دورية أكاديمية
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Production of low molecular weight chitosan by acid and oxidative pathways: Effect on physicochemical properties.

التفاصيل البيبلوغرافية
العنوان: Production of low molecular weight chitosan by acid and oxidative pathways: Effect on physicochemical properties.
المؤلفون: de Farias BS; School of Chemistry and Food, Federal University of Rio Grande (FURG), km 8 Itália Avenue, 96203-900 Rio Grande, RS, Brazil., Grundmann DDR; School of Chemistry and Food, Federal University of Rio Grande (FURG), km 8 Itália Avenue, 96203-900 Rio Grande, RS, Brazil., Rizzi FZ; School of Chemistry and Food, Federal University of Rio Grande (FURG), km 8 Itália Avenue, 96203-900 Rio Grande, RS, Brazil., Martins NSS; School of Chemistry and Food, Federal University of Rio Grande (FURG), km 8 Itália Avenue, 96203-900 Rio Grande, RS, Brazil., Sant'Anna Cadaval Junior TR; School of Chemistry and Food, Federal University of Rio Grande (FURG), km 8 Itália Avenue, 96203-900 Rio Grande, RS, Brazil., de Almeida Pinto LA; School of Chemistry and Food, Federal University of Rio Grande (FURG), km 8 Itália Avenue, 96203-900 Rio Grande, RS, Brazil. Electronic address: dqmpinto@furg.br.
المصدر: Food research international (Ottawa, Ont.) [Food Res Int] 2019 Sep; Vol. 123, pp. 88-94. Date of Electronic Publication: 2019 Apr 23.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science Country of Publication: Canada NLM ID: 9210143 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7145 (Electronic) Linking ISSN: 09639969 NLM ISO Abbreviation: Food Res Int Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Ottawa, Ontario, Canada : Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science, c1992-
مواضيع طبية MeSH: Chemical Phenomena* , Molecular Weight* , Oxidation-Reduction*, Chitosan/*chemistry, Calorimetry, Differential Scanning ; Hydrogen Peroxide/chemistry ; Magnetic Resonance Spectroscopy ; Polymers/chemistry ; Solubility ; Water/chemistry ; X-Ray Diffraction
مستخلص: Chitosan-based biomaterials with a low molecular weight (LMW) have been drawn attention due to the promising applications in the pharmaceutical and food fields. For this reason, the aim of this work was to study the effect of two distinct depolymerization pathways on the chitosan physicochemical properties. Chitosan was submitted to depolymerization reaction to obtain chitosan with low molecular weight (LMW), using the oxidative pathway (H 2 O 2 ) and the acid pathway (HCl). The molecular weight reduction was investigated by kinetic study and chain scission mechanism. Chitosan characterization was performed according to its viscosimetric average molecular weight and deacetylation degree, respectively, through the viscosimetric method and proton nuclear magnetic resonance spectroscopy ( 1 H NMR). The structural integrity was evaluated by Fourier transform infrared (FTIR) and energy dispersive spectroscopy (EDS). The crystalline and thermal properties were investigated, respectively, by X-ray diffraction (XRD) spectroscopy and thermogravimetric (TGA)/ differential thermal (DTA)/ differential scanning calorimetry (DSC) analysis. The water-chitosan interaction study was used to estimate the chitosan solubility. The results pointed out that both pathways resulted in chitosan with low molecular weight (<50 kDa). Moreover, the structural integrity of chitosan polymeric chains was preserved after depolymerization by oxidative pathway, while the acid pathway modified the polymer chain arrangement. Therefore, the chemical pathways resulted in two distinct low molecular weight chitosans, which allows different applications in food science.
(Copyright © 2019 Elsevier Ltd. All rights reserved.)
فهرسة مساهمة: Keywords: Amorphous; Chain scission; Conformational state; Depolymerization; Double exponential function; Glycosidic bond; Hydrogen bond; Molecular weight
المشرفين على المادة: 0 (Polymers)
059QF0KO0R (Water)
9012-76-4 (Chitosan)
BBX060AN9V (Hydrogen Peroxide)
تواريخ الأحداث: Date Created: 20190710 Date Completed: 20201013 Latest Revision: 20201013
رمز التحديث: 20231215
DOI: 10.1016/j.foodres.2019.04.051
PMID: 31285033
قاعدة البيانات: MEDLINE
الوصف
تدمد:1873-7145
DOI:10.1016/j.foodres.2019.04.051