دورية أكاديمية
"We were afraid of the lion that has roared next to us"; community response to reactive focal mass drug administration for malaria in Eswatini (formerly Swaziland).
| العنوان: | "We were afraid of the lion that has roared next to us"; community response to reactive focal mass drug administration for malaria in Eswatini (formerly Swaziland). |
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| المؤلفون: | Baltzell KA; Dept of Family Health Care Nursing, UCSF, San Francisco, CA, USA. Kimberly.Baltzell@ucsf.edu.; Institute for Global Health Sciences, UCSF, San Francisco, CA, USA. Kimberly.Baltzell@ucsf.edu., Maglior A; Institute for Global Health Sciences, UCSF, San Francisco, CA, USA., Bangu K; National Malaria Programme, Eswatini Ministry of Health, Manzini, Swaziland., Mngadi N; Clinton Health Access Initiative, Eswatini Office, Mbabane, Swaziland., Prach LM; Malaria Elimination Initiative, Global Health Group, UCSF, San Francisco, CA, USA., Whittemore B; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Ntshalintshali N; Clinton Health Access Initiative, Eswatini Office, Mbabane, Swaziland., Saini M; Clinton Health Access Initiative, Eswatini Office, Mbabane, Swaziland., Dlamini N; National Malaria Programme, Eswatini Ministry of Health, Manzini, Swaziland., Kunene S; National Malaria Programme, Eswatini Ministry of Health, Manzini, Swaziland., Hsiang MS; Malaria Elimination Initiative, Global Health Group, UCSF, San Francisco, CA, USA.; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Department of Pediatrics, UCSF, San Francisco, CA, USA. |
| المصدر: | Malaria journal [Malar J] 2019 Jul 15; Vol. 18 (1), pp. 238. Date of Electronic Publication: 2019 Jul 15. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BioMed Central, [2002- |
| مواضيع طبية MeSH: | Antimalarials/*therapeutic use , Asymptomatic Infections/*psychology , Malaria/*prevention & control , Mass Drug Administration/*psychology, Eswatini ; Health Knowledge, Attitudes, Practice ; Malaria/psychology |
| مستخلص: | Background: Reactive focal mass drug administration (rfMDA), or presumptive treatment without malaria testing of household members and neighbours of a passively identified malaria case, is currently being explored as a possible malaria elimination strategy in low transmission settings. One of the primary factors determining the effectiveness of rfMDA on reducing or interrupting transmission is achieving high coverage of the target population with drug administration. This study aims to explore the acceptability of rfMDA and identify facilitators and barriers to its potential implementation, as well as the community's general knowledge, attitudes and beliefs with regard to malaria elimination. Methods: A qualitative study was performed using focus group discussions (FGDs) among villagers that received rfMDA through the National Malaria Control Programme in the low transmission setting of Eswatini as part of a 2-year clinical trial. FGDs were audio-recorded, transcribed and translated into English. All transcripts were managed in Dedoose and underwent qualitative content analysis. Results: The majority of participants perceived their community to be at high risk of malaria. Witnessing others in their community suffer from malaria, proximity to Mozambique, various ecological factors, and the presence of mosquitoes contributed to this perception. The greatest motivator of participation in rfMDA was witnessing someone else suffer from malaria, since most participants had not personally experienced malaria themselves. Participants valued the education on rfMDA and on malaria in general, particularly when communicated by nurses and other health workers from the Ministry of Health. Participants were overwhelmingly motivated to participate in rfMDA in order to obtain protection from malaria. Most participants did not understand the concept of sub-clinical infection and, therefore, did not perceive the anti-malarial medication given in rfMDA to be a treatment medication. Conclusions: Perceived risk for malaria was a major driver of acceptability; therefore, future intervention campaigns could aim to better quantify risk to inform interventions and encourage uptake. There were misunderstandings about the asymptomatic reservoir of parasites in humans. Given that this phenomenon is the rationale for rfMDA, this misunderstanding could threaten the uptake of the intervention if it persists in the community. Using local authorities to deliver messaging, additional education on this concept with re-inforcement that risk of malaria is ongoing, even in the absence of frequent cases, may help to maximize and maintain acceptability. |
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| معلومات مُعتمدة: | K23 AI101012 United States AI NIAID NIH HHS; A122394 Bill and Melinda Gates Foundation; 5300375400 Horchow Family Fund Scholarship |
| فهرسة مساهمة: | Keywords: Community acceptance; Eswatini; Malaria elimination; Malaria mass drug administration |
| المشرفين على المادة: | 0 (Antimalarials) |
| تواريخ الأحداث: | Date Created: 20190717 Date Completed: 20191111 Latest Revision: 20200225 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC6631448 |
| DOI: | 10.1186/s12936-019-2877-9 |
| PMID: | 31307494 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1475-2875 |
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| DOI: | 10.1186/s12936-019-2877-9 |