دورية أكاديمية
Nanocarbons for Biology and Medicine: Sensing, Imaging, and Drug Delivery.
| العنوان: | Nanocarbons for Biology and Medicine: Sensing, Imaging, and Drug Delivery. |
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| المؤلفون: | Panwar N; School of Electrical and Electronic Engineering , Nanyang Technological University , Singapore 639798 , Singapore., Soehartono AM; School of Electrical and Electronic Engineering , Nanyang Technological University , Singapore 639798 , Singapore., Chan KK; School of Electrical and Electronic Engineering , Nanyang Technological University , Singapore 639798 , Singapore., Zeng S; School of Electrical and Electronic Engineering , Nanyang Technological University , Singapore 639798 , Singapore.; CINTRA CNRS/NTU/THALES, UMI 3288 , Research Techno Plaza, 50 Nanyang Drive, Border X Block , Singapore 637553 , Singapore., Xu G; Key Laboratory of Optoelectronics Devices and Systems of Ministry of Education/Guangdong Province, College of Optoelectronic Engineering , Shenzhen University , Shenzhen 518060 , P. R. China., Qu J; Key Laboratory of Optoelectronics Devices and Systems of Ministry of Education/Guangdong Province, College of Optoelectronic Engineering , Shenzhen University , Shenzhen 518060 , P. R. China., Coquet P; CINTRA CNRS/NTU/THALES, UMI 3288 , Research Techno Plaza, 50 Nanyang Drive, Border X Block , Singapore 637553 , Singapore.; Institut d'Electronique, de Microélectronique et de Nanotechnologie (IEMN) , CNRS UMR 8520-Université de Lille , 59650 Villeneuve d'Ascq , France., Yong KT; School of Electrical and Electronic Engineering , Nanyang Technological University , Singapore 639798 , Singapore., Chen X; Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering , National Institutes of Health , Bethesda , Maryland 20892 , United States. |
| المصدر: | Chemical reviews [Chem Rev] 2019 Aug 28; Vol. 119 (16), pp. 9559-9656. Date of Electronic Publication: 2019 Jul 09. |
| نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985134R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6890 (Electronic) Linking ISSN: 00092665 NLM ISO Abbreviation: Chem Rev Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Washington, DC : American Chemical Society Original Publication: Easton, Pa. [etc.] American Chemical Society. |
| مواضيع طبية MeSH: | Drug Delivery Systems/*methods , Nanostructures/*administration & dosage , Nanostructures/*chemistry , Nanotubes, Carbon/*chemistry, Animals ; Biosensing Techniques/methods ; Fullerenes/administration & dosage ; Fullerenes/chemistry ; Graphite/administration & dosage ; Graphite/chemistry ; Humans |
| مستخلص: | Nanocarbons with different dimensions (e.g., 0D fullerenes and carbon nanodots, 1D carbon nanotubes and graphene nanoribbons, 2D graphene and graphene oxides, and 3D nanodiamonds) have attracted enormous interest for applications ranging from electronics, optoelectronics, and photovoltaics to sensing, bioimaging, and therapeutics due to their unique physical and chemical properties. Among them, nanocarbon-based theranostics (i.e., therapeutics and diagnostics) is one of the most intensively studied applications, as these nanocarbon materials serve as excellent biosensors, versatile drug/gene carriers for specific targeting in vivo, effective photothermal nanoagents for cancer therapy, and promising fluorescent nanolabels for cell and tissue imaging. This review provides a systematic overview of the latest theranostic applications of nanocarbon materials with a comprehensive comparison of the characteristics of different nanocarbon materials and their influences on theranostic applications. We first introduce the different carbon allotropes that can be used for theranostic applications with their respective preparation and surface functionalization approaches as well as their physical and chemical properties. Theranostic applications are described separately for both in vitro and in vivo systems by highlighting the protocols and the studied biosystems, followed by the toxicity and biodegradability implications. Finally, this review outlines the design considerations for nanocarbon materials as the key unifying themes that will serve as a foundational first principle for researchers to study, investigate, and generate effective, biocompatible, and nontoxic nanocarbon materials-based models for cancer theranostics applications. Finally, we summarize the review with an outlook on the challenges and novel theranostic protocols using nanocarbon materials for hard-to-treat cancers and other diseases. This review intends to present a comprehensive guideline for researchers in nanotechnology and biomedicine on the selection strategy of nanocarbon materials according to their specific requirements. |
| المشرفين على المادة: | 0 (Fullerenes) 0 (Nanotubes, Carbon) 0 (graphene oxide) 7782-42-5 (Graphite) |
| تواريخ الأحداث: | Date Created: 20190710 Date Completed: 20200717 Latest Revision: 20200717 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1021/acs.chemrev.9b00099 |
| PMID: | 31287663 |
| قاعدة البيانات: | MEDLINE |
Find this issue from the American Chemical Society | تدمد: | 1520-6890 |
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| DOI: | 10.1021/acs.chemrev.9b00099 |