دورية أكاديمية
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Plinia cauliflora (Mart.) Kausel: toxicological assays, biological activities, and elemental analysis of organic compounds.

التفاصيل البيبلوغرافية
العنوان: Plinia cauliflora (Mart.) Kausel: toxicological assays, biological activities, and elemental analysis of organic compounds.
المؤلفون: Mendonça de Assis P; NUPICS, Faculdade de Farmácia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil., Cypriano Dutra R; Laboratório de Autoimunidade e Imunofarmacologia, Departamento de Ciências da Saúde, Universidade Federal de Santa Catarina, Araranguá, Santa Catarina, Brazil., Amarante CBD; Museu Paraense Emílio Goeldi, Belém, Pará, Brazil., Afonso Miranda Chaves MDG; NUPITE, Faculdade de Odontologia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil., Moreira CPS; Serviço de Desenvolvimento Tecnológico Farmacêutico, Diretoria de Pesquisa e Desenvolvimento, Fundação Ezequiel Dias, Belo Horizonte, Minas Gerais, Brazil., Brandão MAF; NUPICS, Faculdade de Farmácia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil., Raposo NRB; NUPICS, Faculdade de Farmácia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
المصدر: Natural product research [Nat Prod Res] 2021 May; Vol. 35 (10), pp. 1727-1731. Date of Electronic Publication: 2019 Jun 26.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Milton Park, UK : Taylor & Francis Health Sciences, c2003-
مواضيع طبية MeSH: Biological Assay* , Elements* , Toxicity Tests*, Myrtaceae/*chemistry , Organic Chemicals/*analysis, Animals ; Antifungal Agents/pharmacology ; Antioxidants/pharmacology ; Brazil ; Candida/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Humans ; Mice ; Microbial Sensitivity Tests ; Plant Extracts/pharmacology
مستخلص: Jaboticaba, Plinia cauliflora (Mart.) Kausel, is a Brazilian berry traditionally used in folk medicine as treatment for some health conditions. Phenolic compounds such as flavonoids and anthocyanins have previously been detected in the fruit. This current study aimed to evaluate the toxicological effects of jaboticaba peel extract (JPE) on Artemia salina , L929, and MDA-MB-231 cell lines. Besides, JPE antioxidant, acetylcholinesterase, and antifungal activities, and elemental analysis CHNS were also tested. JPE had moderate toxicity (LD 50 = 360.92 μg mL -1 ) on A. salina , non-toxic effect on L929 cell line, and decreased the viability of cancer cell line MDA at 1,000 µg mL -1 and 500 µg mL -1 concentrations. The antioxidant activity toward 2,2-diphenyl-1-picrylhydrazyl (DPPH) performed IC 50 = 37.45 ± 0.17 µg mL -1 , whereas 45.7% of acetylcholinesterase activity was inhibited. By its elemental composition, JPE is an alternative food supplement and dermocosmetic component. Antifungal potential toward Candida strains was not observed.
فهرسة مساهمة: Keywords: Jaboticaba; acetylcholinesterase activity; antioxidant capacity; antiproliferative; cell viability; elemental analysis
المشرفين على المادة: 0 (Antifungal Agents)
0 (Antioxidants)
0 (Elements)
0 (Organic Chemicals)
0 (Plant Extracts)
تواريخ الأحداث: Date Created: 20190628 Date Completed: 20210604 Latest Revision: 20210604
رمز التحديث: 20240628
DOI: 10.1080/14786419.2019.1633642
PMID: 31242771
قاعدة البيانات: MEDLINE
الوصف
تدمد:1478-6427
DOI:10.1080/14786419.2019.1633642