دورية أكاديمية

Antibiotic Hypersensitivity Mechanisms.

التفاصيل البيبلوغرافية
العنوان: Antibiotic Hypersensitivity Mechanisms.
المؤلفون: Maker JH; Department of Pharmacy Practice, Thomas J Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, CA 95211, USA. jmaker@pacific.edu., Stroup CM; Department of Pharmacy Practice, School of Pharmacy, Rueckert-Hartman College of Health Professions, Regis University, Denver, CO 80221, USA., Huang V; Department of Pharmacy Practice, College of Pharmacy-Glendale, Midwestern University, Glendale, AZ 85308, USA., James SF; Department of Pharmaceutical Sciences, School of Pharmacy, Rueckert-Hartman College of Health Professions, Regis University, Denver, CO 80221, USA.
المصدر: Pharmacy (Basel, Switzerland) [Pharmacy (Basel)] 2019 Aug 27; Vol. 7 (3). Date of Electronic Publication: 2019 Aug 27.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101678532 Publication Model: Electronic Cited Medium: Internet ISSN: 2226-4787 (Electronic) Linking ISSN: 22264787 NLM ISO Abbreviation: Pharmacy (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, [2013]-
مستخلص: Antibiotics are commonly prescribed to treat a variety of bacterial infections. As with all medications, hypersensitivity reactions may occur and clinicians should be able to recognize them accurately and recommend appropriate management. Antibiotic related hypersensitivity reactions may be one of four different types: Type I reactions, which are IgE mediated and may lead to anaphylaxis; Type II reactions that are antibody-mediated and may result in thrombocytopenia, neutropenia, or hemolytic anemia; Type III reaction that involves an immune complex formation such as vasculitis; and Type IV reactions that consist of four subtypes and typically include a rash of varying level of severity with or without systemic signs and symptoms. Herein, we describe the mechanisms of different types of allergic reactions to commonly prescribed antibiotics and offer recommendations for management. Further, we briefly refer to antibiotic reactions that mimic hypersensitivity reactions but are not immune mediated, such as pseudoallergies and serum sickness-like reactions.
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فهرسة مساهمة: Keywords: Type I; Type II; Type III; Type IV; allergy; anaphylaxis; antibiotic; antimicrobial; hypersensitivity
تواريخ الأحداث: Date Created: 20190830 Latest Revision: 20240720
رمز التحديث: 20240720
مُعرف محوري في PubMed: PMC6789858
DOI: 10.3390/pharmacy7030122
PMID: 31461919
قاعدة البيانات: MEDLINE
الوصف
تدمد:2226-4787
DOI:10.3390/pharmacy7030122