دورية أكاديمية
أعرض في EDS

Early continuous renal replacement therapy during infant extracorporeal life support is associated with decreased lung opacification.

التفاصيل البيبلوغرافية
العنوان: Early continuous renal replacement therapy during infant extracorporeal life support is associated with decreased lung opacification.
المؤلفون: Murphy HJ; Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, USA. murphyh@musc.edu.; Division of Neonatology, Medical University of South Carolina, 165 Ashley Avenue, MSC 917, Charleston, South Carolina, 29425, USA. murphyh@musc.edu., Eklund MJ; Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, USA.; Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, South Carolina, USA., Hill J; Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, USA.; Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, South Carolina, USA., Morella K; Department of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina, USA., Cahill JB; Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, USA., Kiger JR; Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Twombley KE; Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, USA., Annibale DJ; Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, USA. annibald@musc.edu.; Division of Neonatology, Medical University of South Carolina, 165 Ashley Avenue, MSC 917, Charleston, South Carolina, 29425, USA. annibald@musc.edu.
المصدر: Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs [J Artif Organs] 2019 Dec; Vol. 22 (4), pp. 286-293. Date of Electronic Publication: 2019 Jul 25.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Verlag Country of Publication: Japan NLM ID: 9815648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-0904 (Electronic) Linking ISSN: 14347229 NLM ISO Abbreviation: J Artif Organs Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Tokyo : Springer Verlag, c1998-
مواضيع طبية MeSH: Computer Simulation* , Models, Theoretical*, Continuous Renal Replacement Therapy/*methods , Extracorporeal Membrane Oxygenation/*methods , Heart Failure/*physiopathology , Hemodynamics/*physiology , Renal Insufficiency/*therapy, Heart Failure/complications ; Heart Failure/therapy ; Humans ; Infant ; Lung/diagnostic imaging ; Renal Insufficiency/complications ; Renal Insufficiency/physiopathology ; Reproducibility of Results ; Retrospective Studies ; Time Factors
مستخلص: Lung opacification on chest radiography (CXR) is common during extracorporeal life support (ECLS), often resulting from pulmonary edema or inflammation. Concurrent use of continuous renal replacement therapy (CRRT) during ECLS is associated with improved fluid balance and cytokine filtration; through modification of these pathologic states, CRRT may modulate lung opacification observed on CXRs. We hypothesize that early CRRT use during infant ECLS decreases lung opacification on CXR. We conducted a retrospective cohort study comparing CXRs from infants receiving ECLS and early CRRT (n = 7) to matched infants who received ECLS alone (n = 7). The CXR obtained prior to ECLS, all CXRs obtained within the first 72 h of ECLS, and daily CXRs for the remainder of the ECLS course were analyzed. The outcome measure was the degree of opacification, determined by independent assessment of two, blinded pediatric radiologists using a modified Edwards et al.'s lung opacification scoring system (from Score 0: no opacification to Score 5: complete opacification). 220 CXRs were assessed (cases: 93, controls: 127). Inter-rater reliability was established (Cohen's weighted к = 0.74; p < 0.0001, good agreement). At baseline, the mean opacification score difference between cases and controls was 1 point (cases: 1.8, controls 2.8; p = 0.049). Using mixed modeling analysis for repeated measures accounting for differences at baseline, the average overall opacification score was 1.2 points lower in cases than controls (cases: 2.1, controls: 3.3; p < 0.0001). The overall distribution of scores was lower in cases than controls. Early CRRT utilization during infant ECLS was associated with decreased lung opacification on CXR.
التعليقات: Comment in: J Artif Organs. 2021 Jun;24(2):305-306. (PMID: 32671508)
References: ASAIO J. 1999 Jul-Aug;45(4):250-63. (PMID: 10445729)
Intensive Care Med. 2008 Dec;34(12):2241-7. (PMID: 18629472)
Crit Care Med. 2004 Aug;32(8):1771-6. (PMID: 15286557)
Intensive Care Med. 2003 Nov;29(11):1989-95. (PMID: 12955174)
J Artif Organs. 2018 Mar;21(1):76-85. (PMID: 29086091)
Pediatrics. 2001 Jun;107(6):1309-12. (PMID: 11389248)
Radiology. 1996 Mar;198(3):693-8. (PMID: 8628856)
Crit Care. 2009;13(2):R48. (PMID: 19344497)
J Ren Nutr. 2018 Jan;28(1):64-70. (PMID: 28964639)
Radiology. 1985 Nov;157(2):329-34. (PMID: 3840268)
Clin J Am Soc Nephrol. 2012 Aug;7(8):1328-36. (PMID: 22498496)
Pediatr Crit Care Med. 2017 Dec;18(12):1126-1135. (PMID: 28937504)
Inflammation. 2013 Oct;36(5):1186-93. (PMID: 23700116)
Lab Invest. 2010 Jan;90(1):128-39. (PMID: 19901912)
Pediatr Crit Care Med. 2012 May;13(3):253-8. (PMID: 21760565)
Ren Fail. 1995 Jul;17(4):457-66. (PMID: 7569116)
Pediatr Res. 2012 Sep;72(3):249-55. (PMID: 22669297)
Am J Kidney Dis. 2010 Feb;55(2):316-25. (PMID: 20042260)
J Pediatr Surg. 1991 Sep;26(9):1016-22. (PMID: 1941476)
Crit Care. 2013 Jul 24;17(4):R151. (PMID: 23883698)
Ann Thorac Surg. 2013 Sep;96(3):917-22. (PMID: 23915590)
Pediatr Crit Care Med. 2011 Jan;12(1):e1-6. (PMID: 20351617)
Crit Care Med. 2012 Sep;40(9):2694-9. (PMID: 22743776)
ASAIO J. 2017 Jul/Aug;63(4):456-463. (PMID: 28557863)
Radiology. 1986 Nov;161(2):347-50. (PMID: 3763898)
فهرسة مساهمة: Keywords: Continuous renal replacement therapy; Extracorporeal life support; Extracorporeal membrane oxygenation; Lung opacification; Renal support therapy
تواريخ الأحداث: Date Created: 20190726 Date Completed: 20200224 Latest Revision: 20210802
رمز التحديث: 20240628
DOI: 10.1007/s10047-019-01119-1
PMID: 31342287
قاعدة البيانات: MEDLINE
الوصف
تدمد:1619-0904
DOI:10.1007/s10047-019-01119-1