دورية أكاديمية
Anticoagulant Reversal Strategies in the Emergency Department Setting: Recommendations of a Multidisciplinary Expert Panel.
العنوان: | Anticoagulant Reversal Strategies in the Emergency Department Setting: Recommendations of a Multidisciplinary Expert Panel. |
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المؤلفون: | Baugh CW; Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA. Electronic address: cbaugh@bwh.harvard.edu., Levine M; Department of Emergency Medicine, Keck School of Medicine at the University of Southern California, Los Angeles, CA., Cornutt D; Department of Emergency Medicine, Regional West Health Systems, Scottsbluff, NE., Wilson JW; Department of Emergency Medicine, Tampa General Hospital, Tampa, FL., Kwun R; Department of Emergency Medicine, Swedish/Mill Creek, Everett, WA., Mahan CE; Presbyterian Healthcare Services, University of New Mexico College of Pharmacy, Albuquerque, NM., Pollack CV Jr; Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA., Marcolini EG; Department of Medicine, Section of Emergency Medicine, Geisel School of Medicine at Dartmouth, Hanover, NH., Milling TJ Jr; Seton Dell Medical School Stroke Institute, Austin, TX., Peacock WF; Department of Emergency Medicine, Baylor College of Medicine, Houston, TX., Rosovsky RP; Department of Hematology/Oncology, Massachusetts General Hospital, Boston, MA., Wu F; Department of Emergency Medicine, University of California San Francisco-Fresno, Fresno, CA., Sarode R; Department of Pathology and Internal Medicine (Hematology/Oncology), University of Texas Southwestern Medical Center, Dallas, TX., Spyropoulos AC; Department of Medicine, Northwell Health, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY., Villines TC; Department of Medicine, University of Virginia Health System, Charlottesville, VA., Woods TD; Department of Surgery, Cox Medical Center, Springfield, MO., McManus J; Department of Emergency Medicine, Augusta University, Augusta, GA., Williams J; Department of Emergency Medicine, Covenant Medical Center, Lubbock, TX. Electronic address: williamsja@usacs.com. |
المصدر: | Annals of emergency medicine [Ann Emerg Med] 2020 Oct; Vol. 76 (4), pp. 470-485. Date of Electronic Publication: 2019 Nov 13. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Mosby Country of Publication: United States NLM ID: 8002646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6760 (Electronic) Linking ISSN: 01960644 NLM ISO Abbreviation: Ann Emerg Med Subsets: MEDLINE |
أسماء مطبوعة: | Publication: St. Louis, MO : Mosby Original Publication: [Lansing, Mich., American College of Emergency Physicians] |
مواضيع طبية MeSH: | Drug Antagonism*, Anticoagulants/*administration & dosage, Anticoagulants/therapeutic use ; Consensus ; Emergency Service, Hospital/organization & administration ; Emergency Service, Hospital/statistics & numerical data ; Expert Testimony ; Hemorrhage/drug therapy ; Humans |
مستخلص: | Bleeding is the most common complication of anticoagulant use. The evaluation and management of the bleeding patient is a core competency of emergency medicine. As the prevalence of patients receiving anticoagulant agents and variety of anticoagulants with different mechanisms of action, pharmacokinetics, indications, and corresponding reversal agents increase, physicians and other clinicians working in the emergency department require a current and nuanced understanding of how best to assess, treat, and reverse anticoagulated patients. In this project, we convened an expert panel to create a consensus decision tree and framework for assessment of the bleeding patient receiving an anticoagulant, as well as use of anticoagulant reversal or coagulation factor replacement, and to address controversies and gaps relevant to this topic. To support decision tree interpretation, the panel also reached agreement on key definitions of life-threatening bleeding, bleeding at a critical site, and emergency surgery or urgent invasive procedure. To reach consensus recommendations, we used a structured literature review and a modified Delphi technique by an expert panel of academic and community physicians with training in emergency medicine, cardiology, hematology, internal medicine/thrombology, pharmacology, toxicology, transfusion medicine and hemostasis, neurology, and surgery, and by other key stakeholder groups. (Copyright © 2019 American College of Emergency Physicians. Published by Elsevier Inc. All rights reserved.) |
التعليقات: | Comment in: Ann Emerg Med. 2020 Oct;76(4):486-488. (PMID: 32653330) |
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معلومات مُعتمدة: | K23 HL127227 United States HL NHLBI NIH HHS |
المشرفين على المادة: | 0 (Anticoagulants) |
تواريخ الأحداث: | Date Created: 20191117 Date Completed: 20201109 Latest Revision: 20210110 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC7393606 |
DOI: | 10.1016/j.annemergmed.2019.09.001 |
PMID: | 31732375 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1097-6760 |
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DOI: | 10.1016/j.annemergmed.2019.09.001 |