery, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., Andersen MN; Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark.; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Department of Hematology, Aarhus University Hospital, Aarhus, Denmark., Yuan H; Kuros Biosciences BV, Bilthoven, the Netherlands., de Bruijn J; Kuros Biosciences BV, Bilthoven, the Netherlands.; The School of Engineering and Materials Science, Queen Mary University of London, London, UK., van de Donk NWCJ; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., Lokhorst HM; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., Zweegman S; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands., Groen RWJ; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands t.mutis@vumc.nl r.groen@vumc.nl., Mutis T; Department of Hematology, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, Amsterdam, the Netherlands t.mutis@vumc.nl r.groen@vumc.nl. |
المصدر: | Haematologica [Haematologica] 2020 Jan 31; Vol. 105 (2), pp. e80-e83. Date of Electronic Publication: 2020 Jan 31 (Print Publication: 2020). |
نوع المنشور: | Letter; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 1999- : Pavia, Italy : Ferrata Storti Foundation Original Publication: Pavia [etc.] |
مواضيع طبية MeSH: | Indolizines* , Multiple Myeloma*/drug therapy, Survivin/*antagonists & inhibitors, Benzodioxoles ; Humans |
References: | Nat Med. 2010 Apr;16(4):483-9. (PMID: 20228816) Mol Cancer Res. 2008 Aug;6(8):1356-64. (PMID: 18708367) Clin Cancer Res. 2013 Oct 15;19(20):5591-601. (PMID: 24004671) Am J Hematol. 2006 Nov;81(11):824-31. (PMID: 16929535) Int Rev Cell Mol Biol. 2013;305:217-52. (PMID: 23890383) Haematologica. 2011 Feb;96(2):284-90. (PMID: 21109694) Oncotarget. 2016 Sep 13;7(37):60698-60711. (PMID: 27474171) Am J Transl Res. 2015 Oct 15;7(10):1765-81. (PMID: 26692923) Blood. 2012 Jul 19;120(3):e9-e16. (PMID: 22653974) Blood. 2017 Apr 6;129(14):1969-1979. (PMID: 28151428) PLoS One. 2012;7(9):e45571. (PMID: 23029106) Mol Cancer. 2015 Apr 28;14:92. (PMID: 25928015) Blood Rev. 2017 Jul;31(4):251-259. (PMID: 28284458) Blood Cancer J. 2017 Sep 15;7(9):e610. (PMID: 29016571) J Exp Clin Cancer Res. 2018 Oct 3;37(1):240. (PMID: 30285798) |
المشرفين على المادة: | 0 (7-ethyl-7-hydroxy-10H-1,3-Dioxolo(4,5-g)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-8,11(7H,12H)-dione) 0 (Benzodioxoles) 0 (Indolizines) 0 (Survivin) |
تواريخ الأحداث: | Date Created: 20190525 Date Completed: 20210427 Latest Revision: 20220531 |
رمز التحديث: | 20221213 |
مُعرف محوري في PubMed: | PMC7012462 |
DOI: | 10.3324/haematol.2018.213314 |
PMID: | 31123033 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1592-8721 |
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DOI: | 10.3324/haematol.2018.213314 |