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Diagnostic value of dipstick test in adult symptomatic urinary tract infections: results of a cross-sectional Tunisian study.

التفاصيل البيبلوغرافية
العنوان: Diagnostic value of dipstick test in adult symptomatic urinary tract infections: results of a cross-sectional Tunisian study.
المؤلفون: Bellazreg F; Department of Infectious Diseases, Farhat Hached Hospital, Sousse, Tunisia., Abid M; Department of Infectious Diseases, Farhat Hached Hospital, Sousse, Tunisia., Lasfar NB; Department of Infectious Diseases, Farhat Hached Hospital, Sousse, Tunisia., Hattab Z; Department of Infectious Diseases, Farhat Hached Hospital, Sousse, Tunisia., Hachfi W; Department of Infectious Diseases, Farhat Hached Hospital, Sousse, Tunisia., Letaief A; Department of Infectious Diseases, Farhat Hached Hospital, Sousse, Tunisia.
المصدر: The Pan African medical journal [Pan Afr Med J] 2019 Jun 21; Vol. 33, pp. 131. Date of Electronic Publication: 2019 Jun 21 (Print Publication: 2019).
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Kampala, Uganda : African Field Epidemiology Network
مواضيع طبية MeSH: Carboxylic Ester Hydrolases/*urine , Escherichia coli Infections/*diagnosis , Nitrites/*urine , Urinary Tract Infections/*diagnosis, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Bacteriuria/diagnosis ; Bacteriuria/microbiology ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Reagent Strips ; Sensitivity and Specificity ; Tunisia ; Urinalysis/methods ; Urinary Tract Infections/microbiology ; Young Adult
مستخلص: Urinary tract infections (UTIs) are common. The diagnosis is confirmed by urine culture which is costly and takes at least 24 hours before results are known. The aim of this study was to determine the diagnostic accuracy of dipstick test for the diagnosis of UTI in symptomatic adult patients. We conducted a cross-sectional study in the department of Infectious Diseases, Sousse-Tunisia during a two-year period. We included all patients with clinical signs of UTI. Urine samples were tested for the presence of leukocyte esterase (LE) and nitrites. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of LE and nitrites were calculated against urine culture as gold standard. Four hundred thirty one patients, 139 men (32%) and 292 women (68%) were included. One hundred sixty six patients (39%) had UTI. The most frequently isolated microorganism was Escherichia coli (75%). LE had a high sensitivity (87%) but a low specificity (64%), while nitrites had a high specificity (95%) but a low sensitivity (48%). Combined positive LE and nitrites had a high PPV (85%) and combined negative LE and nitrites had a high NPV (92%), while positive LE combined with negative nitrites had a low PPV (47%) and a low NPV (53%). In conclusion, in adult patients with UTI symptoms, an alternate diagnosis should be considered if the LE is negative, while an early empirical antibiotic therapy against Enterobacteriaceae should be started if the nitrites are positive.
Competing Interests: The authors declare no competing interests.
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فهرسة مساهمة: Keywords: Urinary tract infection; diagnosis; dipstick test; leukocyte esterase; nitrites
المشرفين على المادة: 0 (Nitrites)
0 (Reagent Strips)
EC 3.1.- (leukocyte esterase)
EC 3.1.1.- (Carboxylic Ester Hydrolases)
تواريخ الأحداث: Date Created: 20190928 Date Completed: 20191008 Latest Revision: 20200225
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC6754830
DOI: 10.11604/pamj.2019.33.131.17190
PMID: 31558930
قاعدة البيانات: MEDLINE
الوصف
تدمد:1937-8688
DOI:10.11604/pamj.2019.33.131.17190