دورية أكاديمية

Unravelling nuclear size control.

التفاصيل البيبلوغرافية
العنوان: Unravelling nuclear size control.
المؤلفون: Cantwell H; Cell Cycle Laboratory, The Francis Crick Institute, London, NW1 1AT, UK. helena.cantwell@berkeley.edu.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA. helena.cantwell@berkeley.edu., Nurse P; Cell Cycle Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.; Laboratory of Yeast Genetics and Cell Biology, Rockefeller University, New York, NY, 10065, USA.
المصدر: Current genetics [Curr Genet] 2019 Dec; Vol. 65 (6), pp. 1281-1285. Date of Electronic Publication: 2019 May 31.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Springer International Country of Publication: United States NLM ID: 8004904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0983 (Electronic) Linking ISSN: 01728083 NLM ISO Abbreviation: Curr Genet Subsets: MEDLINE
أسماء مطبوعة: Publication: New York Ny : Springer International
Original Publication: [New York] Springer International.
مواضيع طبية MeSH: Cell Nucleus/*genetics , Cell Nucleus Size/*genetics, Active Transport, Cell Nucleus ; Animals ; Cell Nucleus/metabolism ; Cell Nucleus/physiology ; Cell Nucleus Size/physiology ; Cytoplasm/genetics ; Cytoplasm/metabolism ; Humans ; Nuclear Envelope/genetics ; Nuclear Envelope/metabolism ; Nuclear Matrix/genetics ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Schizosaccharomyces/genetics
مستخلص: Correlation between nuclear and cell size, the nucleocytoplasmic ratio, is a cellular phenomenon that has been reported throughout eukaryotes for more than a century but the mechanisms that achieve it are not well understood. Here, we review work that has shed light on the cellular processes involved in nuclear size control. These studies have implicated nucleocytoplasmic transport, LINC complexes, RNA processing, regulation of nuclear envelope expansion and partitioning of importin α in nuclear size control, moving us closer to a mechanistic understanding of this phenomenon.
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معلومات مُعتمدة: United Kingdom WT_ Wellcome Trust; 093917 United Kingdom WT_ Wellcome Trust; FC01121 The Francis Crick Institute
فهرسة مساهمة: Keywords: Fission yeast; Intracellular scaling; Nuclear envelope; Nucleocytoplasmic transport; Nucleus; Organelles; Size control
المشرفين على المادة: 0 (RNA, Long Noncoding)
0 (RNA, Messenger)
تواريخ الأحداث: Date Created: 20190601 Date Completed: 20200413 Latest Revision: 20211006
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC6820586
DOI: 10.1007/s00294-019-00999-3
PMID: 31147736
قاعدة البيانات: MEDLINE
الوصف
تدمد:1432-0983
DOI:10.1007/s00294-019-00999-3