دورية أكاديمية
Predictive factor of recurrence after curative resection for stage I-II colon cancer.
| العنوان: | Predictive factor of recurrence after curative resection for stage I-II colon cancer. |
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| المؤلفون: | Dougaz W, Bouasker I, Gouta EL, Khalfallah M, Oueslati A, Samaali I, Ghariani W, Jerraya H, Nouira R, Dziri C |
| المصدر: | La Tunisie medicale [Tunis Med] 2019 May; Vol. 97 (5), pp. 685-691. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Societe Tunisienne Des Sciences Medicales Country of Publication: Tunisia NLM ID: 0413766 Publication Model: Print Cited Medium: Internet ISSN: 2724-7031 (Electronic) Linking ISSN: 00414131 NLM ISO Abbreviation: Tunis Med Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Tunis : Societe Tunisienne Des Sciences Medicales |
| مواضيع طبية MeSH: | Colonic Neoplasms/*epidemiology , Colonic Neoplasms/*surgery , Neoplasm Recurrence, Local/*epidemiology, Adult ; Aged ; Aged, 80 and over ; Cohort Studies ; Colonic Neoplasms/pathology ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Prognosis ; Retrospective Studies |
| مستخلص: | Background: Colon cancer has become a common malignant neoplasm in Tunisia. Patients with negative lymph node have a 5 years recurrence rate of 21.1%. Studies reporting the prognostic factors of recurrence for patients with stage I-II colon cancer are limited. Aim: This study aimed to determine factors predicting recurrence for patients with stage I-II colon cancer after curative resection. Methods: This was a retrospective cohort study. Were included patients who underwent curative surgery for stage I or II colon cancer. Enrolled variables were subdivided into: Pre-operative, Intraoperative and Post-operative variables. Main outcome measures were local recurrence and distant metastasis detected during follow-up. Results: Eighteen men and 17 women with median age of 61 years, ranging from 33 to 89, were enrolled in this study. Twenty-eight patients out of 35 were classified T3 and T4 colon cancer. The mean number of lymph nodes harvested was 16.23 (median= 17; range: 4-44). Ten patients (28%) had colloid component in the tumor. At a median follow-up of 23 months (range: 6-56 months), recurrence was observed in five cases (14%). Variables associated to recurrence were Carcinoembryonic antigen level (p= 0.03), serum albumin level (p=0.029) and the presence of colloid component (0.02). Multivariate logistic regression retained colloid component as the only predictive factor of recurrence (OR=1.2, 95%CI [1.019-1.412], p=0.028). Conclusions: This study showed that the percentage of mucinous component equal or greater than 25% was the only predictive factor of recurrence for curatively resected, stages I and II, colon cancer. |
| تواريخ الأحداث: | Date Created: 20191116 Date Completed: 20200430 Latest Revision: 20200430 |
| رمز التحديث: | 20240829 |
| PMID: | 31729741 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2724-7031 |
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