دورية أكاديمية
أعرض في EDS

Relationship between blood lipid and arterial stiffness in hypertension.

التفاصيل البيبلوغرافية
العنوان: Relationship between blood lipid and arterial stiffness in hypertension.
المؤلفون: Si XB; Department of Cardiology, Beijing Hospital, National Center of Gerontology, Beijing, P.R. China; The Fourth Clinical College of Peking University, Beijing, P.R. China. email@email.com., Liu W
المصدر: Clinical and investigative medicine. Medecine clinique et experimentale [Clin Invest Med] 2019 Sep 29; Vol. 42 (3), pp. E47-E55. Date of Electronic Publication: 2019 Sep 29.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Canadian Society for Clinical Investigation Country of Publication: Canada NLM ID: 7804071 Publication Model: Electronic Cited Medium: Internet ISSN: 1488-2353 (Electronic) Linking ISSN: 0147958X NLM ISO Abbreviation: Clin Invest Med Subsets: MEDLINE
أسماء مطبوعة: Publication: 2005- : Ottawa : Canadian Society for Clinical Investigation
Original Publication: Oxford, New York : Pergamon Press
مواضيع طبية MeSH: Blood Pressure* , Hypertension*/blood , Hypertension*/physiopathology , Vascular Stiffness*, Lipids/*blood, Age Factors ; Aged ; Body Mass Index ; Coronary Artery Disease/blood ; Coronary Artery Disease/physiopathology ; Diabetes Mellitus/blood ; Diabetes Mellitus/physiopathology ; Dyslipidemias/blood ; Dyslipidemias/physiopathology ; Female ; Heart Rate ; Humans ; Male ; Middle Aged ; Retrospective Studies
مستخلص: Purpose: To explore the relationship between blood lipids and pulse wave velocity (PWV).
Methods: We retrospectively selected subjects who had undergone treatment in an outpatient or inpatient clinic. The subjects were sub-grouped into four groups: Group A (no history of hypertension and dyslipidemia), Group B (a history of dyslipidemia but not hypertension), Group C (a history of hypertension but not dyslipidemia) and Group D (a history of both hypertension and dyslipidemia). We determined brachial-ankle pulse wave velocity (baPWV), atherogenic index of plasma (AIP), non-high-density lipoprotein (non-HDL-C), total cholesterol/high density lipoprotein (TC/HDL-C) and atherogenic indices (AI) for hypertension and non-hypertension and dyslipidemia and non-dyslipidemia patients.
Results: A total of 380 subjects were included. Uric acid, systolic pressure, diastolic pressure, pulse pressure and mean arterial pressure were significantly different among the groups. The prevalence of coronary arterial disease and diabetes mellitus, age, body mass index, heart rate, blood glucose, creatinine, urea, smoking history and alcohol consumption did not differ among groups. The baPWV was significantly different between both hypertension/nonhypertension and dyslipidemia/non-dyslipidemia patients. In hypertension patients (in Group C and D), partial correlation analysis showed that ΔbaPWV correlated with TC, HDL-C, AI, AIP and TC/HDL-C but not LDL-C, triglyceride (TG) or non-HDL-C.
Conclusion: Hypertension and/or dyslipidemia may be risk factors for arterial stiffness. In hypertension patients, TC, HDL-C, AIP, AI and TC/HDL-C might correlate to arterial stiffness and pathological increases in these levels may indicate risk factors for arterial stiffness.
المشرفين على المادة: 0 (Lipids)
تواريخ الأحداث: Date Created: 20190930 Date Completed: 20200731 Latest Revision: 20200731
رمز التحديث: 20240628
DOI: 10.25011/cim.v42i3.33092
PMID: 31563160
قاعدة البيانات: MEDLINE
الوصف
تدمد:1488-2353
DOI:10.25011/cim.v42i3.33092