دورية أكاديمية
أعرض في EDS

Effects of postbiotic supplementation on growth performance, ruminal fermentation and microbial profile, blood metabolite and GHR, IGF-1 and MCT-1 gene expression in post-weaning lambs.

التفاصيل البيبلوغرافية
العنوان: Effects of postbiotic supplementation on growth performance, ruminal fermentation and microbial profile, blood metabolite and GHR, IGF-1 and MCT-1 gene expression in post-weaning lambs.
المؤلفون: Izuddin WI; Department of Animal Science, Faculty of Agriculture, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia., Loh TC; Department of Animal Science, Faculty of Agriculture, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. tcloh@upm.edu.my.; Institute of Tropical Agriculture and Food Security, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. tcloh@upm.edu.my., Samsudin AA; Department of Animal Science, Faculty of Agriculture, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.; Institute of Tropical Agriculture and Food Security, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia., Foo HL; Department of Bioprocess Technology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. hlfoo@upm.edu.my.; Institute of Bioscience, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. hlfoo@upm.edu.my., Humam AM; Department of Animal Science, Faculty of Agriculture, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.; Department of Animal Resources, Faculty of Agriculture, University of Baghdad, Baghdad, Iraq., Shazali N; Department of Animal Science, Faculty of Agriculture, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
المصدر: BMC veterinary research [BMC Vet Res] 2019 Sep 02; Vol. 15 (1), pp. 315. Date of Electronic Publication: 2019 Sep 02.
نوع المنشور: Clinical Trial, Veterinary; Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101249759 Publication Model: Electronic Cited Medium: Internet ISSN: 1746-6148 (Electronic) Linking ISSN: 17466148 NLM ISO Abbreviation: BMC Vet Res Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, 2005-
مواضيع طبية MeSH: Dietary Supplements*, Insulin-Like Growth Factor I/*metabolism , Monocarboxylic Acid Transporters/*metabolism , Receptors, Somatotropin/*metabolism , Sheep/*growth & development, Animal Feed/analysis ; Animal Nutritional Physiological Phenomena ; Animals ; Diet/veterinary ; Digestion ; Fermentation ; Gene Expression Regulation/drug effects ; Insulin-Like Growth Factor I/genetics ; Lactobacillus plantarum ; Male ; Monocarboxylic Acid Transporters/genetics ; Random Allocation ; Receptors, Somatotropin/genetics ; Rumen/microbiology ; Sheep/blood ; Sheep/metabolism ; Weaning
مستخلص: Background: Postbiotics have been established as potential feed additive to be used in monogastric such as poultry and swine to enhance health and growth performance. However, information on the postbiotics as feed additive in ruminants is very limited. The aim of this study was to elucidate the effects of supplementation of postbiotics in newly-weaned lambs on growth performance, digestibility, rumen fermentation characteristics and microbial population, blood metabolite and expression of genes related to growth and volatile fatty acid transport across the rumen epithelium.
Results: Postbiotic supplementation increased weight gain, feed intake, nutrient intake and nutrient digestibility of the lambs. No effect on ruminal pH and total VFA, whereas butyrate and ruminal ammonia-N concentration were improved. The lambs fed with postbiotics had higher blood total protein, urea nitrogen and glucose. However, no difference was observed in blood triglycerides and cholesterol levels. Postbiotics increased the population of fibre degrading bacteria but decreased total protozoa and methanogens in rumen. Postbiotics increased the mRNA expression of hepatic IGF-1 and ruminal MCT-1.
Conclusions: The inclusion of postbiotics from L. plantarum RG14 in newly-weaned lambs improved growth performance, nutrient intake and nutrient digestibility reflected from better rumen fermentation and microbial parameters, blood metabolites and upregulation of growth and nutrient intake genes in the post-weaning lambs.
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فهرسة مساهمة: Keywords: Blood metabolite; Gene expression; Growth performance; Lactobacillus plantarum; Nutrient uptake; Post-weaning lambs; Postbiotics; Rumen fermentation
المشرفين على المادة: 0 (Monocarboxylic Acid Transporters)
0 (Receptors, Somatotropin)
67763-96-6 (Insulin-Like Growth Factor I)
تواريخ الأحداث: Date Created: 20190904 Date Completed: 20191209 Latest Revision: 20200225
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC6719353
DOI: 10.1186/s12917-019-2064-9
PMID: 31477098
قاعدة البيانات: MEDLINE
الوصف
تدمد:1746-6148
DOI:10.1186/s12917-019-2064-9