تقرير
Aldosterone-Secreting Adrenocortical Carcinoma Presenting With Cardiac Arrest.
| العنوان: | Aldosterone-Secreting Adrenocortical Carcinoma Presenting With Cardiac Arrest. |
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| المؤلفون: | Zern NK; Division of General Surgery, Department of Surgery, University of Washington, Seattle, Washington., Eaton KD; Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, Washington., Roth MY; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington, Seattle, Washington. |
| المصدر: | Journal of the Endocrine Society [J Endocr Soc] 2019 Jun 12; Vol. 3 (9), pp. 1678-1681. Date of Electronic Publication: 2019 Jun 12 (Print Publication: 2019). |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Endocrine Society Country of Publication: United States NLM ID: 101697997 Publication Model: eCollection Cited Medium: Internet ISSN: 2472-1972 (Electronic) Linking ISSN: 24721972 NLM ISO Abbreviation: J Endocr Soc Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Washington, DC : Endocrine Society, [2017]- |
| مستخلص: | Adrenocortical carcinoma (ACC) is a rare malignancy that usually is detected as a result of symptoms of hormone excess or mass effect. We describe a rare presentation of ACC with primary aldosterone production leading to profound hypokalemia and cardiac arrest. The patient was previously asymptomatic with low-grade, untreated hypertension and no documented electrolyte abnormalities. She had sudden cardiac arrest, and potassium levels were undetectable. After successful resuscitation, imaging showed a 6-cm left adrenal mass highly suspicious for malignancy. Biochemical workup revealed aldosterone excess as well as cortisol excess, despite the absence of Cushingoid symptoms. Histopathological examination after surgical resection demonstrated high-grade ACC. This case illustrates that the workup of cardiac arrest as a result of electrolyte abnormalities should include evaluation for adrenal pathology. |
| References: | Can J Cardiol. 1999 Mar;15(3):347-8. (PMID: 10202199) J Urol. 2003 Jan;169(1):5-11. (PMID: 12478091) Am J Med. 1955 Dec;19(6):966-75. (PMID: 13275491) Endocr Pathol. 2014 Sep;25(3):344-9. (PMID: 24682757) Urol Int. 1995;55(4):232-5. (PMID: 8588274) |
| فهرسة مساهمة: | Keywords: adrenal mass; adrenocortical carcinoma; hyperaldosteronism; hypokalemia |
| تواريخ الأحداث: | Date Created: 20190824 Latest Revision: 20200929 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC6698141 |
| DOI: | 10.1210/js.2019-00092 |
| PMID: | 31440735 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2472-1972 |
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| DOI: | 10.1210/js.2019-00092 |