دورية أكاديمية
Influence of Obesity on Serum Concentrations of Acute-Phase Proteins in Horses.
العنوان: | Influence of Obesity on Serum Concentrations of Acute-Phase Proteins in Horses. |
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المؤلفون: | Girardi FM; Veterinary Departament, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil., da Fonseca LA; Veterinary Departament, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil. Electronic address: leandroabreu@ufv.br., Ribeiro Filho JD; Veterinary Departament, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil., Souto PC; Veterinary Departament, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil., Ferreira DAC; Veterinary Departament, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil., Dornelas LRSM; Veterinary Departament, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil., Bento LD; Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., de Carvalho Filho WP; Veterinary Departament, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil. |
المصدر: | Journal of equine veterinary science [J Equine Vet Sci] 2019 Dec; Vol. 83, pp. 102810. Date of Electronic Publication: 2019 Oct 18. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 8216840 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0737-0806 (Print) Linking ISSN: 07370806 NLM ISO Abbreviation: J Equine Vet Sci Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2003- : New York : Elsevier Original Publication: [Wildomar, CA : William E. Jones, c1981- |
مواضيع طبية MeSH: | Acute-Phase Proteins/*metabolism , Horse Diseases/*blood , Obesity/*veterinary, Animals ; Brazil ; Electrophoresis, Polyacrylamide Gel/veterinary ; Horses ; Obesity/blood |
مستخلص: | Obesity in human and veterinary medicine is one of the most complex challenges within emerging diseases in the context of health. The problem of obesity in horses results in severe comorbidities; therefore, acute-phase proteins should be investigated for fluctuations increasing or decreasing by at least 25% in response to inflammation; these are candidates for future biomarkers and might provide new perspectives on early diagnosis and prognosis. Serum samples were analyzed in nine healthy animals (C) and nine obese animals (O). The proteins were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and the concentrations determined by computerized densitometry; matrix assisted laser desorption ionization time of flight mass spectrometry/TOF mass spectrometry was performed to identify the proteins, and the results obtained were compared to the Equidae and Metazoa taxon protein database deposited in UNIPROT using the MASCOT application. Three proteins presented a difference between the groups; ceruloplasmin (Cp), α (Copyright © 2019 Elsevier Inc. All rights reserved.) |
فهرسة مساهمة: | Keywords: Acute-phase response; Biomarkers; Inflammation; obesity |
المشرفين على المادة: | 0 (Acute-Phase Proteins) |
تواريخ الأحداث: | Date Created: 20191204 Date Completed: 20200701 Latest Revision: 20220531 |
رمز التحديث: | 20240628 |
DOI: | 10.1016/j.jevs.2019.102810 |
PMID: | 31791530 |
قاعدة البيانات: | MEDLINE |
تدمد: | 0737-0806 |
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DOI: | 10.1016/j.jevs.2019.102810 |