دورية أكاديمية

Treatment of acute rumen lactic acidosis with intravenous hypertonic sodium chloride or bicarbonate solutions followed by intraruminal water.

التفاصيل البيبلوغرافية
العنوان: Treatment of acute rumen lactic acidosis with intravenous hypertonic sodium chloride or bicarbonate solutions followed by intraruminal water.
المؤلفون: Santos MM; Department of Veterinary Clinics, Universidade Estadual de Londrina, Londrina, Brazil. Electronic address: maira_moreira04@yahoo.com.br., Bregadioli GC; Department of Veterinary Clinics, Universidade Estadual de Londrina, Londrina, Brazil., Santos LGC; Department of Veterinary Clinics, Universidade Estadual de Londrina, Londrina, Brazil., Curti JM; Department of Veterinary Clinics, Universidade Estadual de Londrina, Londrina, Brazil., Duarte CABG; Department of Veterinary Clinics, Universidade Estadual de Londrina, Londrina, Brazil., Cerri FM; Department of Veterinary Clinics, Universidade Estadual de Londrina, Londrina, Brazil., Pereira PFV; Department of Veterinary Clinics, Universidade Estadual de Londrina, Londrina, Brazil., Flaiban KKMC; Department of Preventive Veterinary Medicine, Universidade Estadual de Londrina, Londrina, Brazil. Electronic address: kkflaiban@uel.br., Filho JDR; Department of Veterinary Medicine, Universidade Federal de Viçosa, Viçosa, Brazil. Electronic address: dantas@ufv.br., Lisbôa JAN; Department of Veterinary Clinics, Universidade Estadual de Londrina, Londrina, Brazil. Electronic address: janlisboa@uel.br.
المصدر: Research in veterinary science [Res Vet Sci] 2020 Feb; Vol. 128, pp. 24-34. Date of Electronic Publication: 2019 Oct 24.
نوع المنشور: Comparative Study; Journal Article
اللغة: English
بيانات الدورية: Publisher: British Veterinary Association Country of Publication: England NLM ID: 0401300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2661 (Electronic) Linking ISSN: 00345288 NLM ISO Abbreviation: Res Vet Sci Subsets: MEDLINE
أسماء مطبوعة: Publication: London : British Veterinary Association
Original Publication: Oxford.
مواضيع طبية MeSH: Acidosis, Lactic/*veterinary , Bicarbonates/*administration & dosage , Saline Solution, Hypertonic/*administration & dosage , Sheep Diseases/*therapy , Sodium Chloride/*administration & dosage , Water/*administration & dosage, Acidosis, Lactic/therapy ; Animals ; Female ; Infusions, Intravenous/veterinary ; Random Allocation ; Rumen/physiopathology ; Sheep
مستخلص: The effectiveness of 7% hypertonic saline solution (HSS) and 6% hypertonic bicarbonate solution (HBS) followed by intraruminal water administration for the treatment of acute rumen lactic acidosis (ARLA) has not been evaluated yet. The hypothesis of the study is that treatment with HBS causes a faster correction of imbalances and clinical recovery than treatment with HSS. ARLA was induced in six healthy mature female sheep with sucrose twice. The sheep received both treatment regimens in a cross over design. After 18 h of induction, rumen lavage was performed and IV infusion of 7% HSS (4 mL/kg BW) or 6% HBS (6.7 mL/kg BW) was done over 5 min, followed by intraruminal administration of water (8% BW). The solutions provided 4.8 mmol/kg BW of sodium. Physical and laboratory tests were performed for 168 h. Both treatments increased plasma volume. After HSS treatment, pH and HCO 3 - returned to baseline values at 144 h and BE at 168 h. With HBS treatment, pH returned to baseline at 24 h, and HCO 3 - and BE at 48 h. In both treatments, the ruminal motility and the maximum hay intake were restored at 96 and 120 h, respectively. In conclusion, administration of HSS or HBS followed by intraruminal water corrects dehydration and mild-to-moderate metabolic acidosis in sheep with ARLA. Treatment with HBS promoted a faster correction of metabolic acidosis and could be indicated for the most severe cases.
(Copyright © 2019 Elsevier Ltd. All rights reserved.)
فهرسة مساهمة: Keywords: 6% sodium bicarbonate; 7% sodium chloride; Dehydration; Fluid therapy; Hyperosmotic solution; Metabolic acidosis
المشرفين على المادة: 0 (Bicarbonates)
0 (Saline Solution, Hypertonic)
059QF0KO0R (Water)
451W47IQ8X (Sodium Chloride)
تواريخ الأحداث: Date Created: 20191111 Date Completed: 20200402 Latest Revision: 20200402
رمز التحديث: 20240628
DOI: 10.1016/j.rvsc.2019.10.009
PMID: 31707097
قاعدة البيانات: MEDLINE
الوصف
تدمد:1532-2661
DOI:10.1016/j.rvsc.2019.10.009