دورية أكاديمية
Phadiatop, Phadiatop Infant and total IgE evaluated in allergic Brazilian children and adolescents.
| العنوان: | Phadiatop, Phadiatop Infant and total IgE evaluated in allergic Brazilian children and adolescents. |
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| المؤلفون: | Pierotti FF; Federal University of São Paulo, São Paulo, SP, Brazil., Aranda CS; Federal University of São Paulo, São Paulo, SP, Brazil. Electronic address: carolaaranda@yahoo.com.br., Cocco RR; Federal University of São Paulo, São Paulo, SP, Brazil., Sarinho E; Federal University of Pernambuco, Pernambuco, Brazil., Sano F; Nipo-Brasileiro Hospital, São Paulo, Brazil., Porto A; University of Passo Fundo, Rio Grande do Sul, Brazil., Rosário N; Federal University of Paraná, Paraná, Brazil., Chong Neto HJ; Federal University of Paraná, Paraná, Brazil., Goudouris E; Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Moraes LS; Federal University of Mato Grosso, Mato Grosso, Brazil., Wandalsen NF; Medical University of Santo André, São Paulo, Brazil., Mallozi MC; Medical University of Santo André, São Paulo, Brazil., Pastorino AC; University of São Paulo, São Paulo, Brazil., Franco JM; Federal University of Sergipe, Sergipe, Brazil., Chavarria ML; Federal University of Goias, Goiás, Brazil., Borres MP; Uppsala University, Women's and Children's Health, Uppsala, Sweden and Thermo Fisher Scientific, Uppsala, Sweden., Solé D; Federal University of São Paulo, São Paulo, SP, Brazil. Electronic address: sole.dirceu@gmail.com. |
| المصدر: | Allergologia et immunopathologia [Allergol Immunopathol (Madr)] 2020 May - Jun; Vol. 48 (3), pp. 259-264. Date of Electronic Publication: 2019 Oct 07. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Codon Publications Country of Publication: Singapore NLM ID: 0370073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1578-1267 (Electronic) Linking ISSN: 03010546 NLM ISO Abbreviation: Allergol Immunopathol (Madr) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2021- : [Singapore] : Codon Publications Original Publication: Madrid : Elsevier España |
| مواضيع طبية MeSH: | Age Factors*, Hypersensitivity/*diagnosis , Skin Tests/*methods, Adolescent ; Allergens/immunology ; Brazil/epidemiology ; Child ; Child, Preschool ; Cross-Sectional Studies ; Female ; Humans ; Hypersensitivity/epidemiology ; Immunoglobulin E/metabolism ; Infant ; Male ; Prevalence |
| مستخلص: | The clinical history is of importance in the investigation of allergic diseases but does have limitations. Many allergic conditions will be over-diagnosed if anamnesis alone is used for diagnostic criteria. Serum total immunoglobulin E (TIgE) quantification, as well as panels containing allergens prevalent in the studied population, may serve as screening tests and facilitate the diagnosis of allergic disease or its exclusion. We assessed the positivity of two versions of these tests, Phadiatop Europe® (PhEU) and Phadiatop Infant® (PhInf), as well as total IgE (TigE) values in patients with a medical diagnosis of allergic disease and non-allergic individuals. Methods: A cross-sectional study performed in eleven Brazilian pediatric allergy centers with patients divided into groups according to the primary condition and a group of assessed control subjects. They were submitted to TIgE measurement and screening tests (PhEu and PhInf). Results: TIgE mean serum levels were significantly higher among allergic patients, especially those with asthma/rhinitis or atopic dermatitis. The positivity of the screening tests, considering the total population, was 63.8% for PhEU and 72.6% for PhInf. These increased when we evaluated only the allergic subjects. The concordance index of the two tests was Kappa=0.7 and higher among those of greater age. Conclusions: In the assessed population, there were significantly higher levels among those with positive screening tests and PhInf showed better performance in the identification of sensitized individuals, regardless of age. This is the first study to evaluate Phadiatop and Phadiatop Infant in the same population. (Copyright © 2019 SEICAP. Published by Elsevier España, S.L.U. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Allergens; Child; Hypersensitivity; Immunoglobulin E; Screening tests |
| المشرفين على المادة: | 0 (Allergens) 37341-29-0 (Immunoglobulin E) |
| تواريخ الأحداث: | Date Created: 20191012 Date Completed: 20201225 Latest Revision: 20201225 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.aller.2019.06.013 |
| PMID: | 31601506 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1578-1267 |
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| DOI: | 10.1016/j.aller.2019.06.013 |