دورية أكاديمية
Cell-independent matrix configuration in early corneal development.
العنوان: | Cell-independent matrix configuration in early corneal development. |
---|---|
المؤلفون: | Young RD; Structural Biophysics Group, School of Optometry & Vision Sciences, Cardiff University, Maindy Road, Cathays, Cardiff, CF24 4HQ, Wales, UK. Electronic address: youngrd@cardiff.ac.uk., Knupp C; Structural Biophysics Group, School of Optometry & Vision Sciences, Cardiff University, Maindy Road, Cathays, Cardiff, CF24 4HQ, Wales, UK. Electronic address: knuppC@cardiff.ac.uk., Koudouna E; Structural Biophysics Group, School of Optometry & Vision Sciences, Cardiff University, Maindy Road, Cathays, Cardiff, CF24 4HQ, Wales, UK. Electronic address: koudounaE@cardiff.ac.uk., Ralphs JR; School of Biosciences, Cardiff University, Sir Martin Evans Building, Museum Avenue, Cardiff, CF10 3AX, Wales, UK. Electronic address: ralphs@cardiff.ac.uk., Ma Y; Department of Biomedical Engineering, Ohio State University, 1080 Carmack Road, Columbus, OH 43210, USA. Electronic address: Ma.1634@osu.edu., Lwigale PY; Department of Biosciences, Rice University, 6100 Main Street, Houston, TX, 77005, USA. Electronic address: pl7@rice.edu., Jester JV; Departments of Ophthalmology and Biomedical Engineering, University of California, 843 Health Sciences Road, Irvine, CA, 92697, USA. Electronic address: jjester@uci.edu., Quantock AJ; Structural Biophysics Group, School of Optometry & Vision Sciences, Cardiff University, Maindy Road, Cathays, Cardiff, CF24 4HQ, Wales, UK. Electronic address: QuantockAJ@cf.ac.uk. |
المصدر: | Experimental eye research [Exp Eye Res] 2019 Oct; Vol. 187, pp. 107772. Date of Electronic Publication: 2019 Aug 21. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Academic Press Country of Publication: England NLM ID: 0370707 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0007 (Electronic) Linking ISSN: 00144835 NLM ISO Abbreviation: Exp Eye Res Subsets: MEDLINE |
أسماء مطبوعة: | Publication: London : Academic Press Original Publication: London. |
مواضيع طبية MeSH: | Cornea/*embryology , Extracellular Matrix/*ultrastructure, Animals ; Chick Embryo ; Chondroitin Sulfates/metabolism ; Collagen Type I/metabolism ; Collagen Type II/metabolism ; Cornea/metabolism ; Cornea/ultrastructure ; Corneal Stroma/embryology ; Corneal Stroma/metabolism ; Corneal Stroma/ultrastructure ; Dermatan Sulfate/metabolism ; Extracellular Matrix/metabolism ; Fourier Analysis ; Imaging, Three-Dimensional ; Microscopy, Electron, Scanning ; Microscopy, Electron, Transmission ; Morphogenesis/physiology |
مستخلص: | Mechanisms controlling the spatial configuration of the remarkably ordered collagen-rich extracellular matrix of the transparent cornea remain incompletely understood. We previously described the assembly of the emerging corneal matrix in the mid and late stages of embryogenesis and concluded that collagen fibril organisation was driven by cell-directed mechanisms. Here, the early stages of corneal morphogenesis were examined by serial block face scanning electron microscopy of embryonic chick corneas starting at embryonic day three (E3), followed by a Fourier transform analysis of three-dimensional datasets and theoretical considerations of factors that influence matrix formation. Eyes developing normally and eyes that had the lens surgically removed at E3 were studied. Uniformly thin collagen fibrils are deposited by surface ectoderm-derived corneal epithelium in the primary stroma of the developing chick cornea and form an acellular matrix with a striking micro-lamellar orthogonal arrangement. Fourier transform analysis supported this observation and indicated that adjacent micro-lamellae display a clockwise rotation of fibril orientation, depth-wise below the epithelium. We present a model which attempts to explain how, in the absence of cells in the primary stroma, collagen organisation might be influenced by cell-independent, intrinsic mechanisms, such as fibril axial charge derived from associated proteoglycans. On a supra-lamellar scale, fine cords of non-collagenous filamentous matrix were detected over large tissue volumes. These extend into the developing cornea from the epithelial basal lamina and appear to associate with the neural crest cells that migrate inwardly to form, first the corneal endothelium and then keratocytes which synthesise the mature, secondary corneal stroma. In a small number of experimental specimens, matrix cords were present even when periocular neural crest cell migration and corneal morphogenesis had been perturbed following removal of the lens at E3. (Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.) |
References: | Invest Ophthalmol Vis Sci. 1988 Jan;29(1):101-7. (PMID: 2447029) Biophys J. 2005 Feb;88(2):1377-86. (PMID: 15533922) Nat Protoc. 2011 Jun;6(6):845-58. (PMID: 21637203) J Cell Sci. 2011 Dec 1;124(Pt 23):4096-105. (PMID: 22159420) Acta Biomater. 2018 Oct 1;79:96-112. (PMID: 30170195) Dev Dyn. 2010 Mar;239(3):844-54. (PMID: 20108350) Sci Rep. 2019 Aug 2;9(1):11277. (PMID: 31375736) Biol Cell. 1989;67(1):97-101. (PMID: 2605377) J Biomech. 2003 Jan;36(1):97-102. (PMID: 12485643) Matrix Biol. 2003 Nov;22(6):467-75. (PMID: 14667839) Science. 1980 Apr 11;208(4440):177-9. (PMID: 6987736) J Cell Biol. 1984 Dec;99(6):2024-33. (PMID: 6542105) Matrix Biol. 2017 Dec;64:81-93. (PMID: 28882761) Dev Dyn. 2001 Mar;220(3):284-9. (PMID: 11241836) Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):687-92. (PMID: 24385584) Dev Dyn. 1995 Jan;202(1):42-53. (PMID: 7703520) Proc Natl Acad Sci U S A. 1988 Oct;85(20):7496-7500. (PMID: 3050996) Prog Retin Eye Res. 2018 May;64:65-76. (PMID: 29398348) Matrix Biol. 2006 Jan;25(1):3-13. (PMID: 16253492) Invest Ophthalmol Vis Sci. 2001 Jul;42(8):1750-6. (PMID: 11431438) Structure. 2010 Feb 10;18(2):239-45. (PMID: 20159468) J Biochem. 1995 Apr;117(4):707-18. (PMID: 7592530) Exp Cell Res. 1991 Aug;195(2):432-42. (PMID: 2070825) J Cell Sci. 1990 Apr;95 ( Pt 4):649-57. (PMID: 2384532) Exp Eye Res. 2015 Apr;133:49-57. (PMID: 25819454) Dev Dyn. 2019 Jul;248(7):583-602. (PMID: 31004457) Exp Eye Res. 2010 Sep;91(3):326-35. (PMID: 20599432) Invest Ophthalmol Vis Sci. 2000 Oct;41(11):3365-73. (PMID: 11006226) Dev Biol. 2007 Jun 15;306(2):750-9. (PMID: 17499699) Exp Eye Res. 2015 Apr;133:69-80. (PMID: 25819456) Biochem J. 1980 Jun 1;187(3):887-91. (PMID: 7188429) Invest Ophthalmol Vis Sci. 2010 Mar;51(3):1365-72. (PMID: 19815728) J Cell Biol. 1971 Sep;50(3):840-58. (PMID: 4329158) Prog Retin Eye Res. 1998 Apr;17(2):231-65. (PMID: 9695794) J Biol Chem. 2003 Jun 13;278(24):21672-7. (PMID: 12665512) Biophys J. 2012 Jul 18;103(2):357-64. (PMID: 22853914) Dev Dyn. 1994 Nov;201(3):206-15. (PMID: 7881125) Proc Natl Acad Sci U S A. 1985 May;82(9):2608-12. (PMID: 3857602) Biomaterials. 2012 Oct;33(30):7366-74. (PMID: 22846420) Monogr Dev Biol. 1969;1:1-144. (PMID: 5407672) PLoS Biol. 2004 Nov;2(11):e329. (PMID: 15514700) J Biol Chem. 2009 Mar 27;284(13):8888-97. (PMID: 19136671) Dev Dyn. 2008 Oct;237(10):2607-21. (PMID: 18521942) Dev Biol. 1991 Apr;144(2):379-91. (PMID: 2010037) J Cell Biochem. 2002;87(2):208-20. (PMID: 12244573) J Biol Chem. 1986 Dec 15;261(35):16281-3. (PMID: 3097005) J Neurosci. 2008 Mar 19;28(12):2959-64. (PMID: 18353998) Biomaterials. 2016 Aug;97:74-84. (PMID: 27162076) Int J Mol Sci. 2017 Aug 15;18(8):. (PMID: 28809791) |
معلومات مُعتمدة: | MR/K000837/1 United Kingdom MRC_ Medical Research Council |
فهرسة مساهمة: | Keywords: Collagen; Cornea; Development; Serial block face scanning electron microscopy |
المشرفين على المادة: | 0 (Collagen Type I) 0 (Collagen Type II) 24967-94-0 (Dermatan Sulfate) 9007-28-7 (Chondroitin Sulfates) |
تواريخ الأحداث: | Date Created: 20190825 Date Completed: 20200228 Latest Revision: 20210110 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC6892249 |
DOI: | 10.1016/j.exer.2019.107772 |
PMID: | 31445001 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1096-0007 |
---|---|
DOI: | 10.1016/j.exer.2019.107772 |