دورية أكاديمية
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Administration of ginger and/or thyme has ameliorative effects on liver and kidney functions of V-line rabbits: Histological and biochemical studies.

التفاصيل البيبلوغرافية
العنوان: Administration of ginger and/or thyme has ameliorative effects on liver and kidney functions of V-line rabbits: Histological and biochemical studies.
المؤلفون: Abdel-Gabbar M; Biochemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt., Ahmed RR; Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt., Kandeil MA; Biochemistry Department, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, Egypt., Mohamed AEH; Animal Production Research Institute, Agricultural Research Center, Giza, Egypt., Ali SM; Animal Production Research Institute, Agricultural Research Center, Giza, Egypt.
المصدر: Journal of animal physiology and animal nutrition [J Anim Physiol Anim Nutr (Berl)] 2019 Nov; Vol. 103 (6), pp. 1758-1767. Date of Electronic Publication: 2019 Aug 22.
نوع المنشور: Journal Article; Randomized Controlled Trial, Veterinary
اللغة: English
بيانات الدورية: Publisher: Blackwell Science Country of Publication: Germany NLM ID: 101126979 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0396 (Electronic) Linking ISSN: 09312439 NLM ISO Abbreviation: J Anim Physiol Anim Nutr (Berl) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Berlin] : Blackwell Science, c2001-
مواضيع طبية MeSH: Zingiber officinale* , Rabbits* , Thymus Plant*, Kidney/*drug effects , Liver/*drug effects, Animal Feed/analysis ; Animal Nutritional Physiological Phenomena ; Animals ; Antioxidants/metabolism ; Diet/veterinary ; Kidney/anatomy & histology ; Lipid Metabolism/drug effects ; Liver/anatomy & histology ; Male ; Oxidative Stress
مستخلص: This study was conducted to evaluate the effect of Zingiber officinale and Thymus vulgaris aqueous extracts as a natural antioxidant on liver and kidney functions and antioxidant status of growing rabbits. A total of 24 V-line male rabbits, 3 months old, 1.465 ± 0.12 kg average body weight (BW) were used in a complete randomized design. The rabbits were weighed individually and assigned randomly to four groups (6 animals/each). The first group (G1) was taken fresh water and served as control, rabbits of the second group (G2) were taken 100 mg/kg BW in drinking water of the Z. officinale aqueous extract daily. The third group (G3) was taken 50 mg/kg BW in drinking water of the T. vulgaris aqueous extract daily and the fourth group (G4) was taken 100 mg/kg BW of the Z. officinale aqueous extract plus 50 mg/kg BW of the T. vulgaris aqueous extract in drinking water daily. The oral administration of ginger and/or thyme aqueous extracts increased (p < .001) serum protein profile compared with control group. Moreover, results of group 2 showed significant (p < .001) decrease in cholesterol, triglyceride and very low-density lipoprotein cholesterol compared with group 3 and 4. Serum urea, uric acid and creatinine levels were significantly (p < .001) decreased in treated groups compared with control group. Oral administration of ginger and/or thyme aqueous extracts to growing rabbits increased (p < .001) total antioxidant capacity and glutathione content and the activity of superoxide dismutase, catalase and glutathione-S-transferase compared with the control group. In conclusion, the current study showed that oral administration of ginger and thyme aqueous extracts to growing rabbits showed no adverse effects on liver and kidney function parameters, histological structures and improved antioxidant status.
(© 2019 Blackwell Verlag GmbH.)
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فهرسة مساهمة: Keywords: antioxidant; ginger; kidney; liver; rabbits; thyme
المشرفين على المادة: 0 (Antioxidants)
تواريخ الأحداث: Date Created: 20190824 Date Completed: 20200423 Latest Revision: 20240109
رمز التحديث: 20240109
DOI: 10.1111/jpn.13166
PMID: 31441113
قاعدة البيانات: MEDLINE
الوصف
تدمد:1439-0396
DOI:10.1111/jpn.13166