دورية أكاديمية
أعرض في EDS

Anticoagulant Reversal Strategies in the Emergency Department Setting: Recommendations of a Multidisciplinary Expert Panel.

التفاصيل البيبلوغرافية
العنوان: Anticoagulant Reversal Strategies in the Emergency Department Setting: Recommendations of a Multidisciplinary Expert Panel.
المؤلفون: Baugh CW; Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA. Electronic address: cbaugh@bwh.harvard.edu., Levine M; Department of Emergency Medicine, Keck School of Medicine at the University of Southern California, Los Angeles, CA., Cornutt D; Department of Emergency Medicine, Regional West Health Systems, Scottsbluff, NE., Wilson JW; Department of Emergency Medicine, Tampa General Hospital, Tampa, FL., Kwun R; Department of Emergency Medicine, Swedish/Mill Creek, Everett, WA., Mahan CE; Presbyterian Healthcare Services, University of New Mexico College of Pharmacy, Albuquerque, NM., Pollack CV Jr; Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA., Marcolini EG; Department of Medicine, Section of Emergency Medicine, Geisel School of Medicine at Dartmouth, Hanover, NH., Milling TJ Jr; Seton Dell Medical School Stroke Institute, Austin, TX., Peacock WF; Department of Emergency Medicine, Baylor College of Medicine, Houston, TX., Rosovsky RP; Department of Hematology/Oncology, Massachusetts General Hospital, Boston, MA., Wu F; Department of Emergency Medicine, University of California San Francisco-Fresno, Fresno, CA., Sarode R; Department of Pathology and Internal Medicine (Hematology/Oncology), University of Texas Southwestern Medical Center, Dallas, TX., Spyropoulos AC; Department of Medicine, Northwell Health, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY., Villines TC; Department of Medicine, University of Virginia Health System, Charlottesville, VA., Woods TD; Department of Surgery, Cox Medical Center, Springfield, MO., McManus J; Department of Emergency Medicine, Augusta University, Augusta, GA., Williams J; Department of Emergency Medicine, Covenant Medical Center, Lubbock, TX. Electronic address: williamsja@usacs.com.
المصدر: Annals of emergency medicine [Ann Emerg Med] 2020 Oct; Vol. 76 (4), pp. 470-485. Date of Electronic Publication: 2019 Nov 13.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 8002646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6760 (Electronic) Linking ISSN: 01960644 NLM ISO Abbreviation: Ann Emerg Med Subsets: MEDLINE
أسماء مطبوعة: Publication: St. Louis, MO : Mosby
Original Publication: [Lansing, Mich., American College of Emergency Physicians]
مواضيع طبية MeSH: Drug Antagonism*, Anticoagulants/*administration & dosage, Anticoagulants/therapeutic use ; Consensus ; Emergency Service, Hospital/organization & administration ; Emergency Service, Hospital/statistics & numerical data ; Expert Testimony ; Hemorrhage/drug therapy ; Humans
مستخلص: Bleeding is the most common complication of anticoagulant use. The evaluation and management of the bleeding patient is a core competency of emergency medicine. As the prevalence of patients receiving anticoagulant agents and variety of anticoagulants with different mechanisms of action, pharmacokinetics, indications, and corresponding reversal agents increase, physicians and other clinicians working in the emergency department require a current and nuanced understanding of how best to assess, treat, and reverse anticoagulated patients. In this project, we convened an expert panel to create a consensus decision tree and framework for assessment of the bleeding patient receiving an anticoagulant, as well as use of anticoagulant reversal or coagulation factor replacement, and to address controversies and gaps relevant to this topic. To support decision tree interpretation, the panel also reached agreement on key definitions of life-threatening bleeding, bleeding at a critical site, and emergency surgery or urgent invasive procedure. To reach consensus recommendations, we used a structured literature review and a modified Delphi technique by an expert panel of academic and community physicians with training in emergency medicine, cardiology, hematology, internal medicine/thrombology, pharmacology, toxicology, transfusion medicine and hemostasis, neurology, and surgery, and by other key stakeholder groups.
(Copyright © 2019 American College of Emergency Physicians. Published by Elsevier Inc. All rights reserved.)
التعليقات: Comment in: Ann Emerg Med. 2020 Oct;76(4):486-488. (PMID: 32653330)
References: Am J Emerg Med. 2019 Feb;37(2):374.e3-374.e4. (PMID: 30409461)
N Engl J Med. 2013 Feb 21;368(8):699-708. (PMID: 23216615)
Circulation. 2006 Aug 22;114(8):774-82. (PMID: 16908769)
Pharmacology. 2018;101(1-2):92-95. (PMID: 29131074)
N Engl J Med. 2011 Sep 15;365(11):981-92. (PMID: 21870978)
BMC Pregnancy Childbirth. 2018 Jun 7;18(1):215. (PMID: 29879947)
Lancet. 2016 Jun 25;387(10038):2605-2613. (PMID: 27178479)
N Engl J Med. 2017 Oct 5;377(14):1319-1330. (PMID: 28844192)
JAMA. 2016 Nov 22;316(20):2115-2125. (PMID: 27893129)
Thromb Res. 2012 Dec;130(6):833-40. (PMID: 23137921)
Blood. 2017 Oct 12;130(15):1706-1712. (PMID: 28835439)
Chest. 2016 Feb;149(2):315-352. (PMID: 26867832)
PLoS Med. 2009 Jul 21;6(7):e1000097. (PMID: 19621072)
Am J Ther. 2018 May/Jun;25(3):e326-e332. (PMID: 28763307)
Acad Emerg Med. 2015 Jul;22(7):856-64. (PMID: 26112797)
J Thromb Thrombolysis. 2016 Feb;41(2):248-52. (PMID: 26449414)
Br J Surg. 2017 May;104(6):710-717. (PMID: 28230248)
Circulation. 2016 Jan 26;133(4):e38-360. (PMID: 26673558)
Thromb J. 2015 Oct 05;13:33. (PMID: 26500456)
Circulation. 2005 Apr 26;111(16):2042-9. (PMID: 15824203)
Lancet. 2015 May 23;385(9982):2077-87. (PMID: 25728933)
N Engl J Med. 2019 Feb 21;380(8):720-728. (PMID: 30786186)
Cochrane Database Syst Rev. 2015 Jul 07;(7):CD010555. (PMID: 26151108)
J Thromb Haemost. 2016 Jan;14(1):211-4. (PMID: 26391431)
J Thromb Thrombolysis. 2015 Apr;39(3):295-303. (PMID: 25605686)
Crit Care. 2011;15(1):201. (PMID: 21345266)
J Thromb Thrombolysis. 2010 Nov;30(4):434-40. (PMID: 20213257)
Clin Otolaryngol. 2016 Dec;41(6):771-776. (PMID: 26946067)
Pharmacotherapy. 2018 Sep;38(9):907-920. (PMID: 29920705)
Eur Heart J. 2003 Oct;24(20):1815-23. (PMID: 14563340)
N Engl J Med. 2019 Apr 4;380(14):1326-1335. (PMID: 30730782)
PLoS One. 2018 Jun 7;13(6):e0198674. (PMID: 29879194)
J Am Coll Cardiol. 2017 Dec 19;70(24):3042-3067. (PMID: 29203195)
Circulation. 2009 Jan 27;119(3):e21-181. (PMID: 19075105)
J Am Coll Cardiol. 2019 Jan 22;73(2):121-130. (PMID: 30654882)
Vox Sang. 2016 Jul;111(1):55-61. (PMID: 26919686)
J Thromb Haemost. 2018 Jan;16(1):54-64. (PMID: 29106076)
Clin Pharmacokinet. 2017 Jul;56(7):793-801. (PMID: 27910037)
Ann Emerg Med. 2019 May;73(5):545-547. (PMID: 31029291)
N Engl J Med. 2017 Mar 30;376(13):1211-1222. (PMID: 28316279)
Stroke. 2019 Apr;50(4):939-946. (PMID: 30869568)
Thromb Haemost. 2018 May;118(5):842-851. (PMID: 29564837)
N Engl J Med. 2016 Sep 22;375(12):1131-41. (PMID: 27573206)
Eur Heart J. 2012 Nov;33(21):2719-47. (PMID: 22922413)
N Engl J Med. 2011 Sep 8;365(10):883-91. (PMID: 21830957)
Acad Emerg Med. 2016 Dec;23(12):1313-1319. (PMID: 27396583)
Lancet. 2018 Jan 20;391(10117):219-229. (PMID: 29132880)
Circulation. 2011 Jun 14;123(23):2736-47. (PMID: 21670242)
N Engl J Med. 2017 Aug 3;377(5):431-441. (PMID: 28693366)
J Thromb Haemost. 2015 Nov;13(11):2119-26. (PMID: 26764429)
Circulation. 2019 Jul 9;140(2):e125-e151. (PMID: 30686041)
Lancet. 2010 Jan 16;375(9710):201-9. (PMID: 20060578)
N Engl J Med. 2009 Sep 17;361(12):1139-51. (PMID: 19717844)
Thromb Res. 2019 Jan;173:71-76. (PMID: 30476716)
Ann Emerg Med. 2019 Mar;73(3):269-271. (PMID: 30292524)
Int J Clin Pharm. 2016 Jun;38(3):655-62. (PMID: 26846316)
J Thromb Thrombolysis. 2016 Jan;41(1):3-14. (PMID: 26780736)
J Thromb Haemost. 2005 Apr;3(4):692-4. (PMID: 15842354)
Am J Ther. 2016 Nov/Dec;23(6):e1619-e1622. (PMID: 26241703)
Am J Cardiol. 2005 Nov 1;96(9):1200-6. (PMID: 16253582)
N Engl J Med. 2018 Sep 20;379(12):1118-1127. (PMID: 30145946)
معلومات مُعتمدة: K23 HL127227 United States HL NHLBI NIH HHS
المشرفين على المادة: 0 (Anticoagulants)
تواريخ الأحداث: Date Created: 20191117 Date Completed: 20201109 Latest Revision: 20210110
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC7393606
DOI: 10.1016/j.annemergmed.2019.09.001
PMID: 31732375
قاعدة البيانات: MEDLINE
الوصف
تدمد:1097-6760
DOI:10.1016/j.annemergmed.2019.09.001