تقرير
The Man with 2 Hearts: 25 Years from Heterotopic to Orthotopic Heart Transplantation.
| العنوان: | The Man with 2 Hearts: 25 Years from Heterotopic to Orthotopic Heart Transplantation. |
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| المؤلفون: | Godfrey EL, Kueht ML, Rana A, Frazier OH |
| المصدر: | Texas Heart Institute journal [Tex Heart Inst J] 2019 Jun 01; Vol. 46 (3), pp. 199-202. Date of Electronic Publication: 2019 Jun 01 (Print Publication: 2019). |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: published in the Cardiovascular Surgical Research Laboratories, Texas Heart Institute Country of Publication: United States NLM ID: 8214622 Publication Model: eCollection Cited Medium: Internet ISSN: 1526-6702 (Electronic) Linking ISSN: 07302347 NLM ISO Abbreviation: Tex Heart Inst J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Houston, TX : published in the Cardiovascular Surgical Research Laboratories, Texas Heart Institute, c1982- |
| مواضيع طبية MeSH: | Heart-Assist Devices*, Heart Failure/*therapy , Heart Transplantation/*methods , Intra-Aortic Balloon Pumping/*methods, Adolescent ; Follow-Up Studies ; Graft Survival ; Heart Failure/diagnosis ; Humans ; Male ; Time Factors ; Tomography, X-Ray Computed ; Transplantation, Heterotopic |
| مستخلص: | Substantial technological advances in mechanical circulatory support have caused a shift in the management of end-stage heart failure. From the 1970s through the 1990s, heterotopic heart transplantation was routinely performed in patients in whom orthotopic transplantation was likely to fail. Heterotopic heart transplantation is now performed less often because modern mechanical circulatory assist devices are routinely used as bridges to orthotopic transplantation; regardless, the operation has helped numerous patients who would not otherwise have received adequate allografts. We describe the case of a man with idiopathic nonischemic cardiomyopathy who, at age 17, was given an ABO- and size-matched heterotopic allograft that was a complete human leukocyte antigen mismatch. The graft functioned normally for 20 years until the patient had a myocardial infarction that necessitated placement of a coronary artery stent. Subsequent treatments involved many interventions, including insertion of an intra-aortic balloon pump, medical therapy for heart failure, implantation of a total artificial heart, and, ultimately, orthotopic transplantation. To our knowledge, our patient is the longest surviving recipient of a heterotopic heart transplant, with a remarkable 25-year graft survival despite poor histocompatibility and an almost complete lack of native heart function. The strategies used for his treatment make him a living case study that can add valuable information to the history of cardiac support. (© 2019 by the Texas Heart® Institute, Houston.) |
| References: | Exp Clin Transplant. 2013 Aug;11(4):346-51. (PMID: 23734843) J Heart Transplant. 1989 Sep-Oct;8(5):418-20; discussion 420-1. (PMID: 2795285) Rev Esp Cardiol (Engl Ed). 2019 Oct;72(10):835-843. (PMID: 30115570) J Heart Lung Transplant. 2010 Mar;29(3):368-70. (PMID: 20036164) J Heart Lung Transplant. 1992 May-Jun;11(3 Pt 2):S90-103. (PMID: 1623009) J Heart Lung Transplant. 2002 Aug;21(8):867-73. (PMID: 12163086) Eur J Cardiothorac Surg. 2016 Jan;49(1):348-9. (PMID: 25724904) Tex Heart Inst J. 1985 Sep;12(3):221-32. (PMID: 15227008) Hellenic J Cardiol. 2019 Feb 19;:null. (PMID: 30790715) N Engl J Med. 1994 Mar 24;330(12):816-9. (PMID: 8068075) World J Pediatr Congenit Heart Surg. 2011 Oct 1;2(4):637-40. (PMID: 23804478) Cardiol Clin. 2018 Nov;36(4):551-560. (PMID: 30297072) Am J Med. 2015 Jul;128(7):e7-8. (PMID: 25660251) Ann Thorac Surg. 2004 Oct;78(4):1345-50; discussion 1350-1. (PMID: 15464497) Eur Heart J. 2016 Nov 21;37(44):3356. (PMID: 27371717) Ann Emerg Med. 2012 Jul;60(1):67-70. (PMID: 22243958) Arch Inst Cardiol Mex. 1999 Nov-Dec;69(6):526-33. (PMID: 10742849) Transplantation. 1994 Sep 27;58(6):719-22. (PMID: 7940693) Transplantation. 1999 Aug 27;68(4):515-9. (PMID: 10480409) |
| فهرسة مساهمة: | Keywords: Follow-up studies; HLA antigens/analysis; graft survival; heart failure/surgery; heart transplantation/methods/physiology; reoperation; survival analysis; time factors; transplant recipients; transplantation, heterotopic; treatment outcome |
| تواريخ الأحداث: | Date Created: 20191112 Date Completed: 20200128 Latest Revision: 20200128 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC6827470 |
| DOI: | 10.14503/THIJ-17-6544 |
| PMID: | 31708703 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1526-6702 |
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| DOI: | 10.14503/THIJ-17-6544 |