دورية أكاديمية
Overlapping transcription units in the transient receptor potential locus of Drosophila melanogaster.
| العنوان: | Overlapping transcription units in the transient receptor potential locus of Drosophila melanogaster. |
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| المؤلفون: | Wong F; Department of Ophthalmology, University of Illinois at Chicago 60612., Yuh ZT, Schaefer EL, Roop BC, Ally AH |
| المصدر: | Somatic cell and molecular genetics [Somat Cell Mol Genet] 1987 Nov; Vol. 13 (6), pp. 661-9. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
| اللغة: | English |
| بيانات الدورية: | Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8403568 Publication Model: Print Cited Medium: Print ISSN: 0740-7750 (Print) Linking ISSN: 07407750 NLM ISO Abbreviation: Somat Cell Mol Genet Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 1999- : New York, NY : Kluwer Academic/Plenum Publishers Original Publication: New York : Plenum Press, c1984- |
| مواضيع طبية MeSH: | Chromosome Mapping* , Genes* , Transcription, Genetic*, Drosophila melanogaster/*genetics , RNA, Messenger/*genetics, Amino Acid Sequence ; Animals ; Base Sequence ; DNA/genetics ; Molecular Sequence Data ; Photoreceptor Cells/abnormalities |
| مستخلص: | We report the identification in Drosophila melanogaster of two mRNA transcripts that are derived from the transient receptor potential locus by transcription in opposite directions. The two transcripts overlap; one transcript has, as part of its 5'-untranslated sequence, the reverse complement of 442 bp of the 3' terminus of the transcript derived from the opposite DNA strand. Conceptual translation of the corresponding cDNA sequences predicted for one of the transcripts a polypeptide whose C terminus shares sequence and structural similarity with the cell-wall-binding domain of protein A from Staphylococcus aureus; for the transcript derived from the opposite DNA strand, a polypeptide of 264 amino acids was predicted, which showed no significant sequence homology with any known protein. The two transcripts have different tissue specificities: one is expressed predominantly in the eye and the other is in the body. These findings may have implications in the relationship between the organization of overlapping genes on opposite DNA strands and regulation of gene expression by antisense RNA. |
| معلومات مُعتمدة: | 1 U41 RR-01685-05 United States RR NCRR NIH HHS; KO4 EY-00283 United States EY NEI NIH HHS; R01 EY-06862 United States EY NEI NIH HHS |
| سلسلة جزيئية: | GENBANK M18634; M18635 |
| المشرفين على المادة: | 0 (RNA, Messenger) 9007-49-2 (DNA) |
| تواريخ الأحداث: | Date Created: 19871101 Date Completed: 19871211 Latest Revision: 20191022 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1007/BF01534486 |
| PMID: | 3118483 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 0740-7750 |
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| DOI: | 10.1007/BF01534486 |