دورية أكاديمية
أعرض في EDS

Study of the epidemiological behavior of malaria in the Darien Region, Panama. 2015-2017.

التفاصيل البيبلوغرافية
العنوان: Study of the epidemiological behavior of malaria in the Darien Region, Panama. 2015-2017.
المؤلفون: Cáceres Carrera L; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama., Victoria C; Malaria Program, Ministry of Health, Panama City, Panama., Ramirez JL; Crop Bioprotection Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service, United States Department of Agriculture, Peoria, Illinois, United States of America., Jackman C; Epidemiology Department of the Darién Region, Ministry of Health, Panama City, Panama., Calzada JE; Direcction of Research and Technological Development, Gorgas Memorial Institute of Health Studies, Panama City, Panama., Torres R; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama.
المصدر: PloS one [PLoS One] 2019 Nov 15; Vol. 14 (11), pp. e0224508. Date of Electronic Publication: 2019 Nov 15 (Print Publication: 2019).
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Endemic Diseases/*statistics & numerical data , Malaria, Falciparum/*epidemiology , Malaria, Vivax/*epidemiology , Plasmodium falciparum/*isolation & purification , Plasmodium vivax/*isolation & purification, Adolescent ; Adult ; Aged ; Antimalarials/therapeutic use ; Child ; Child, Preschool ; Colombia ; Female ; Humans ; Incidence ; Infant ; Malaria, Falciparum/blood ; Malaria, Falciparum/drug therapy ; Malaria, Falciparum/parasitology ; Malaria, Vivax/blood ; Malaria, Vivax/drug therapy ; Malaria, Vivax/parasitology ; Male ; Middle Aged ; Panama/epidemiology ; Retrospective Studies ; Sex Factors ; Spatio-Temporal Analysis ; Travel-Related Illness ; Young Adult
مستخلص: Background: Malaria is endemic in Darién and an assessment of the different factors affecting its epidemiology is crucial for the development of adequate strategies of surveillance, prevention, and disease control. The objective of this study was to determine the main characteristics of the epidemiological behavior of malaria in the Darien region.
Methods: This research was comprised of a retrospective analysis to determine the incidence and malaria distribution in the Darien region from 2015 to 2017. We evaluated malaria indicators, disease distribution, incidence (by age group and sex), diagnostic methods, treatment, and control measures. In addition, we examined the cross-border migration activity and its possible contribution to the maintenance and distribution of malaria.
Results: During the period of 2015-2017, we examined 41,141 thick blood smear samples, out of which 501 tested positive for malaria. Plasmodium vivax was responsible for 92.2% of those infections. Males comprised 62.7% of the total diagnosed cases. Meanwhile, a similar percentage, 62.7%, of the total cases were registered in economically active ages. The more frequent symptoms included fever (99.4%) and chills (97.4%), with 53.1% of cases registering between 2,000 and 6,000 parasites/μl of blood. The annual parasitic incidence (API) average was 3.0/1,000 inhabitants, while the slide positivity rate (SPR) was 1.2% and the annual blood examination rate (ABER) 22.5%. In Darién there is a constant internal and cross-border migration movement between Panama and Colombia. Malaria control measures consisted of the active and passive search of suspected cases and of the application of vector control measures.
Conclusion: This study provides an additional perspective on malaria epidemiology in Darién. Additional efforts are required to intensify malaria surveillance and to achieve an effective control, eventually moving closer to the objective of malaria elimination. At the same time, there is a need for more eco-epidemiological, entomological and migratory studies to determine how these factors contribute to the patterns of maintenance and dissemination of malaria.
Competing Interests: The authors have declared that no competing interests exist. LC is member of the Sistema Nacional de Investigación (SNI), SENACYT, Panama. Any opinions, findings, conclusions or recommendations expressed in this publication are those of the author(s) and do not necessarily reflect the view of the U.S. Department of Agriculture. The mention of firm names or trade products does not imply that they are endorsed or recommended by the U.S. Department of Agriculture over other firms or similar products not mentioned; the USDA is an equal opportunity employer.
References: Am J Trop Med Hyg. 2001 Jan-Feb;64(1-2 Suppl):97-106. (PMID: 11425182)
Adv Parasitol. 2012;80:203-70. (PMID: 23199489)
Emerg Microbes Infect. 2014 Apr;3(4):e27. (PMID: 26038518)
Malar J. 2016 Nov 11;15(1):551. (PMID: 27835976)
Malar J. 2018 Feb 20;17(1):85. (PMID: 29463259)
Biomedica. 2012 Oct-Dec;32(4):557-69. (PMID: 23715231)
PLoS Negl Trop Dis. 2014 Aug 14;8(8):e3071. (PMID: 25121491)
Lancet. 2003 Nov 29;362(9398):1792-8. (PMID: 14654317)
Rev Soc Bras Med Trop. 2010 Jan-Feb;43(1):52-8. (PMID: 20305969)
Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2452-7. (PMID: 16461902)
Malar J. 2014 Mar 14;13:97. (PMID: 24629066)
BMJ. 2007 Mar 10;334(7592):489. (PMID: 17347193)
Lancet. 2002 Aug 24;360(9333):610-7. (PMID: 12241933)
Trop Med Int Health. 2015 Jun;20(6):773-80. (PMID: 25689689)
Clin Exp Immunol. 2003 Aug;133(2):145-52. (PMID: 12869017)
Rev Soc Bras Med Trop. 2008 Jul-Aug;41(4):386-9. (PMID: 18853012)
Emerg Infect Dis. 2007 Jul;13(7):1125-6. (PMID: 18214203)
Cien Saude Colet. 2012 Sep;17(9):2415-24. (PMID: 22996892)
Am J Trop Med Hyg. 2009 Jun;80(6):882-8. (PMID: 19478243)
Lancet. 1992 Mar 14;339(8794):690; author reply 690-1. (PMID: 1347393)
Biomedica. 2011 Jul-Sep;31(3):419-27. (PMID: 22674318)
Parasitol Today. 1994 Nov;10(11):439-42. (PMID: 15275531)
Int J Epidemiol. 1977 Sep;6(3):259-67. (PMID: 591173)
Antimicrob Agents Chemother. 2016 Jul 22;60(8):4610-9. (PMID: 27185794)
Mem Inst Oswaldo Cruz. 2011 Aug;106 Suppl 1:114-22. (PMID: 21881765)
Bull World Health Organ. 1973 May;48(5):591-6. (PMID: 4130021)
Biomedica. 2006 Jun;26(2):278-85. (PMID: 16925100)
Cochrane Database Syst Rev. 2013 Oct 26;(10):CD004389. (PMID: 24163057)
Soc Sci Med. 1993 Nov;37(9):1155-67. (PMID: 8235755)
Malar J. 2016 Nov 28;15(1):573. (PMID: 27894320)
Lancet Infect Dis. 2010 Jun;10(6):405-16. (PMID: 20510281)
East Afr Med J. 1968 May;45(5):266-75. (PMID: 5674005)
Parasitol Today. 1998 May;14(5):177-8. (PMID: 17040744)
Am J Trop Med Hyg. 2006 May;74(5):772-8. (PMID: 16687679)
Trans R Soc Trop Med Hyg. 2000 Apr;94 Suppl 1:S1-90. (PMID: 11103309)
PLoS One. 2013;8(1):e55777. (PMID: 23383280)
Am J Trop Med Hyg. 1999 Jul;61(1 Suppl):36-43. (PMID: 10432043)
Am J Trop Med Hyg. 1994 Jul;51(1):16-25. (PMID: 8059911)
PLoS Negl Trop Dis. 2016 May 16;10(5):e0004718. (PMID: 27182773)
N Engl J Med. 2009 Jul 30;361(5):455-67. (PMID: 19641202)
Nature. 2010 May 20;465(7296):342-5. (PMID: 20485434)
Bull World Health Organ. 1995;73(5):565-71. (PMID: 8846482)
J Parasitol. 2002 Jun;88(3):521-35. (PMID: 12099421)
Malar J. 2015 Nov 17;14:459. (PMID: 26578076)
Malar J. 2015 Oct 15;14:408. (PMID: 26466889)
PLoS Med. 2009 Mar 24;6(3):e1000048. (PMID: 19323591)
Hist Cienc Saude Manguinhos. 2013 Jun;20(2):391-410. (PMID: 23903910)
PLoS Med. 2011 Jan 25;8(1):e1000412. (PMID: 21311585)
Am J Trop Med Hyg. 2005 Nov;73(5):839-41. (PMID: 16282290)
Parasitol Today. 1987 Jun;3(6):166-70. (PMID: 15462945)
Malar J. 2014 May 03;13:169. (PMID: 24886389)
Parasitol Today. 1999 Mar;15(3):105-11. (PMID: 10322323)
Lancet Infect Dis. 2008 Jun;8(6):387-9. (PMID: 18374633)
Adv Parasitol. 2012;80:113-50. (PMID: 23199487)
Biomedica. 2017 Mar 29;37(0):98-105. (PMID: 29161482)
Trends Parasitol. 2014 Apr;30(4):183-90. (PMID: 24642035)
Proc Biol Sci. 2005 Jun 7;272(1568):1153-61. (PMID: 16024377)
Ann N Y Acad Sci. 2015 Apr;1342:62-7. (PMID: 25891142)
Am J Trop Med Hyg. 2015 Sep;93(3 Suppl):79-86. (PMID: 26259945)
Malar J. 2011 Apr 09;10:80. (PMID: 21477321)
Nature. 2015 Dec 3;528(7580):S94-101. (PMID: 26633771)
Parasit Vectors. 2017 Apr 20;10(1):198. (PMID: 28427447)
J Parasitol. 2002 Apr;88(2):295-8. (PMID: 12054000)
J Med Entomol. 2008 Sep;45(5):841-51. (PMID: 18826025)
Malar J. 2010 Apr 21;9:105. (PMID: 20409302)
Science. 2000 Sep 8;289(5485):1763-6. (PMID: 10976072)
Antimicrob Agents Chemother. 2014;58(1):342-7. (PMID: 24165179)
Biomedica. 2015 Dec 07;36(0):98-107. (PMID: 27622797)
Am J Trop Med Hyg. 2016 Dec 28;95(6 Suppl):35-51. (PMID: 27708191)
Trans R Soc Trop Med Hyg. 2000 Jul-Aug;94(4):367-71. (PMID: 11127234)
Am J Trop Med Hyg. 2009 Jul;81(1):23-6. (PMID: 19556561)
Malar J. 2008 Oct 27;7:218. (PMID: 18954430)
Malar J. 2013 Feb 07;12:56. (PMID: 23388506)
Trop Med Int Health. 2016 May;21(5):675-86. (PMID: 26914617)
Trends Parasitol. 2004 Apr;20(4):192-8. (PMID: 15099559)
PLoS One. 2019 Feb 6;14(2):e0211258. (PMID: 30726279)
Am J Trop Med Hyg. 1996 Jul;55(1):32-8. (PMID: 8702019)
المشرفين على المادة: 0 (Antimalarials)
تواريخ الأحداث: Date Created: 20191116 Date Completed: 20200402 Latest Revision: 20200402
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC6857920
DOI: 10.1371/journal.pone.0224508
PMID: 31730618
قاعدة البيانات: MEDLINE
الوصف
تدمد:1932-6203
DOI:10.1371/journal.pone.0224508