دورية أكاديمية
Hematopoietic Stem Cell Transplantation in Solid Organ Recipients with Emphasis on Transplant Complications: A Nationwide Retrospective Survey on Behalf of the Japan Society for Hematopoietic Stem Cell Transplantation Transplant Complications Working Group.
| العنوان: | Hematopoietic Stem Cell Transplantation in Solid Organ Recipients with Emphasis on Transplant Complications: A Nationwide Retrospective Survey on Behalf of the Japan Society for Hematopoietic Stem Cell Transplantation Transplant Complications Working Group. |
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| المؤلفون: | Shinohara A; Department of Hematology, Tokyo Women's Medical University, Tokyo, Japan. Electronic address: sinohaa-tky@umin.ac.jp., Oshima K; Department of Hematology, Jyoban Hospital, Tokiwa Foundation, Fukushima, Japan., Fuji S; Department of Hematology, Osaka International Cancer Institute, Osaka, Japan., Umeda K; Department of Pediatrics, Kyoto University Hospital, Kyoto, Japan., Kako S; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan., Kurokawa M; Department of Cell Therapy and Transplantation Medicine, The University of Tokyo, Tokyo, Japan., Tsukada N; Division of Hematology, Japanese Red Cross Medical Center, Tokyo, Japan., Kasai M; Department of Hematology and Oncology, Nagoya Daini Red Cross Hospital, Aichi, Japan., Kondo T; Department of Hematology, Kyoto University Hospital, Kyoto, Japan., Hashii Y; Department of Cancer Immunotherapy, Graduate School of Medicine, Osaka University, Osaka, Japan., Nakamae H; Department of Hematology, Osaka City University Hospital, Osaka, Japan., Ikegame K; Division of Hematology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan., Kosaka Y; Department of Hematology and Oncology, Center of Childhood Cancer, Hyogo Prefectural Kobe Children's Hospital, Hyogo, Japan., Shimada A; Department of Pediatrics, Okayama University Hospital, Okayama, Japan., Nawa Y; Division of Hematology, Ehime Prefectural Central Hospital, Ehime, Japan., Makoto Y; Department of Hematology and Immunology, Kagoshima University Hospital, Kagoshima, Japan., Yoshiko A; The Japanese Data Center for Hematopoietic Cell Transplantation, Aichi, Japan., Fukuda T; National Cancer Center Hospital, Hematopoietic Stem Cell Transplantation Division, Tokyo, Japan., Tanaka J; Department of Hematology, Tokyo Women's Medical University, Tokyo, Japan., Ogata M; Department of Hematology, Oita University Hospital, Oita, Japan. |
| المصدر: | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation [Biol Blood Marrow Transplant] 2020 Jan; Vol. 26 (1), pp. 66-75. Date of Electronic Publication: 2019 Sep 05. |
| نوع المنشور: | Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Carden Jennings Publishing Country of Publication: United States NLM ID: 9600628 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-6536 (Electronic) Linking ISSN: 10838791 NLM ISO Abbreviation: Biol Blood Marrow Transplant Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Charlottesville, VA : Carden Jennings Publishing Original Publication: Charlottesville, VA : Kluge Carden Jennings Publishing, Co., Ltd., [1995- |
| مواضيع طبية MeSH: | Graft Rejection*/mortality , Graft Rejection*/prevention & control , Hematopoietic Stem Cell Transplantation* , Kidney Transplantation* , Liver Transplantation*, Adolescent ; Adult ; Child ; Child, Preschool ; Disease-Free Survival ; Female ; Humans ; Infant ; Japan/epidemiology ; Male ; Middle Aged ; Societies, Medical ; Survival Rate ; Transplantation, Autologous ; Transplantation, Homologous |
| مستخلص: | Little is known about stem cell transplantation in solid organ transplantation (SOT) recipients. We conducted a nationwide retrospective survey of Japan Society for Hematopoietic Stem Cell Transplantation centers. A total of 19 patients who underwent 22 hematopoietic stem cell transplantations (HSCTs) after SOT were identified: 5 autologous HSCTs and 17 allogeneic HSCTs were performed. Patients who underwent autologous HSCT received a liver (n = 4) or kidney (n = 1) transplant. All 5 patients achieved neutrophil engraftment, and 2 of 3 patients with hepatoblastoma were alive at 1 year after HSCT. Allogeneic HSCT was performed in 16 patients (7 liver transplant recipients and 9 kidney transplant recipients). Among these, 2 donors were identical for both transplantations. All but 1 patient achieved neutrophil engraftment. The 5-year overall survival rate was 41.7%, but that in patients with malignant disease (n = 13) was much lower than the overall rate (23.1%). Only 1 patient with malignant disease underwent allogeneic HSCT in nonremission. In allogeneic HSCT after kidney transplantation, post-transplantation (1 year) kidney function in 5 evaluable patients was significantly lower than that before allogeneic HSCT, and 3 patients experienced renal rejection. However, no severe hepatic rejection was noted. In SOT recipients, HSCT is a potentially curable treatment for hematologic disorders, but it must be performed with caution, especially in patients with malignancy. (Copyright © 2019 American Society for Transplantation and Cellular Therapy. Published by Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Hematopoietic stem cell transplantation; Liver failure; Renal failure; Solid organ transplantation; Transplantation-related complications |
| تواريخ الأحداث: | Date Created: 20190909 Date Completed: 20210121 Latest Revision: 20210121 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.bbmt.2019.08.021 |
| PMID: | 31494230 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1523-6536 |
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| DOI: | 10.1016/j.bbmt.2019.08.021 |