دورية أكاديمية
أعرض في EDS

Roux-Y Gastric Bypass and Sleeve Gastrectomy directly change gut microbiota composition independent of surgery type.

التفاصيل البيبلوغرافية
العنوان: Roux-Y Gastric Bypass and Sleeve Gastrectomy directly change gut microbiota composition independent of surgery type.
المؤلفون: Paganelli FL; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Luyer M; Department of Surgery, Catharina Hospital Eindhoven, Eindhoven, The Netherlands., Hazelbag CM; Department of Biostatistics and Research Support, Julius Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Uh HW; Department of Biostatistics and Research Support, Julius Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Rogers MRC; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Adriaans D; Department of Surgery, Catharina Hospital Eindhoven, Eindhoven, The Netherlands., Berbers RM; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Hendrickx APA; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Viveen MC; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Groot JA; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Bonten MJM; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Fluit AC; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Willems RJL; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Leavis HL; Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. h.leavis@umcutrecht.nl.
المصدر: Scientific reports [Sci Rep] 2019 Jul 29; Vol. 9 (1), pp. 10979. Date of Electronic Publication: 2019 Jul 29.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : Nature Publishing Group, copyright 2011-
مواضيع طبية MeSH: Gastrectomy*/methods , Gastric Bypass*/methods , Gastrointestinal Microbiome*, Obesity/*diet therapy , Obesity/*surgery, Adult ; Bariatric Surgery ; Female ; Humans ; Male ; Middle Aged ; Obesity/microbiology ; Weight Loss
مستخلص: Bariatric surgery in morbid obesity, either through sleeve gastrectomy (SG) or Roux-Y gastric bypass (RYGB), leads to sustainable weight loss, improvement of metabolic disorders and changes in intestinal microbiota. Yet, the relationship between changes in gut microbiota, weight loss and surgical procedure remains incompletely understood. We determined temporal changes in microbiota composition in 45 obese patients undergoing crash diet followed by SG (n = 22) or RYGB (n = 23). Intestinal microbiota composition was determined before intervention (baseline, S1), 2 weeks after crash diet (S2), and 1 week (S3), 3 months (S4) and 6 months (S5) after surgery. Relative to S1, the microbial diversity index declined at S2 and S3 (p < 0.05), and gradually returned to baseline levels at S5. Rikenellaceae relative abundance increased and Ruminococcaceae and Streptococcaceae abundance decreased at S2 (p < 0.05). At S3, Bifidobacteriaceae abundance decreased, whereas those of Streptococcaceae and Enterobacteriaceae increased (p < 0.05). Increased weight loss between S3-S5 was not associated with major changes in microbiota composition. No significant differences appeared between both surgical procedures. In conclusion, undergoing a crash diet and bariatric surgery were associated with an immediate but temporary decline in microbial diversity, with immediate and permanent changes in microbiota composition, independent of surgery type.
References: Diabetes Metab Res Rev. 2017 Mar;33(3):. (PMID: 27572277)
Nutr Metab (Lond). 2016 Feb 20;13:14. (PMID: 26900391)
Diabetes. 2010 Dec;59(12):3049-57. (PMID: 20876719)
JAMA Surg. 2013 Jun;148(6):563-9. (PMID: 23571517)
Gut. 2011 Sep;60(9):1214-23. (PMID: 21572120)
Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16731-6. (PMID: 18936492)
Diabetes. 2016 Oct;65(10):2990-3001. (PMID: 27431457)
Am J Clin Nutr. 2013 Jul;98(1):16-24. (PMID: 23719559)
Gut. 2019 Jan;68(1):70-82. (PMID: 29899081)
Appl Environ Microbiol. 1997 Jul;63(7):2802-13. (PMID: 9212428)
Front Microbiol. 2016 Feb 23;7:200. (PMID: 26941724)
Cell Metab. 2015 Aug 4;22(2):228-38. (PMID: 26244932)
Eur J Endocrinol. 2018 Jan;178(1):43-56. (PMID: 28916564)
Can J Microbiol. 2016 Aug;62(8):692-703. (PMID: 27314511)
Genome Med. 2016 Jun 15;8(1):67. (PMID: 27306058)
Nat Methods. 2010 May;7(5):335-6. (PMID: 20383131)
BMC Bioinformatics. 2008 Jul 09;9:303. (PMID: 18613966)
ISME J. 2017 Sep;11(9):2047-2058. (PMID: 28548658)
J Clin Gastroenterol. 2010 Sep;44 Suppl 1:S16-8. (PMID: 20535027)
Biomed Res Int. 2015;2015:806248. (PMID: 25710027)
Obes Surg. 2017 Apr;27(4):917-925. (PMID: 27738970)
Microbiome. 2014 Feb 24;2(1):6. (PMID: 24558975)
Trends Endocrinol Metab. 2018 Mar;29(3):140-150. (PMID: 29409713)
Nat Med. 2017 Jul;23(7):859-868. (PMID: 28628112)
Bioinformatics. 2010 Oct 1;26(19):2460-1. (PMID: 20709691)
Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2365-70. (PMID: 19164560)
Bioinformatics. 2011 Nov 1;27(21):2957-63. (PMID: 21903629)
Pharmacogenomics J. 2013 Dec;13(6):514-22. (PMID: 23032991)
Biochim Biophys Acta. 1972 Mar 30;264(1):85-97. (PMID: 4553810)
Cell Host Microbe. 2008 Apr 17;3(4):213-23. (PMID: 18407065)
Microb Ecol Health Dis. 2015 May 29;26:27663. (PMID: 26028277)
Sci Transl Med. 2013 Mar 27;5(178):178ra41. (PMID: 23536013)
Am J Physiol Regul Integr Comp Physiol. 2011 Oct;301(4):R1057-66. (PMID: 21734019)
Obes Surg. 2017 Feb;27(2):295-302. (PMID: 27440168)
Obes Surg. 2014 Sep;24(9):1567-71. (PMID: 24849914)
تواريخ الأحداث: Date Created: 20190731 Date Completed: 20201026 Latest Revision: 20210110
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC6662812
DOI: 10.1038/s41598-019-47332-z
PMID: 31358818
قاعدة البيانات: MEDLINE
الوصف
تدمد:2045-2322
DOI:10.1038/s41598-019-47332-z