دورية أكاديمية
Maternal history of asthma modifies the risk of childhood persistent asthma associated with maternal age at birth: Results from a large prospective cohort in Canada.
| العنوان: | Maternal history of asthma modifies the risk of childhood persistent asthma associated with maternal age at birth: Results from a large prospective cohort in Canada. |
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| المؤلفون: | Wadden D; Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada., Farrell J; Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada., Smith MJ; Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada., Twells LK; Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada., Gao Z; Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada. |
| المصدر: | The Journal of asthma : official journal of the Association for the Care of Asthma [J Asthma] 2021 Jan; Vol. 58 (1), pp. 38-45. Date of Electronic Publication: 2019 Sep 03. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 8106454 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-4303 (Electronic) Linking ISSN: 02770903 NLM ISO Abbreviation: J Asthma Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Informa Healthcare Original Publication: [Ossining, N.Y. : Asthma Publications Society, c1981- |
| مواضيع طبية MeSH: | Maternal Age*, Asthma/*epidemiology, Canada ; Child ; Cohort Studies ; Female ; Humans ; Male ; Prospective Studies ; Risk Assessment |
| مستخلص: | Background: Asthma is a prevalent disease that affects many Canadians. Persistent asthma can affect quality of life, and has multiple health implications. Maternal age at birth has been associated with many adverse health outcomes in children. Conflicting study results exist regarding maternal age at birth and childhood asthma. The association between maternal age at birth and persistent asthma in children is still unknown. Objective: To investigate the relationship between maternal age at birth and persistent asthma in children at ten years of age. Methods: This is a prospective cohort study including all children aged 0-2 years who took part in the first cycle of the National Longitudinal Survey of Children and Youths (NLSCY) and were followed every two years until eight to ten years of age in Cycle 5. An interaction term between maternal age at birth and maternal asthma history was introduced in a multivariate model to examine modification effects of maternal asthma history on the association. Results: Multivariate logistic regression demonstrated that older maternal age at birth was significantly associated with an increased risk of childhood persistent asthma in mothers with a history of asthma (OR = 1.20, 95% CI: 1.04-1.40, p = .016). No relationship was found in mothers without a history of asthma. Conclusion: Maternal history of asthma has an impact on the association between maternal age at birth and childhood persistent asthma in children by age ten. The finding may help explain the inconsistent results in the literature regarding the risk of asthma associated with maternal age at birth. |
| فهرسة مساهمة: | Keywords: Asthma; Canada; childhood |
| تواريخ الأحداث: | Date Created: 20190904 Date Completed: 20210916 Latest Revision: 20210916 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1080/02770903.2019.1658207 |
| PMID: | 31479289 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1532-4303 |
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| DOI: | 10.1080/02770903.2019.1658207 |