دورية أكاديمية
أعرض في EDS

Prognostic value of the preoperative neutrophil-lymphocyte ratio in patients undergoing the bidirectional Glenn procedure.

التفاصيل البيبلوغرافية
العنوان: Prognostic value of the preoperative neutrophil-lymphocyte ratio in patients undergoing the bidirectional Glenn procedure.
المؤلفون: Manuel V; Division of Cardiovascular Surgery, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Pinheiros, São Paulo, Brazil.; Cardio-Thoracic Center, Clínica Girassol, Luanda, Angola., Miana LA; Division of Cardiovascular Surgery, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Pinheiros, São Paulo, Brazil., Guerreiro GP; Division of Cardiovascular Surgery, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Pinheiros, São Paulo, Brazil., Tenório DF; Division of Cardiovascular Surgery, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Pinheiros, São Paulo, Brazil., Turquetto A; Division of Cardiovascular Surgery, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Pinheiros, São Paulo, Brazil., Penha JG; Division of Cardiovascular Surgery, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Pinheiros, São Paulo, Brazil., Massoti MR; Division of Cardiovascular Surgery, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Pinheiros, São Paulo, Brazil., Tanamati C; Division of Cardiovascular Surgery, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Pinheiros, São Paulo, Brazil., Junior APF; Cardio-Thoracic Center, Clínica Girassol, Luanda, Angola., Caneo LF; Division of Cardiovascular Surgery, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Pinheiros, São Paulo, Brazil., Jatene FB; Division of Cardiovascular Surgery, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Pinheiros, São Paulo, Brazil., Jatene MB; Division of Cardiovascular Surgery, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Pinheiros, São Paulo, Brazil.
المصدر: Journal of cardiac surgery [J Card Surg] 2020 Feb; Vol. 35 (2), pp. 328-334. Date of Electronic Publication: 2019 Nov 29.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8908809 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-8191 (Electronic) Linking ISSN: 08860440 NLM ISO Abbreviation: J Card Surg Subsets: MEDLINE
أسماء مطبوعة: Publication: Hoboken, NJ : Wiley-Blackwell
Original Publication: Mount Kisco, N.Y. : Futura Pub. Co., Inc., [c1986-
مواضيع طبية MeSH: Leukocyte Count* , Lymphocyte Count* , Neutrophils*, Cardiac Surgical Procedures/*methods , Heart Defects, Congenital/*surgery , Heart Ventricles/*abnormalities , Heart Ventricles/*surgery, Adult ; Aged ; Cohort Studies ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Postoperative Complications/epidemiology ; Preoperative Period ; Prognosis ; Respiration, Artificial ; Retrospective Studies ; Time Factors
مستخلص: Introduction: The neutrophil-lymphocyte ratio (NLR) has been associated with worse outcomes in patients undergoing coronary artery bypass graft surgery. Little is known about this association in the pediatric population who require surgery for congenital heart defects, especially in patients with a single ventricle (SV).
Objective: To analyze the association of the preoperative NLR with outcomes in patients undergoing the bidirectional Glenn procedure.
Methods: This study involved a retrospective cohort analysis of 141 consecutive patients with SV undergoing the bidirectional Glenn procedure between January 2011 and December 2017 in two centers. The preoperative NLR was included in the last hemogram test before surgery. According to the NLR level, the patients were divided into group I (NLR < 1), group II (NLR between 1 and 2), and group III (NLR > 2). The primary endpoint was total hospital length of stay (LOS), and secondary endpoints were mechanical ventilation (MV) time, intensive care unit (ICU) LOS, ventricular dysfunction, complications, and middle-term mortality.
Results: The average follow-up duration was 48 months. There were 61, 47, and 33 patients in groups I, II, and III, respectively. Patients in group III exhibited an increased risk of prolonged total hospital LOS (P = .00). An increase in MV time (P = .03) and ICU LOS (P = .02) was also observed in this group, and these patients experienced greater mortality in 24 months following the surgery (P = .03). There was no association between the NLR and ventricular dysfunction (P = .26) and complications (P = .46).
Conclusion: A high preoperative NLR was associated with worse outcomes in patients with SV physiology undergoing the bidirectional Glenn procedure.
(© 2019 Wiley Periodicals, Inc.)
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فهرسة مساهمة: Keywords: bidirectional Glenn procedure; congenital heart disease; neutrophil-lymphocyte ratio; single-ventricle physiology
تواريخ الأحداث: Date Created: 20191130 Date Completed: 20200831 Latest Revision: 20200831
رمز التحديث: 20231215
DOI: 10.1111/jocs.14381
PMID: 31782834
قاعدة البيانات: MEDLINE
الوصف
تدمد:1540-8191
DOI:10.1111/jocs.14381