دورية أكاديمية
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Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity.

التفاصيل البيبلوغرافية
العنوان: Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity.
المؤلفون: Kazak L; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada. lawrence.kazak@mcgill.ca.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada. lawrence.kazak@mcgill.ca., Rahbani JF; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada., Samborska B; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada., Lu GZ; Dana-Farber Cancer Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Jedrychowski MP; Dana-Farber Cancer Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Lajoie M; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada., Zhang S; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Ramsay L; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada., Dou FY; Dana-Farber Cancer Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Tenen D; Division of Endocrinology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Chouchani ET; Dana-Farber Cancer Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Dzeja P; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA., Watson IR; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada., Tsai L; Division of Endocrinology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Rosen ED; Division of Endocrinology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Spiegelman BM; Dana-Farber Cancer Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA. bruce_spiegelman@dfci.harvard.edu.
المصدر: Nature metabolism [Nat Metab] 2019; Vol. 1 (3), pp. 360-370. Date of Electronic Publication: 2019 Feb 25.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab
أسماء مطبوعة: Original Publication: Berlin : Springer Nature, [2019]-
مواضيع طبية MeSH: Diet, High-Fat* , Thermogenesis*, Adipocytes/*metabolism , Creatine/*metabolism , Obesity/*etiology, Adipose Tissue, Brown/metabolism ; Animals ; Biological Transport ; Energy Metabolism ; Kininogens/metabolism ; Membrane Transport Proteins/genetics ; Membrane Transport Proteins/metabolism ; Mice ; Mice, Knockout ; Obesity/metabolism ; Subcutaneous Fat/metabolism
مستخلص: Competing Interests: Competing interests. The authors declare no competing interests
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معلومات مُعتمدة: UL1 TR002541 United States TR NCATS NIH HHS; R01 EY017690 United States EY NEI NIH HHS; U24 DK100469 United States DK NIDDK NIH HHS; K99 DK114528 United States DK NIDDK NIH HHS; R01 DK031405 United States DK NIDDK NIH HHS; R01 HL085744 United States HL NHLBI NIH HHS; R01 DK087092 United States DK NIDDK NIH HHS; R01 DK102173 United States DK NIDDK NIH HHS; P30 DK046200 United States DK NIDDK NIH HHS; PJT-159529 Canada CIHR; R37 DK031405 United States DK NIDDK NIH HHS; P30 DK057521 United States DK NIDDK NIH HHS
المشرفين على المادة: 0 (Kininogens)
0 (Membrane Transport Proteins)
0 (creatine transporter)
MU72812GK0 (Creatine)
تواريخ الأحداث: Date Created: 20190605 Date Completed: 20210119 Latest Revision: 20220416
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC6544051
DOI: 10.1038/s42255-019-0035-x
PMID: 31161155
قاعدة البيانات: MEDLINE
الوصف
تدمد:2522-5812
DOI:10.1038/s42255-019-0035-x