دورية أكاديمية
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Lithium bioaccumulation in Lentinus crinitus mycelial biomass as a potential functional food.

التفاصيل البيبلوغرافية
العنوان: Lithium bioaccumulation in Lentinus crinitus mycelial biomass as a potential functional food.
المؤلفون: Faria MGI; Universidade Paranaense, Laboratório de Biologia Molecular, Programa de Pós-graduação Em Biotecnologia Aplicada à Agricultura, Umuarama, PR, Brazil. Electronic address: maria.iecher@edu.unipar.br., Avelino KV; Universidade Paranaense, Laboratório de Biologia Molecular, Programa de Pós-graduação Em Biotecnologia Aplicada à Agricultura, Umuarama, PR, Brazil., do Valle JS; Universidade Paranaense, Laboratório de Biologia Molecular, Programa de Pós-graduação Em Biotecnologia Aplicada à Agricultura, Umuarama, PR, Brazil., da Silva GJ; Universidade Paranaense, Laboratório de Biologia Molecular, Programa de Pós-graduação Em Biotecnologia Aplicada à Agricultura, Umuarama, PR, Brazil., Gonçalves AC Jr; Universidade Estadual Do Oeste Do Paraná, Laboratório de Química Ambiental, Centro de Ciências Agrárias, Marechal Cândido Rondon, PR, Brazil., Dragunski DC; Universidade Estadual Do Oeste Do Paraná, Centro de Engenharia e Ciências Exatas, Toledo, PR, Brazil., Colauto NB; Universidade Paranaense, Laboratório de Biologia Molecular, Programa de Pós-graduação Em Biotecnologia Aplicada à Agricultura, Umuarama, PR, Brazil., Linde GA; Universidade Paranaense, Laboratório de Biologia Molecular, Programa de Pós-graduação Em Biotecnologia Aplicada à Agricultura, Umuarama, PR, Brazil.
المصدر: Chemosphere [Chemosphere] 2019 Nov; Vol. 235, pp. 538-542. Date of Electronic Publication: 2019 Jun 28.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 0320657 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1298 (Electronic) Linking ISSN: 00456535 NLM ISO Abbreviation: Chemosphere Subsets: MEDLINE
أسماء مطبوعة: Publication: Oxford : Elsevier Science Ltd
Original Publication: Oxford, New York, : Pergamon Press.
مواضيع طبية MeSH: Functional Food*, Lentinula/*metabolism , Lithium/*metabolism, Basidiomycota ; Biomass ; Culture Media ; Mycelium/growth & development ; Radioisotopes
مستخلص: Lentinus crinitus is an important basidiomycete consumed by ethnic groups from the Amazon, commonly found in decomposing trees with high lignolytic and antioxidant activities. Lithium is a mood stabilizer, antiepileptic, antipsychotic, and antidepressant used in clinical practice. This study aimed to evaluate L. crinitus mycelial biomass bioaccumulated with lithium in liquid cultivation medium. The malt extract medium was added from zero to 100 mg L -1 lithium from two lithium sources (Li 2 CO 3 and LiCl). The maximum mycelial biomass production was 7218.89 mg L -1 in the culture medium added with 5 mg L -1 lithium from LiCl. The highest lithium concentration in the mycelial biomass was of 574.72 μg g -1 produced in the culture medium with 25 mg L -1 lithium from Li 2 CO 3 . Pearson's correlation showed that Li 2 CO 3 reduces the mycelial biomass and increases lithium bioaccumulation. The maximum translocated lithium from cultivation medium to mycelial biomass was up to 19 or 28% with LiCl or Li 2 CO 3 , respectively. Therefore, although Li 2 CO 3 presents greater inhibition on the mycelial biomass production, it promoted greater lithium bioaccumulation in L. crinitus mycelial biomass and resulted in greater yield of lithium translocation. The equivalent daily dose of lithium for psychiatric treatment, without bioavailability studies, could be reached with 97.4 g lithium-enriched mycelial biomass and, based in the literature, for reduction of violence and criminality rates the amount could be reached with 0.24-0.58 mg. Thus, the development of lithium-enriched mycelial biomass could be an alternative functional food.
(Copyright © 2019 Elsevier Ltd. All rights reserved.)
فهرسة مساهمة: Keywords: Basidiomycete; Bipolar depression; Lithium salts; Mania; Mycelial bioaccumulation; Submerged cultivation
المشرفين على المادة: 0 (Culture Media)
0 (Lithium-4)
0 (Radioisotopes)
9FN79X2M3F (Lithium)
تواريخ الأحداث: Date Created: 20190706 Date Completed: 20191114 Latest Revision: 20191114
رمز التحديث: 20240628
DOI: 10.1016/j.chemosphere.2019.06.218
PMID: 31276867
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-1298
DOI:10.1016/j.chemosphere.2019.06.218