دورية أكاديمية
أعرض في EDS

Geographical location influences the composition of the gut microbiota in wild house mice (Mus musculus domesticus) at a fine spatial scale.

التفاصيل البيبلوغرافية
العنوان: Geographical location influences the composition of the gut microbiota in wild house mice (Mus musculus domesticus) at a fine spatial scale.
المؤلفون: Goertz S; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom., de Menezes AB; School of Natural Sciences, NUI Galway, Galway, Ireland., Birtles RJ; School of Environment and Life Sciences, University of Salford, Manchester, United Kingdom., Fenn J; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom., Lowe AE; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom., MacColl ADC; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom., Poulin B; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom., Young S; IUCN SSC Asian Wild Cattle Specialist Group, c/o Chester Zoo, Chester, United Kingdom., Bradley JE; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom., Taylor CH; School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
المصدر: PloS one [PLoS One] 2019 Sep 26; Vol. 14 (9), pp. e0222501. Date of Electronic Publication: 2019 Sep 26 (Print Publication: 2019).
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Gastrointestinal Microbiome*, Mice/*microbiology, Animals ; Ecosystem ; Environment ; Female ; Geography ; Islands ; Male ; Scotland
مستخلص: The composition of the mammalian gut microbiota can be influenced by a multitude of environmental variables such as diet and infections. Studies investigating the effect of these variables on gut microbiota composition often sample across multiple separate populations and habitat types. In this study we explore how variation in the gut microbiota of the house mouse (Mus musculus domesticus) on the Isle of May, a small island off the east coast of Scotland, is associated with environmental and biological factors. Our study focuses on the effects of environmental variables, specifically trapping location and surrounding vegetation, as well as the host variables sex, age, body weight and endoparasite infection, on the gut microbiota composition across a fine spatial scale in a freely interbreeding population. We found that differences in gut microbiota composition were significantly associated with the trapping location of the host, even across this small spatial scale. Sex of the host showed a weak association with microbiota composition. Whilst sex and location could be identified as playing an important role in the compositional variation of the gut microbiota, 75% of the variation remains unexplained. Whereas other rodent studies have found associations between gut microbiota composition and age of the host or parasite infections, the present study could not clearly establish these associations. We conclude that fine spatial scales are important when considering gut microbiota composition and investigating differences among individuals.
Competing Interests: The authors have declared that no competing interests exist.
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معلومات مُعتمدة: BB/J014508/1 United Kingdom BB_ Biotechnology and Biological Sciences Research Council
تواريخ الأحداث: Date Created: 20190927 Date Completed: 20200311 Latest Revision: 20240720
رمز التحديث: 20240720
مُعرف محوري في PubMed: PMC6767902
DOI: 10.1371/journal.pone.0222501
PMID: 31557179
قاعدة البيانات: MEDLINE
الوصف
تدمد:1932-6203
DOI:10.1371/journal.pone.0222501