دورية أكاديمية
Prevalence of rotavirus and human bocavirus in immunosuppressed individuals after renal transplantation in the Northern Region of Brazil.
| العنوان: | Prevalence of rotavirus and human bocavirus in immunosuppressed individuals after renal transplantation in the Northern Region of Brazil. |
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| المؤلفون: | Castro LRP; Postgraduate Program in Epidemiology and Surveillance in Health, Evandro Chagas Institute, Ananindeua, Pará, Brazil., Calvet FC; Laboratory of Rotavirus, Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil., Sousa KL; Laboratory of Rotavirus, Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil., Silva VP; Laboratory of Rotavirus, Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil., Lobo PS; Laboratory of Rotavirus, Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil., Penha ET Junior; Laboratory of Rotavirus, Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil., Guerra SFS; Laboratory of Rotavirus, Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil., Bezerra DAM; Laboratory of Rotavirus, Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil., Mascarenhas JDP; Laboratory of Rotavirus, Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil., Pinheiro HHC; Center for Tropical Medicine, Federal University of Pará, Belém, Pará, Brazil., Costa IB; Laboratory of Rotavirus, Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil., Resque HR; Laboratory of Rotavirus, Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil., Soares LS; Laboratory of Rotavirus, Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil. |
| المصدر: | Journal of medical virology [J Med Virol] 2019 Dec; Vol. 91 (12), pp. 2125-2133. Date of Electronic Publication: 2019 Aug 29. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York Ny : Wiley-Liss Original Publication: New York, Liss. |
| مواضيع طبية MeSH: | Immunocompromised Host*, Feces/*virology , Human bocavirus/*isolation & purification , Kidney Transplantation/*adverse effects , Rotavirus/*isolation & purification, Adult ; Brazil/epidemiology ; Coinfection/epidemiology ; Coinfection/virology ; Female ; Genotype ; Human bocavirus/genetics ; Humans ; Longitudinal Studies ; Male ; Parvoviridae Infections/epidemiology ; Parvoviridae Infections/virology ; Phylogeny ; Prevalence ; Rotavirus/genetics ; Rotavirus Infections/epidemiology ; Rotavirus Infections/virology ; Sequence Analysis, DNA ; Transplant Recipients/statistics & numerical data |
| مستخلص: | Immunosuppressive therapy causes severe impairment of host defense and diarrhea is a frequent complication in renal transplant recipients. This study aimed to describe the occurrence of Rotavirus A (RVA) and Human Bocavirus (HBoV) in fecal samples of immunosuppressed patients submitted to renal transplantation during posttransplant follow-up. A longitudinal study was carried out involving a 25-patient cohort, selected for kidney transplantation. A total of 126 fecal samples were collected between May 2014 and May 2016. Molecular techniques were used to detect and characterize circulating RVA and HBoV genotypes and statistical analysis were applied to verify the association between epidemiological and clinical characteristics. The prevalence of RVA and HBoV was 24% (6/25) and 40% (10/25), respectively. Among RVA and HBoV positive cases, the majority was female; did not conduct water treatment nor had adequate sewage facilities. The most detected genotypes were RVA G3 (62.5%) and HBoV-3 (95%). Phylogenetic analysis of HBoV strains indicated that studied samples were similar to those found in Asian and American countries. The present study point out the circulation of these viral agents among immunosuppressed individuals and these findings will enable the construction of new knowledge and care perspectives on the cause of diarrhea in this population. (© 2019 Wiley Periodicals, Inc.) |
| فهرسة مساهمة: | Keywords: Human Bocavirus; kidney transplantation; rotavirus |
| تواريخ الأحداث: | Date Created: 20190821 Date Completed: 20200715 Latest Revision: 20200715 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1002/jmv.25569 |
| PMID: | 31429939 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1096-9071 |
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| DOI: | 10.1002/jmv.25569 |