دورية أكاديمية
أعرض في EDS

Nutritional Status and Cognitive Impairment among the Very Old in a Community Sample from Southern Brazil.

التفاصيل البيبلوغرافية
العنوان: Nutritional Status and Cognitive Impairment among the Very Old in a Community Sample from Southern Brazil.
المؤلفون: Senger J; João Senger, MD, MSc, Avenida Unisinos, 950, 93022750 - São Leopoldo, RS, Brazil, Phone: +55 (51) 3591-1122, jjej@sinos.net., Bruscato NM, Werle B, Moriguchi EH, Pattussi MP
المصدر: The journal of nutrition, health & aging [J Nutr Health Aging] 2019; Vol. 23 (10), pp. 923-929.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Masson SAS on behalf of SERDI Publisher Country of Publication: France NLM ID: 100893366 Publication Model: Print Cited Medium: Internet ISSN: 1760-4788 (Electronic) Linking ISSN: 12797707 NLM ISO Abbreviation: J Nutr Health Aging Subsets: MEDLINE
أسماء مطبوعة: Publication: 2024- : [Paris, France] : Elsevier Masson SAS on behalf of SERDI Publisher
Original Publication: Paris, France : New York, NY : Serdi Publisher ; Springer Pub. Co.,
مواضيع طبية MeSH: Nutrition Assessment*, Cognitive Dysfunction/*etiology , Nutritional Status/*physiology, Aged, 80 and over ; Brazil ; Cross-Sectional Studies ; Female ; Humans ; Male ; Prevalence
مستخلص: Objective: To determine which factors, especially those related to nutrition, are associated with cognitive function in the oldest old, here considered those at least 80 years of age.
Design: A cross-sectional, population-based study.
Setting: Veranópolis, Rio Grande do Sul, Brazil, and surrounding rural areas.
Participants: Individuals aged 80 years and older.
Measurements: The Mini Nutritional Assessment, anthropometric measurements, and serum levels of albumin and vitamin B12 were associated with cognitive function according to the Mini Mental State Examination (MMSE) and the Clock Drawing Test (CDT). Socio-demographic data were obtained through a structured questionnaire. Multivariate analysis was used to determine the associations.
Results: According to the MMSE and the CDT, the prevalence of cognitive impairment was 47.7% [95%CI 39.7-55.7] and 58.2% [95%CI 50.3-66.1], respectively. In the adjusted analysis, the only positive linear association with MMSE scores indicating cognitive impairment was age. However, CDT scores indicating cognitive impairment were five times higher among those with low serum vitamin B12 concentrations. For the other variables, there was a positive association between age, being widowed, a low educational level and central nervous system drugs. Being single, living with children and living alone were protective factors for cognitive impairment.
Conclusions: Although cognitive impairment was positively associated with old age, being widowed and low educational level in this population, the only nutritional variable positively associated with cognitive impairment was a low vitamin B12 concentration.
Competing Interests: The authors have no conflicts of interest to disclose
References: J Psychiatr Res. 1975 Nov;12(3):189-98. (PMID: 1202204)
Acta Neuropathol. 1991;82(4):239-59. (PMID: 1759558)
J Nutr Health Aging. 2006 Nov-Dec;10(6):456-63; discussion 463-5. (PMID: 17183418)
J Gerontol. 1993 Jul;48(4):M146-51. (PMID: 8315227)
Nutrients. 2018 Nov 09;10(11):. (PMID: 30423916)
J Am Geriatr Soc. 2012 Aug;60(8):1457-64. (PMID: 22788704)
Eur J Neurol. 1999 Nov;6(6):645-52. (PMID: 10529751)
Rev Saude Publica. 2002 Dec;36(6):773-8. (PMID: 12488947)
JAMA. 2013 Nov 27;310(20):2191-4. (PMID: 24141714)
Aging Clin Exp Res. 2010 Jun;22(3):192-7. (PMID: 19940557)
Arq Neuropsiquiatr. 1994 Mar;52(1):1-7. (PMID: 8002795)
Curr Opin Clin Nutr Metab Care. 2009 Jan;12(1):15-21. (PMID: 19057182)
J Nutr Health Aging. 2019;23(2):217-220. (PMID: 30697634)
Kidney Int. 2002 Jun;61(6):2240-9. (PMID: 12028466)
Int J Geriatr Psychiatry. 2000 Jun;15(6):548-61. (PMID: 10861923)
J Nutr Health Aging. 2013 Sep;17(9):738-9. (PMID: 24154644)
Arch Gerontol Geriatr. 2014 Nov-Dec;59(3):624-9. (PMID: 25183439)
Clin Geriatr Med. 2002 Nov;18(4):737-57. (PMID: 12608501)
Int J Obes (Lond). 2015 Sep;39(9):1383-9. (PMID: 25953125)
J Neuropsychiatry Clin Neurosci. 2000 Summer;12(3):389-94. (PMID: 10956574)
JAMA Psychiatry. 2016 Jun 1;73(6):606-13. (PMID: 27120188)
Proc Nutr Soc. 2019 May;78(2):221-233. (PMID: 30696516)
Neurol India. 2004 Sep;52(3):310-8. (PMID: 15472418)
Eur J Clin Nutr. 1999 Dec;53(12):905-14. (PMID: 10602346)
Alzheimer Dis Assoc Disord. 2002 Apr-Jun;16(2):103-8. (PMID: 12040305)
Am J Clin Nutr. 2009 Feb;89(2):693S-6S. (PMID: 19116323)
Am Fam Physician. 2011 Jun 15;83(12):1425-30. (PMID: 21671542)
Rev Bras Enferm. 2013 May-Jun;66(3):351-7. (PMID: 23887783)
Lancet. 2011 Mar 19;377(9770):1019-31. (PMID: 21371747)
QJM. 1995 May;88(5):357-64. (PMID: 7796091)
J Am Geriatr Soc. 2010 Feb;58(2):234-41. (PMID: 20370857)
Nutr Hosp. 2012 Mar-Apr;27(2):590-8. (PMID: 22732988)
Obes Rev. 2011 May;12(5):e426-37. (PMID: 21348917)
Arq Neuropsiquiatr. 2003 Sep;61(3B):777-81. (PMID: 14595482)
Psychol Sci Public Interest. 2008 Oct;9(1):1-65. (PMID: 26162004)
فهرسة مساهمة: Keywords: Cognitive aging; nutritional status; older adults; vitamin B12
تواريخ الأحداث: Date Created: 20191130 Date Completed: 20200623 Latest Revision: 20240317
رمز التحديث: 20240317
DOI: 10.1007/s12603-019-1230-x
PMID: 31781720
قاعدة البيانات: MEDLINE
الوصف
تدمد:1760-4788
DOI:10.1007/s12603-019-1230-x