دورية أكاديمية
أعرض في EDS

The Role of Cardiac Magnetic Resonance Imaging in Severe Anorexia Nervosa.

التفاصيل البيبلوغرافية
العنوان: The Role of Cardiac Magnetic Resonance Imaging in Severe Anorexia Nervosa.
المؤلفون: Chu K; Internal Medicine, University of Manitoba, Winnipeg, CAN., Asselin CY; Cardiology, University of Manitoba, Winnipeg, CAN., Buffo I; Pediatrics, University of Manitoba, Winnipeg, CAN., Lane M; Psychiatry, University of Manitoba, Winnipeg, CAN., Ludwig L; Psychiatry, University of Manitoba, Winnipeg, CAN., Jassal DS; Internal Medicine, University of Manitoba, Winnipeg, CAN., Schantz D; Pediatrics, University of Manitoba, Winnipeg, CAN.
المصدر: Cureus [Cureus] 2019 Mar 11; Vol. 11 (3), pp. e4229. Date of Electronic Publication: 2019 Mar 11.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: Electronic Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Palo Alto, CA : Cureus, Inc.
مستخلص: Objective Anorexia nervosa (AN) patients are at an increased risk of developing cardiac complications including bradyarrhythmias, systolic dysfunction, pericardial effusions, and sudden cardiac death. Although previous echocardiographic studies in AN patients have demonstrated a reduction in overall left ventricular (LV) mass, systolic dysfunction, and silent pericardial effusions, little is known about the role of cardiac magnetic resonance imaging (CMR) in assessing this patient population. The objective of this study was to assess cardiac indices and the presence of myocardial fibrosis in AN patients. Methods Between 2014 and 2015, a cross-sectional pilot study of 16 female patients who met the Diagnostic and Statistics Manual of Mental Disorders, fifth edition (DSM-5) criteria for AN was conducted at a single tertiary care center. Baseline characteristics including age, weight, food restriction behavior, over-exercise, self-induced vomiting, and laxative abuse were collected in the study population. Electrocardiography, transthoracic echocardiography (TTE), and CMR were performed. Results The mean age was 17 years (range: 13-22 years). There were no conduction abnormalities as the average PR interval was 152 ms (range: 130-190 ms) and QTc was 413 ms (range: 360-450 ms). Using TTE, the left ventricular ejection fraction (LVEF) was 54 ± 4% with a lower LV mass/body surface area (BSA) of 56 ± 7g/m 2  in AN patients as compared to controls. Using CMR, both the mean LVEF of 52 ± 9% and LV mass/BSA of 45 ± 4g/m 2  were lower in AN patients as compared to controls. Using CMR, both right ventricular ejection fraction (RVEF) of 50 ± 10% and a right ventricular (RV) mass/BSA of 18 ± 3g/m 2  were smaller in AN patients as compared to controls. There was no evidence of late gadolinium enhancement (LGE) in the study population. Conclusions Young patients with AN have lower cardiac mass and volumes with no evidence of myocardial fibrosis.
Competing Interests: The authors have declared that no competing interests exist.
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فهرسة مساهمة: Keywords: anorexia nervosa; cardiac magnetic resonance imaging; cardiovascular remodelling; transthoracic echocardiography
تواريخ الأحداث: Date Created: 20190525 Latest Revision: 20201001
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC6510561
DOI: 10.7759/cureus.4229
PMID: 31123651
قاعدة البيانات: MEDLINE
الوصف
تدمد:2168-8184
DOI:10.7759/cureus.4229