دورية أكاديمية
Quality of Life and Traditional Outcome Results at 1 Year in Elderly Patients Having Critical Limb Ischemia and the Role of Conservative Treatment.
| العنوان: | Quality of Life and Traditional Outcome Results at 1 Year in Elderly Patients Having Critical Limb Ischemia and the Role of Conservative Treatment. |
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| المؤلفون: | Steunenberg SL; Department of Surgery, Amphia Hospital, Breda, the Netherlands., de Vries J; Department of Medical and Clinical Psychology, Tilburg University, Tilburg, the Netherlands., Raats JW; Department of Surgery, Amphia Hospital, Breda, the Netherlands., Verbogt N; Department of Surgery, Amphia Hospital, Breda, the Netherlands., Lodder P; Department of Medical and Clinical Psychology, Tilburg University, Tilburg, the Netherlands.; Department of Methodology and Statistics, Tilburg University, Tilburg, the Netherlands., van Eijck GJ; Department of Surgery, Bravis Hospital, Roosendaal, the Netherlands., Veen EJ; Department of Surgery, Amphia Hospital, Breda, the Netherlands., de Groot HGW; Department of Surgery, Amphia Hospital, Breda, the Netherlands., Ho GH; Department of Surgery, Amphia Hospital, Breda, the Netherlands., der Laan LV; Department of Surgery, Amphia Hospital, Breda, the Netherlands. |
| المصدر: | Vascular and endovascular surgery [Vasc Endovascular Surg] 2020 Feb; Vol. 54 (2), pp. 126-134. Date of Electronic Publication: 2019 Nov 10. |
| نوع المنشور: | Comparative Study; Journal Article; Multicenter Study; Observational Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sage Publications Country of Publication: United States NLM ID: 101136421 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-9116 (Electronic) Linking ISSN: 15385744 NLM ISO Abbreviation: Vasc Endovascular Surg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Thousand Oaks, CA : Sage Publications Original Publication: Glen Head, N.Y. : Westminster Publications, c2002- |
| مواضيع طبية MeSH: | Conservative Treatment*/adverse effects , Conservative Treatment*/mortality , Endovascular Procedures*/adverse effects , Endovascular Procedures*/mortality , Quality of Life* , Vascular Surgical Procedures*/adverse effects , Vascular Surgical Procedures*/mortality, Ischemia/*therapy , Peripheral Arterial Disease/*therapy, Age Factors ; Aged ; Aged, 80 and over ; Critical Illness ; Female ; Humans ; Ischemia/diagnostic imaging ; Ischemia/mortality ; Ischemia/physiopathology ; Male ; Netherlands ; Patient Selection ; Peripheral Arterial Disease/diagnostic imaging ; Peripheral Arterial Disease/mortality ; Peripheral Arterial Disease/physiopathology ; Prospective Studies ; Risk Factors ; Time Factors ; Treatment Outcome |
| مستخلص: | Introduction: Revascularization is the cornerstone of the treatment of critical limb ischemia (CLI), but the number of elderly frail patients increase. Revascularization is not always possible in these patients and conservative therapy seems to be an option. The goals of this study are to analyze the 1-year quality of life (QoL) results and mortality rates of elderly patients with CLI and to investigate if conservative treatment could be an acceptable treatment option. Methods: Patients with CLI ≥70 years old were included in a prospective observational cohort study in 2 hospitals in the Netherlands between 2012 and 2016 and were divided over 3 treatment modalities: endovascular therapy, surgical revascularization, and conservative treatment. The World Health Organization Quality of Life (WHOQoL-Bref) instrument, a generic QoL assessment tool that includes components of physical, psychological, social relationships and environment, was used to evaluate QoL at baseline, 6 months, and 1 year. Results: In total, 195 patients (56% male, 33% Rutherford 4, mean age of 80) were included. Physical QoL significantly increased after surgical (10.4 vs 14.9, P < .001), endovascular (10.9 vs 13.7, P < .001), and conservative therapy (11.6 vs 13.2, P = .01) at 1 year. One-year mortality was relatively low after surgery (10%) compared to endovascular (40%) and conservative therapy (37%). Conclusion: The results of this study could not be used to designate the superior treatment used in elderly patients with CLI. Conservative treatment could be an acceptable treatment option in selected patients with CLI unfit for revascularization. Treatment of choice in elderly patients with CLI is based on multiple factors and should be individualized in a shared decision-making process. |
| فهرسة مساهمة: | Keywords: conservative therapy; critical limb ischemia; elderly patients; quality of life |
| تواريخ الأحداث: | Date Created: 20191112 Date Completed: 20200115 Latest Revision: 20220412 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1177/1538574419885478 |
| PMID: | 31709914 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1938-9116 |
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| DOI: | 10.1177/1538574419885478 |