دورية أكاديمية
أعرض في EDS

Favourable outcome after late reorientation of an upside-down Descemet Membrane Endothelial Keratoplasty (DMEK) graft: a case report.

التفاصيل البيبلوغرافية
العنوان: Favourable outcome after late reorientation of an upside-down Descemet Membrane Endothelial Keratoplasty (DMEK) graft: a case report.
المؤلفون: Mariacher S; Knappschaft Eye Clinic, Knappschaft Hospital Saar GmbH, An der Klinik 10, 66280, Sulzbach, Germany. siegfried.mariacher@gmail.com., Mariacher M; Knappschaft Eye Clinic, Knappschaft Hospital Saar GmbH, An der Klinik 10, 66280, Sulzbach, Germany., Boden KT; Knappschaft Eye Clinic, Knappschaft Hospital Saar GmbH, An der Klinik 10, 66280, Sulzbach, Germany., Szurman P; Knappschaft Eye Clinic, Knappschaft Hospital Saar GmbH, An der Klinik 10, 66280, Sulzbach, Germany.; Centre for Ophthalmology, University Eye Hospital Tuebingen, Schleichstr. 12, 72076, Tuebingen, Germany., Januschowski K; Knappschaft Eye Clinic, Knappschaft Hospital Saar GmbH, An der Klinik 10, 66280, Sulzbach, Germany.; Centre for Ophthalmology, University Eye Hospital Tuebingen, Schleichstr. 12, 72076, Tuebingen, Germany.
المصدر: BMC ophthalmology [BMC Ophthalmol] 2019 Jul 29; Vol. 19 (1), pp. 163. Date of Electronic Publication: 2019 Jul 29.
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100967802 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2415 (Electronic) Linking ISSN: 14712415 NLM ISO Abbreviation: BMC Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Cornea/*pathology , Descemet Stripping Endothelial Keratoplasty/*methods , Fuchs' Endothelial Dystrophy/*surgery , Graft Rejection/*prevention & control , Tissue and Organ Harvesting/*methods , Visual Acuity/*physiology, Aged ; Cornea/surgery ; Female ; Follow-Up Studies ; Fuchs' Endothelial Dystrophy/diagnosis ; Graft Survival ; Humans ; Time Factors ; Tomography, Optical Coherence
مستخلص: Background: Clinical outcome after successful reorientation of an upside-down implanted DMEK (Descemet Membrane Endothelial Keratoplasty) graft 4 weeks after initial transplantation.
Case Presentation: A 71-year-old woman presented with Fuchs' endothelial corneal dystrophy for DMEK. After initial DMEK the donor graft was fully attached and well centred during intracameral gas filling. When the gas bubble was fully resorbed the graft started to detach. Therefore, two intracameral gas injections were consecutively performed. During the second re-bubbling, an upside-down orientation was observed and so the graft was flipped, centred, re-attached and finally stabilized by an intracameral gas bubble. Three weeks after reorientation slit lamp examinations showed a well centred and attached graft, endothelial cells that started functioning and a patient's visual acuity of 20/40. Visual acuity increased to a 20/32 vision in the observed eye three months later and further improved to 20/20 6 months after reorientation and stayed stable between 20/32 and 20/20 during the remaining 15 months of follow-up, with a clear and well-attached graft.
Conclusion: Reorientation of an upside down DMEK graft was successful even 4 weeks after initial DMEK. Visual recovery and endothelial cell count increase were stepwise noticed during the first 6 months and 15 months after reorientation, respectively. Finally a favourable outcome with 20/32 to 20/20 vision at least 6 months after graft reorientation was achieved. Therefore, restoring full graft function could last several weeks or even months following (late) reorientation of an upside-down DMEK graft.
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فهرسة مساهمة: Keywords: DMEK; Graft failure; Graft reorientation procedure; Inversion; Re-bubbling; Upside-down
تواريخ الأحداث: Date Created: 20190731 Date Completed: 20190813 Latest Revision: 20200225
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC6664698
DOI: 10.1186/s12886-019-1181-3
PMID: 31357966
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2415
DOI:10.1186/s12886-019-1181-3