دورية أكاديمية
Study of the epidemiological behavior of malaria in the Darien Region, Panama. 2015-2017.
العنوان: | Study of the epidemiological behavior of malaria in the Darien Region, Panama. 2015-2017. |
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المؤلفون: | Cáceres Carrera L; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama., Victoria C; Malaria Program, Ministry of Health, Panama City, Panama., Ramirez JL; Crop Bioprotection Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service, United States Department of Agriculture, Peoria, Illinois, United States of America., Jackman C; Epidemiology Department of the Darién Region, Ministry of Health, Panama City, Panama., Calzada JE; Direcction of Research and Technological Development, Gorgas Memorial Institute of Health Studies, Panama City, Panama., Torres R; Department of Medical Entomology, Gorgas Memorial Institute of Health Studies, Panama City, Panama. |
المصدر: | PloS one [PLoS One] 2019 Nov 15; Vol. 14 (11), pp. e0224508. Date of Electronic Publication: 2019 Nov 15 (Print Publication: 2019). |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: San Francisco, CA : Public Library of Science |
مواضيع طبية MeSH: | Endemic Diseases/*statistics & numerical data , Malaria, Falciparum/*epidemiology , Malaria, Vivax/*epidemiology , Plasmodium falciparum/*isolation & purification , Plasmodium vivax/*isolation & purification, Adolescent ; Adult ; Aged ; Antimalarials/therapeutic use ; Child ; Child, Preschool ; Colombia ; Female ; Humans ; Incidence ; Infant ; Malaria, Falciparum/blood ; Malaria, Falciparum/drug therapy ; Malaria, Falciparum/parasitology ; Malaria, Vivax/blood ; Malaria, Vivax/drug therapy ; Malaria, Vivax/parasitology ; Male ; Middle Aged ; Panama/epidemiology ; Retrospective Studies ; Sex Factors ; Spatio-Temporal Analysis ; Travel-Related Illness ; Young Adult |
مستخلص: | Background: Malaria is endemic in Darién and an assessment of the different factors affecting its epidemiology is crucial for the development of adequate strategies of surveillance, prevention, and disease control. The objective of this study was to determine the main characteristics of the epidemiological behavior of malaria in the Darien region. Methods: This research was comprised of a retrospective analysis to determine the incidence and malaria distribution in the Darien region from 2015 to 2017. We evaluated malaria indicators, disease distribution, incidence (by age group and sex), diagnostic methods, treatment, and control measures. In addition, we examined the cross-border migration activity and its possible contribution to the maintenance and distribution of malaria. Results: During the period of 2015-2017, we examined 41,141 thick blood smear samples, out of which 501 tested positive for malaria. Plasmodium vivax was responsible for 92.2% of those infections. Males comprised 62.7% of the total diagnosed cases. Meanwhile, a similar percentage, 62.7%, of the total cases were registered in economically active ages. The more frequent symptoms included fever (99.4%) and chills (97.4%), with 53.1% of cases registering between 2,000 and 6,000 parasites/μl of blood. The annual parasitic incidence (API) average was 3.0/1,000 inhabitants, while the slide positivity rate (SPR) was 1.2% and the annual blood examination rate (ABER) 22.5%. In Darién there is a constant internal and cross-border migration movement between Panama and Colombia. Malaria control measures consisted of the active and passive search of suspected cases and of the application of vector control measures. Conclusion: This study provides an additional perspective on malaria epidemiology in Darién. Additional efforts are required to intensify malaria surveillance and to achieve an effective control, eventually moving closer to the objective of malaria elimination. At the same time, there is a need for more eco-epidemiological, entomological and migratory studies to determine how these factors contribute to the patterns of maintenance and dissemination of malaria. Competing Interests: The authors have declared that no competing interests exist. LC is member of the Sistema Nacional de Investigación (SNI), SENACYT, Panama. Any opinions, findings, conclusions or recommendations expressed in this publication are those of the author(s) and do not necessarily reflect the view of the U.S. Department of Agriculture. The mention of firm names or trade products does not imply that they are endorsed or recommended by the U.S. Department of Agriculture over other firms or similar products not mentioned; the USDA is an equal opportunity employer. |
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المشرفين على المادة: | 0 (Antimalarials) |
تواريخ الأحداث: | Date Created: 20191116 Date Completed: 20200402 Latest Revision: 20200402 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC6857920 |
DOI: | 10.1371/journal.pone.0224508 |
PMID: | 31730618 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1932-6203 |
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DOI: | 10.1371/journal.pone.0224508 |